Additional Contact Information
Martina Lahmann is working at the Organic Chemistry/Life Science interface (Chemical Biology). Her expertise is in organic synthesis, carbohydrate and glycoconjugate chemistry.
Martina received her diploma in Chemistry at the University of Hamburg, Germany, in 1994. She continued her work in the group of Prof. Joachim Thiem and obtained her Ph.D. in Organic Chemistry in 1997. Thereafter she moved to Stockholm University, Sweden, to work as a postdoc with Prof. Per J. Garegg and Prof. Stefan Oscarson. In 2002 she moved to Göteborg University, Sweden, to supervise the part of Stefan’s group which was relocated to Göteborg University, to lecture Organic Chemistry, and then to develop her independent research. In September 2005 she received the Docent degree in Organic Chemistry from Göteborg University. After a year in the Arrhenius Laboratory at Stockholm University, focussing on her research, Martina joined us at Bangor in September 2007.
The major focus on her current research comprises the development of new tools and structures for the identification and analysis of carbohydrate recognition domains, directing to a deeper understanding of carbohydrate-protein interactions on the molecular level, which eventually allows a more rational design and development of carbohydrate-based pharmaceuticals. Adhesion of bacteria to human glycoconjugate receptors is a crucial step in the development of many diseases and is often mediated by carbohydrate-protein interactions. As model system, she focuses on the binding of Helicobacter pylori (collaborators S. Oscarson, University College Dublin, and T. Borén, University of Umeå) which induces chronic inflammation by attaching itself to carbohydrate structures in the stomach lining. Another bacterial target is the uropathogenic Escherichia coli (UPEC), accounting for more than 80 % of urinary tract infections. To inhibit the adhesion of bacteria to the bladder is proposed to be an alternative approach to challenge antibiotic resistance. Transferred to the lab-bench this spans from “plain” oligosaccharide synthesis (e.g. Lewis-blood group structures), variously tagged carbohydrate structures (e.g. photolabeling, selenoglycosides) to designed conjugates (e.g. glycocluster, dendrimers).
The exploration of glycosylation reactions, e.g. solvent dependency, and the development of protecting group- and conjugation techniques represents another research-area.
Research Interests
Research
Welcome to the Carbohydrate Lab!
In our laboratory almost everything orbits carbohydrates. Carbohydrates represent - also outside the lab - the most abundant family of nature products.
Everybody has probably heard about
- their role as energy storage, e.g. as sucrose A - in everyday language just called ‘sugar’,
- their capability supporting tissue in plants, e.g., cellulose B helps building up even the largest trees,
- their ability in keeping many arthropods (as insects, spiders and crustaceans) protected in their sometimes pretty hard ‘skin’, e.g., the lobster’s shell consist mainly of a polysaccharide called chitin C.
However, complex oligosaccharide structures are essential to get biological systems working and carbohydrate structures placed e.g. on the outside of a cell-wall can behave both as flypaper and as signpost for other bio molecules. Two examples:
- the “ABO-blood-groups” are assigned by carbohydrate structures present on the surface of (red blood) cells
- too old red blood cells are sorted out by the liver if they present too little sialic acids (certain carbohydrates) on their surface (because the red blood cells loose them when getting older)
As more as we understand the relevance of carbohydrates and their conjugates, the interest in possible pharmaceutical applications is growing (e.g. development of vaccines). However, compared to peptides the construction of oligosaccharides is not as automated and still often governed by ‘trial and error’.
At this point our research begins:
Our general aim is it to understand the chemistry of carbohydrates as much as possible by studying glycosylation reactions and the development of protecting group-techniques. By doing this, we produce many biologically interesting compounds which are further examined by biochemists and biologists. Since ‘naked’ oligosaccharides are usually too small to produce a response in a biological system, we have to ‘inflate’ them by connecting them to carrier, e.g. proteins. In other cases it is useful to bunch several copies of the carbohydrate structures together by preparing glycoclusters or glycodendrimers. Thus, conjugation of carbohydrate structures via various spacer molecules to a carrier is another area of our research.
Some introductionary reading:
Architectures of Multivalent Glycomimetics for Probing Carbohydrate-Lectin Interactions.
Martina Lahmann
Top. Curr. Chem. 288 (2009), 17-65.
In: "Glycoscience and Microbial Adhesion", Th. K. Lindhorst, St. Oscarson (Eds.), Springer, Berlin/Heidelberg 2009.
Postgraduate Project Opportunities
Publications
2021
- PublishedSakurai Anomeric Allylation of Methyl α-Pyranosides
Bouillon, M., Williams, R. M., Lahmann, M. & McCabe, O., Jan 2021, Carbohydrate chemistry: Proven synthetic methods. Kosma, P., Wrodnigg, T. M. & Stutz, A. (eds.). Boca Raton: CRC Press, Vol. 5. p. 55-63
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review - PublishedSynthesis of Allyl and Dec-9-Enyl α-d-Mannopyranosides from d-Mannose
Vacchini, M., Cipolla, L., Guizzardi, R., La Ferla, B. & Lahmann, M., Jan 2021, Carbohydrate Chemistry: Proven synthetic methods. Kosma, P., Wrodnigg, T. M. & Stutz, A. (eds.). Boca Raton: CRC Press, Vol. 5. p. 189-197
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
2020
- PublishedAn investigation of the antileishmanial properties of semi-synthetic saponins
Anderson, O., Beckett, J., Briggs, C. C., Natrass, L. A., Cranston, C. F., Wilkinson, E. J., Owen, J., Williams, R. M., Loukaidis, A., Bouillon, M., Pritchard, D., Lahmann, M., Baird, M. & Denny, P. W., 1 Jul 2020, In: Medicinal Chemistry. 11, 7, p. 833-842
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of Anemoclemosides A and B, two Saponins Isolated from Anemoclema glaucifolium
Bouillon, M., Bertocco, K., Bischoff, L., Buri, M., Davies, L. R., Wilkinson, E. J. & Lahmann, M., 31 Dec 2020, In: European Journal of Organic Chemistry. 2020, 48, p. 7470-7473
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of Type 1 Lewis b hexasaccharide antigen structures featuring flexible incorporation of L-[U-13C6]-fucose for NMR binding studies
Long, M., Ni Cheallaigh, A., Reihill, M., Oscarson, S. & Lahmann, M., 21 Jun 2020, In: Organic and Biomolecular Chemistry. 18, 23, p. 4452-4458
Research output: Contribution to journal › Article › peer-review
2019
- PublishedArchitecture and Evolution of Blade Assembly in β-propeller Lectins
Bonnardel, F., Kumar, A., Wimmerova, M., Lahmann, M., Perez, S., Varrot, A., Lisacek, F. & Imberty, A., 7 May 2019, In: Structure. 27, 5, p. 764-775
Research output: Contribution to journal › Article › peer-review
2018
- PublishedNEW BIS ESTERS OF IVY SAPOGENINS FOR RUMINANTS
Al-Dulayymi, J., Bouillon, M., Braganca, R., Preskett, D. & Lahmann, M., 10 Oct 2018, Patent No. WO/2016/193309
Research output: Patent
2017
- PublishedAntiprotozoal effect of saponins in the rumen can be enhanced by chemical modifications in their structure
Ramos-Morales, E., De La Fuente, G., Duval, S., Wehrli, C., Bouillon, M., Lahmann, M., Preskett, D., Braganca, R. & Newbold, J., 16 Mar 2017, In: Frontiers in Microbiology. 8, 399.
Research output: Contribution to journal › Article › peer-review - PublishedImproving the antiprotozoal effect of saponins in the rumen by combination with glycosidase inhibiting iminosugars or by modification of their chemical structure
Ramos-Morales, E., de la Fuente, G., Nash, R. J., Braganca, R., Duval, S., Bouillon, M., Lahmann, M. & Newbold, J., 8 Sep 2017, In: PLoS ONE. 12, 9, e0184517.
Research output: Contribution to journal › Article › peer-review - PublishedPreparation and immunogenicity of gold glyco-nanoparticles as antipneumococcal vaccine model
Vetro, M., Safari, D., Fallarini, S., Salsabila, K., Lahmann, M., Penades, S., Lay, L., Marradi, M. & Compostella, F., Jan 2017, In: Nanomedicine. 12, 1
Research output: Contribution to journal › Article › peer-review
2016
- PublishedIsolation and characterisation of 13 pterosins and pterosides from bracken (Pteridium aquilinum (L.) Kuhn) rhizome
Mohammad, R., Nur-e-Alam, M., Lahmann, M., Parveen, I., Tizzard, G. J., Coles, S. J., Fowler, M., Drake, A. F., Heyes, D. & Thoss, V., Aug 2016, In: Phytochemistry. 128, p. 82-94
Research output: Contribution to journal › Article › peer-review - PublishedStructural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori
Moonens, K., Gideonsson, P., Subedi, S., Bugaytsova, J., Romaõ, E., Mendez, M., Nordén, J., Fallah, M., Rakhimova, L., Shevtsova, A., Lahmann, M., Castaldo, G., Brännström, K., Coppens, F., Lo, A. W., Ny, T., Solnick, J. V., Vandenbussche, G., Oscarson, S., Hammarström, L., Arnqvist, A., Berg, D. E., Muyldermans, S., Borén, T. & Remaut, H., 13 Jan 2016, In: Cell Host and Microbe. 19, 1, p. 55-66
Research output: Contribution to journal › Article › peer-review
2015
- PublishedA roadmap for Glycoscience in Europe: White Paper
Lahmann, M., 2015, Manchester University Press. 16 p.
Research output: Book/Report › Commissioned report - PublishedStereoselective Reduction Using Sodium Triacetoxyborodeuteride: Synthesis of Methyl 2,3-Di-O-benzyl-α-d-(4-2H)-glucopyranoside
Mobarak, H., Engstrom, O., Lahmann, M., Widmalm, G., Roy, R. (ed.) & Vidal, S. (ed.), 27 May 2015, Carbohydrate Chemistry: Proven Synthetic Methods: Volume 3. 2015 ed. CRC Press, p. 81-88
Research output: Chapter in Book/Report/Conference proceeding › Chapter
2013
- PublishedA Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia - Structure, Specificity and Possible Role in Fungal Pathogenicity
Houser, J., Komarek, J., Kostlanova, N., Cioci, G., Varrot, A., Kerr, S. C., Lahmann, M., Balloy, V., Fahy, J. F., Chignard, M., Imberty, A. & Wimmerova, M., 10 Dec 2013, In: PLoS ONE.
Research output: Contribution to journal › Article › peer-review - PublishedLactosamine from lactulose via the Heyns rearrangement: a practical protocol
Shan, Y., Oulaidi Lamiable, F. & Lahmann, M., 24 Jul 2013, In: Tetrahedron Letters. 54, 30, p. 3960-3961
Research output: Contribution to journal › Article › peer-review - PublishedMultivalent glycoconjugates as anti-pathogenic agents
Bernardi, A., Jimenez-Barbero, J., Casnati, A., De Castro, C., Darbre, T., Fieschi, F., Finne, J., Funken, H., Jaeger, K-E., Lahmann, M., Lindhorst, T. K., Marradi, M., Messner, P., Molinaro, A., Murphy, P. V., Nativi, C., Oscarson, S., Penades, S., Peri, F., Pieters, R. J., Renaudet, O., Reymond, J-L., Richichi, B., Rojo, J., Sansone, F., Schaeffer, C., Turnbull, W. B., Velasco-Torrijos, T., Vidal, S., Vincent, S., Wennekes, T., Zuilhof, H. & Imberty, A., 2013, In: Chemical Society Reviews. 42, 11, p. 4709-4727
Research output: Contribution to journal › Article › peer-review
2012
- PublishedGold nanoparticles as carriers for a synthetic Streptococcus pneumoniae type 14 conjugate vaccine
Safari, D., Marradi, M., Chiodo, F., Dekker, H. A., Shan, Y., Adamo, R., Oscarson, S., Rijkers, G. T., Lahmann, M., Kamerling, J. P., Penadés, S. & Snippe, H., 1 May 2012, In: Nanomedicine. 7, 5, p. 651-662
Research output: Contribution to journal › Article › peer-review - PublishedThe Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin FimH
Wellens, A., Lahmann, M., Touaibiall, M., Vaucher, J., Oscarson, S., Roy, R., Ramaut, H. & Bouckaert, J., 2012, In: Biochemistry. 51, 24, p. 4790-4799
Research output: Contribution to journal › Article › peer-review
2011
- PublishedTransformations of chromanol and tocopherol and synthesis of ascorbate conjugates
Lahmann, M. & Thiem, J., 4 Mar 2011, In: Tetrahedron. 67, 9, p. 1654-1664
Research output: Contribution to journal › Article › peer-review
2010
- PublishedA TNF-like trimeric lectin domain from Burkholdeda cenocepacia with specificity for fucosylated human histo-blood group antigens.
Šulák, O., Delia, M., Lahmann, M., Varrot, A., Imberty, A. & Wimmerová, M., 13 Jan 2010, In: Structure. 18, 1, p. 59-72
Research output: Contribution to journal › Article › peer-review - PublishedGlycocluster design for improved avidity and selectivity in blocking human lectin/plant toxin binding to glycoproteins and cells.
Andre, S., Lahmann, M., Gabius, H. J. & Oscarson, S., 6 Dec 2010, In: Molecular Pharmaceutics. 7, 6, p. 2270-2279
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of 6-PEtN-α-D-GalpNAc-(1–>6)-β-D-Galp-(1–>4)-β-D-GlcpNAc-(1–>3)-β-D-Galp-(1–>4)-β-D-Glcp, a Haemophilus influenzae lipopolysacharide structure, and biotin and protein conjugates thereof.
Sundgren, A., Lahmann, M. & Oscarson, S., 26 Jul 2010, In: Beilstein Journal of Organic Chemistry. 6, p. 704-708
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of the Lewis b pentasaccharide and a HAS-conjugate thereof.
Fourniere, V., Skantz, L., Sajtos, F., Oscarson, S. & Lahmann, M., 22 Jul 2010, In: Tetrahedron.
Research output: Contribution to journal › Article › peer-review
2009
- PublishedArchitectures of Multivalent Glycomimetics for Probing Carbohydrate–Lectin Interactions.
Lahmann, M., 1 Jan 2009, In: Topics in Current Chemistry. 288, p. 17-65
Research output: Contribution to journal › Article › peer-review - PublishedReversible non-covalent derivatisation of carbon nanotubes with glycosides.
Andersson, C. H., Lahmann, M., Oscarson, S. & Grennberg, H., 1 Jan 2009, In: Soft Matter. 5, 14, p. 2713-2716
Research output: Contribution to journal › Article › peer-review
2008
- PublishedAtomic mapping of the sugar interactions in one-site and two-site mutants of Cyanovirin-N by NMR spectroscopy
Sandstrom, C., Hakkarainen, B., Matei, E., Glinchert, A., Lahmann, M., Oscarson, S., Kenne, L. & Gronenborn, A. M., 25 Mar 2008, In: Biochemistry. 47, 12, p. 3625-3635
Research output: Contribution to journal › Article › peer-review - PublishedIdentification of the smallest structure capable of evoking opsonophagocytic antibodies against Streptococcus pneumoniae type 14
Safari, D., Dekker, H. A. T., Joosten, J. A. F., Michalik, D., de Souza, A. C., Adamo, R., Lahmann, M., Sundgren, A., Oscarson, S., Kamerling, J. P. & Snippe, H., Oct 2008, In: Infection and Immunity. 76, 10, p. 4615-4623
Research output: Contribution to journal › Article › peer-review - PublishedInvestigations of glycosylation reactions with 2-N-acetyl-2N,3O-oxazolidinone-protected glucosamine donors.
Olsson, J. D., Eriksson, L., Lahmann, M. & Oscarson, S., 19 Sep 2008, In: Journal of Organic Chemistry. 73, 18, p. 7181-7188
Research output: Contribution to journal › Article › peer-review
2007
- PublishedNMR study of hydroxy protons of di- and trimannosides, substructures of Man-9
Hakkarainen, B., Kenne, L., Lahmann, M., Oscarson, S. & Sandstrom, C., 1 Dec 2007, In: Magnetic Resonance in Chemistry. 45, 12, p. 1076-1080
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of urine drug metabolites: glucuronic acid glycosides of phenol intermediates
Arewang, C. J., Lahmann, M., Oscarson, S. & Tiden, A. K., 21 May 2007, In: Carbohydrate Research. 342, 7, p. 970-974
Research output: Contribution to journal › Article › peer-review
2006
- PublishedSynthesis of monodeoxy analogues of the trisaccharide alpha-D-Glcp-(1 -> 3)-alpha-D-Manp-(1 -> 2)-alpha-D-ManpOMe recognised by calreticulin/calnexin
Gemma, E., Lahmann, M. & Oscarson, S., 24 Jul 2006, In: Carbohydrate Research. 341, 10, p. 1533-1542
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of oligosaccharides corresponding to Vibrio cholerae O139 polysaccharide structures containing dideoxy sugars and a cyclic phosphate
Turek, D., Sundgren, A., Lahmann, M. & Oscarson, S., 1 Jan 2006, In: Organic and Biomolecular Chemistry. 4, 7, p. 1236-1241
Research output: Contribution to journal › Article › peer-review - Publishedbeta-propeller crystal structure of Psathyrella velutina lectin: An integrin-like fungal protein interacting
Cioci, G., Mitchell, E. P., Chazalet, V., Debray, H., Oscarson, S., Lahmann, M., Gautier, C., Breton, C., Perez, S. & Imberty, A., 14 Apr 2006, In: Journal of Molecular Biology. 357, 5, p. 1575-1591
Research output: Contribution to journal › Article › peer-review
2005
- PublishedBlock synthesis of Streptococcus pneumoniae type 14 capsular polysaccharide structures
Sundgren, A., Lahmann, M. & Oscarson, S., 1 May 2005, In: Journal of Carbohydrate Chemistry. 24, 4-6, p. 379-391
Research output: Contribution to journal › Article › peer-review - PublishedEthyl 2-acetamido-4,6-di-O-benzyl-2,3-N,O-carbonyl-2-deoxy-1-thio-beta-glycopyranoside as a versatile GlcNAc donor
Boysen, M., Gemma, E., Lahmann, M. & Oscarson, S., 1 Jan 2005, In: Chemical Communications. 24, p. 3044-3046
Research output: Contribution to journal › Article › peer-review - PublishedImpact of natural variation in bacterial F17G adhesins on crystallization behaviour
Buts, L., Wellens, A., Van Molle, I., Wyns, L., Loris, R., Lahmann, M., Oscarson, S., de Greve, H. & Bouckaert, J., 1 Aug 2005, In: Acta Crystallographica Section D: Biological Crystallography. 61, 8, p. 1149-1159
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of the tetrasaccharide alpha-D-Glcp(1 -> 3)-alpha-D-Manp-(1 -> 2)-alpha-D-Manp-(1 -> 2)-alpha-D-Manp recognized by calreticulin/calnexin
Gemma, E., Lahmann, M. & Oscarson, S., 21 Nov 2005, In: Carbohydrate Research. 340, 16, p. 2558-2562
Research output: Contribution to journal › Article › peer-review - PublishedThe fucose-binding lectin from Ralstonia solanacearum - A new type of beta-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan
Kostlanova, N., Mitchell, E. P., Lortat-Jacob, H., Oscarson, S., Lahmann, M., Gilboa-Garber, N., Chambat, G., Wimmerova, M. & Imberty, A., 29 Jul 2005, In: Journal of Biological Chemistry. 280, 30, p. 27839-27849
Research output: Contribution to journal › Article › peer-review
2004
- PublishedFunctional adaptation of BabA, the H-pylori ABO blood group antigen binding adhesion
Aspholm-Hurtig, M., Dailide, G., Lahmann, M., Kalia, A., Ilver, D., Roche, N., Vikstrom, S., Sjostrom, R., Linden, S., Backstrom, A., Lundberg, C., Arnqvist, A., Mahdavi, J., Nilsson, U. J., Velapatino, B., Gilman, R. H., Gerhard, M., Alarcon, T., Lopez-Brea, M., Nakazawa, T., Fox, J. G., Correa, P., Dominguez-Bello, M. G., Perez-Perez, G. I., Blaser, M. J., Normark, S., Carlstedt, I., Oscarson, S., Teneberg, S., Berg, D. E. & Boren, T., 1 Jul 2004, In: Science. 305, 5683, p. 519-522
Research output: Contribution to journal › Article › peer-review - PublishedLigands of the asialoglycoprotein receptor for targeted gene delivery, part 1: Synthesis of and binding studies with biotinylated cluster glycosides containing N-acetylgalactosamine
Westerlind, U., Westman, J., Tornquist, E., Smith, C. I., Oscarson, S., Lahmann, M. & Norberg, T., 1 Jan 2004, In: Glycoconjugate Journal. 21, 5, p. 227-241
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of the Lewis b hexasaccharide and HSA-conjugates thereof.
Lahmann, M., Bulow, L., Teodorovic, P., Gyback, H. & Oscarson, S., 1 Sep 2004, In: Glycoconjugate Journal. 21, 5, p. 251-256
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of urine drug metabolites: glucuranosyl esters of carboxymefloquine, indoprofen, (S)-naproxen and desmethyl (S)-naproxen
Lahmann, M., Bergstrom, M. A., Turek, D. & Oscarson, S., 1 Dec 2004, In: Journal of Carbohydrate Chemistry. 23, 2, p. 123-132
Research output: Contribution to journal › Article › peer-review
2003
- PublishedDesign and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2 '-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex
Oscarsson, K., Lahmann, M., Lindberg, J., Kangasmetsa, J., Unge, T., Oscarson, S., Hallberg, A. & Samuelsson, B., 20 Mar 2003, In: Bioorganic and Medicinal Chemistry. 11, 6, p. 1107-1115
Research output: Contribution to journal › Article › peer-review - PublishedSmI2/water/amine mediates cleavage of allyl ether protected alcohols: Application in carbohydrate synthesis and mechanistic considerations
Dahlen, A., Sundgren, A., Lahmann, M., Oscarson, S. & Hilmersson, G., 30 Oct 2003, In: Organic Letters. 5, 22, p. 4085-4088
Research output: Contribution to journal › Article › peer-review - PublishedSolving the phase problem for carbohydrate-binding proteins using selenium derivatives of their ligands: a case study involving the bacterial F17-G adhesin
Buts, L., Loris, R., De Genst, E., Oscarson, S., Lahmann, M., Messens, J., Brosens, E., Wyns, L., De Greve, H. & Bouckaert, J., 1 Jun 2003, In: Acta Crystallographica Section D: Biological Crystallography. 59, 6, p. 1012-1015
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of dihydrodiosgenin glycosides as mimetics of bidesmosidic steroidal saponins
Suhr, R., Lahmann, M., Oscarson, S. & Thiem, J., 17 Oct 2003, In: European Journal of Organic Chemistry. 20, p. 4003-4011
Research output: Contribution to journal › Article › peer-review - PublishedThe fimbrial adhesin F17-G of enterotoxigenic Escherichia coli has an immunoglobulin-like lectin domain that binds N-acetylglucosamine
Buts, L., Bouckaert, J., De Genst, E., Loris, R., Oscarson, S., Lahmann, M., Messens, J., Brosens, E., Wyns, L. & De Greve, H., 1 Aug 2003, In: Molecular Microbiology. 49, 3, p. 705-715
Research output: Contribution to journal › Article › peer-review
2002
- PublishedA facile approach to diosgenin and furostan type saponins bearing a 3 beta-chacotriose moiety
Lahmann, M., Gyback, H., Garegg, P. J., Oscarson, S., Suhr, R. & Thiem, J., 19 Nov 2002, In: Carbohydrate Research. 337, 21-23, p. 2153-2159
Research output: Contribution to journal › Article › peer-review - PublishedInvestigation of the reactivity difference between thioglycoside donors with variant aglycon parts
Lahmann, M. & Oscarson, S., 1 Aug 2002, In: Canadian Journal of Chemistry. 80, 8, p. 889-893
Research output: Contribution to journal › Article › peer-review - PublishedSynthesis of a polyphosphorylated GPI-anchor core structure.
Lahmann, M., Garegg, P. J., Konradsson, P. & Oscarson, S., 1 Aug 2002, In: Canadian Journal of Chemistry. 80, 8, p. 1105-1111
Research output: Contribution to journal › Article › peer-review
2000
- PublishedOne-pot oligosaccharide synthesis exploiting solvent reactivity effects
Lahmann, M. & Oscarson, S., 30 Nov 2000, In: Organic Letters. 2, 24, p. 3881-3882
Research output: Contribution to journal › Article › peer-review
1997
- PublishedSynthesis of alpha-tocopheryl oligosaccharides
Lahmann, M. & Thiem, J., 26 Mar 1997, In: Carbohydrate Research. 299, 1-2, p. 23-31
Research output: Contribution to journal › Article › peer-review
Activities
2015
- Member of COST Management Committee, European Cooperation in Science and Technology (COST Network)
2015 →
Activity: Types of External academic engagement - Contribution to the work of national or international committees and working groups (Member)
Projects
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Towards the Synthesis of a Fucosylated Chondroitin Sulfate Library, part 2
01/06/2016 – 23/02/2017 (Finished)
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Towards the Synthesis of a Fucosylated Chondroitin Sulfate Library
01/06/2015 – 24/02/2017 (Finished)
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Saponins evaluation for efficacy against liver fluke
01/04/2015 – 01/08/2019 (Finished)
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Highly bioactive saponins from a cell culture approach
03/02/2014 – 08/09/2016 (Finished)
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01/10/2012 – 31/08/2016 (Finished)
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01/01/2001 – 14/12/2009 (Finished)