Nafees Din

Research Associate

Research Overview

After my graduation in dentistry in 1996, I practiced general dentistry for about 10 years including three years specialist training in Orthodontics. In 2006, I developed interest in public health research and started my first job as a research assistant in public health in this department in 2008 after my master in dental public health. Since then, I have gained knowledge of and experience in systematic reviews, mixed treatment comparisons, randomised controlled trials of complex social interventions, mixed method process evaluation, large routinely collected database analyses and realist review methods.


Educational Background:

2006-2007-MSc: Dental Public Health, Queen Mary University of London

2005-2007-MFDS RCS: Royal College of Surgeons, England

1992-1996-B.D.S. (Dentistry): Nishtre Medical College/Baha Uddin Zakariya University, Multan Pakistan


Research grants:

Neal RD, Din NU. Root causes of diagnosis and treatment delay: International Cancer Benchmarking Partnership (ICBP) Module 4 for Wales. Cancer Research Wales £114K 2013-14.

2011: Welsh School of Primary Care. Din NU, Williams N. Activity Increase Despite Arthritis (AÏDA). Development of research proposal for a definitive phase III RCT. (£10K).


Key publications

Roberts, J. L., Pritchard, A., Williams, M., Totton, N., Morrison, V., Din, N., & Williams, N. (2018). Mixed methods process evaluation of an enhanced community-based rehabilitation intervention for elderly hip fracture patients. BMJ Open. 8, 8, p. e021486

Charles, J., Roberts, L., Din, N., Williams, N., Yeo, T., Edwards, T. (2018). Preferences of older patient regarding hip fracture rehabilitation service configuration: A feasibility discrete choice experiment. Journal of Rehabilitation Medicine. 2018 May 14. doi: 10.2340/16501977-2350. [Epub ahead of print]

Williams, N., Mawdesley, K., Roberts, J., Din, N., Totton, N., Charles, J., Hoare, Z., Edwards, R. (2017). Hip fracture in the elderly multidisciplinary rehabilitation (FEMuR) feasibility study: testing the use of routinely collected data for future health economic evaluations. Pilot and Feasibility Studies (2018) 4:76

Lewis R, Hendry M, Din N, Nafees S, Stanciu A, Hendry A, Teoh H, Lloyd T, Parsonage R, Neal R, Collier G, Huws DW (2017).  Factors associated with lung cancer survival – systematic mapping review and overview of systematic reviews. Report submitted to Public Health Wales (Paper submitted to journal)

Williams, N., Roberts, J., Din, N., Charles, J., Totton, N., Williams, M., Mawdesley, K., Hawkes, C., Morrison, V., Lemmey, A., Edwards, R., Hoare, Z., Pritchard, A., Woods, R., Alexander, S., Sackley, C., Logan, P., Wilkinson, C. & Rycroft-Malone, J. (2017).

Developing a multidisciplinary rehabilitation package following hip fracture and testing in a randomised feasibility study: Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR). Health Technology Assessment 21 44 DOI: 10.3310/hta21440

Roberts, J. L., Din, N., Williams, M., Hawkes, C., Charles, J., Hoare, Z., Morrison, V., Alexander, S., Lemmey, A., Sackley, C., Logan, P., Wilkinson, C., Rycroft-Malone, J. & Williams. (2017). Development of an evidence-based complex intervention for community rehabilitation of patients with hip fracture using realist review, survey and focus groups. BMJ Open, 7(10), [e014362]. DOI: 10.1136/bmjopen-2016-014362

Charles, J., Roberts, J., Din, N., Williams, N., Yeo, S. T., & Edwards, R. (2016). Use of a discrete choice experiment approach to elicit patients’ preferences for hip fracture rehabilitation services as part of a feasibility study. The Lancet, 388(Supplement 2), S35. DOI: 10.1016/S0140-6736(16)32271-1

Williams NH, Roberts JL, Din NU, Totton N, Charles JM, Hawkes CA, Morrison V, Hoare Z, Williams M, Pritchard AW, Alexander S, Lemmey A, Woods RT, Sackley C, Logan P, Edwards RT, and Wilkinson C. Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR): a phase II randomised feasibility study of a multidisciplinary rehabilitation package following hip fracture. BMJ Open 2016;6: e012422. doi:10.1136/ bmjopen-2016-012422

Din NU, Ukoumunne OC, Rubin G, Hamilton W, Carter B, Stapley S, et al. (2015) Age and Gender Variations in Cancer Diagnostic Intervals in 15 Cancers: Analysis of Data from the UK Clinical Practice Research Datalink. PLoS ONE 10(5): e0127717. doi:10.1371/journal.pone.0127717

Nefyn H Williams, Claire Hawkes, Nafees Ud Din, Jessica Roberts, Joanna M Charles, Val Morrison, Zoe Hoare, Rhiannon T Edwards, Glynne Andrew, Swapna Alexander, Andrew Lemmey, Bob Woods, Catherine Sackley, Pip Logan, David Hunnisett, Kevin Mawdesley, Clare Wilkinson. Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR): design of a Phase II randomised feasibility study of a multidisciplinary rehabilitation package following hip fracture [ISRCTN22464643]. BMC Pilot and Feasibility Studies 2015, 1:13 doi:10.1186/s40814-015-0008-0

Neal RD, Tharmanathan P, France B, Din NU, Cotton S, Fallon-Ferguson J, Hamilton W, Hendry A, Hendry M, Lewis R, Macleod U, Mitchell ED, Pickett M, Rai T, Shaw K, Stuart N, Tørring ML, Wilkinson C, Williams B, Williams N, Emery J. Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review. British Journal of Cancer (2015); 1-16; doi: 10.1038/bjc.2015.48

Din UD, Moore GF, Murphy S, Wilkinson C, Williams NH. Health professionals' perspectives on excercise referral and physical activity promotion in primary care: Findings from a process evaluation of the National Excercise Referral Schem in Wales. DOI: 10.1177/0017896914559785

Fitzsimmons D, Phillips C, Bennett H, Jones M, Williams NH, Lewis R, Sutton A< Matar H, Din UD, Burton K, Nafees S, Hendry M, Rickard I, Wilkinson C. Cost-effectiveness of different strategies to manage patients with Sciatica. Science Direct. May 2014. DOI: 10.1016/j.pain.2014.04.008

R D Neal, N U Din, W Hamilton, O C Ukoumunne, B Carter, S Stapley and G Rubin. Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database. Br J Cancer. 2014 Feb 4;110(3):584-92.

Joanna M Charles, Rhiannon Tudor-Edwards, Nefyn Williams, Nafees Din. The application of realist synthesis review methods in public health economics. The Lancet - 29 November 2013 (Vol. 382, Page S28 ) DOI: 10.1016/S0140-6736(13)62453-8

Lewis R, Williams NH, Sutton AJ, Burton K, Din N, Matar HE, Hendry M, Phillips CJ, Nafees S, Fitzsimmons D, Rickard I, Wilkinson C, Comparative Clinical Effectiveness of Management Strategies for Sciatica: Systematic Review and Network Meta-Analyses, The Spine Journal (2013), doi: 10.1016/j.spinee.2013.08.049.

Graham F Moore, Lawrence Raisanen, Laurence Moore, Nafees Ud Din, Simon Murphy, (2013) "Mixed-method process evaluation of the Welsh National Exercise Referral Scheme", Health Education, Vol. 113 Issue: 6

Williams NH, Lewis R, Din NU, Matar HE, Fitzsimmons D, Phillips CJ, Sutton A, Burton K, Hendry M, Nafees S, Wilkinson C. A systematic review and meta-analysis of biological treatments targeting tumour necrosis factor α for sciatica. Eur Spine J. 2013.; Volume 22, Issue 9, pp 1921-1935

Nefyn Williams, Nafees Din, Jo Rycroft-Malone, Clare Wilkinson, Rhiannon Edwards, Jo Charles. Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR): developing a multidisciplinary rehabilitation package following hip fracture. PROSPERO 2012:CRD42012003208 Available from

Murphy S, Tudor Edwards R, Williams N, Raisanen L, Moore G, Linck P, Hounsome N, Ud Din N and Moore L. An evaluation of the effectiveness and cost effectiveness of the National Exercise Referral Scheme in Wales UK: a randomised controlled trial of a public health policy initiative. Journal of Epidemiology and Community Health (2012) doi:10.1136/jech-2011-200689

Lewis R, Williams N, Matar H, Din N, Fitzsimmons D, et al. The clinical effectiveness and cost-effectiveness of management strategies for sciatica: systematic review and economic model. Health Technol Assess 2011;15(39).

Simon Murphy, Larry Raisanen, Graham Moore, Rhiannon Tudor Edwards, Pat Linck , Natalia Hounsome, Nefyn Williams, Nafees Ud Din and Laurence Moore (2010) - The evaluation of the National Exercise Referral Scheme in Wales, Social Research, Number: 07/2010 Welsh Assembly Government, Cardiff.

Murphy S, Raisanen L, Moore G, Tudor Edwards R, Linck P, Williams N, Ud Din N,  Hale J  and Moore L (2010) A pragmatic randomised controlled trial of the Welsh National Exercise Referral Scheme: protocol for trial and integrated economic and process evaluation BMC Public Health, 2010, 10:352