Skip to main content
Home

Information for:

  • Alumni
  • Applicants
  • Current Students
  • Staff
  • Parents
  • Job Vacancies
  • Covid-19
  • Cymraeg
My country:

Main Menu

    • Study Options
      • Study Home
      • Why Study at Bangor?
      • Undergraduate Study
      • Postgraduate Taught Study
      • Postgraduate Research
      • Executive Education
      • Part-time Courses
      • January Start Courses
      • Degree Apprenticeships
      • Study Abroad
      • Work Experience
    • Study Advice
      • Apply
      • Already Applied?
      • Fees and Finances
      • Scholarships and Bursaries
      • Get Ready for University
      • Widening Access
    • Explore Bangor
      • Open Days and Visits
      • Virtual Student Experience
      • Magical Bangor

    Find a Course

    Order a Course Guide

    Open Days

    Clearing

    • Student Life
      • Student Life Home
      • Bangor and the Area
      • Social Life and Entertainment
      • Student Accommodation
      • Clubs and Societies
      • Sport
      • Virtual Student Experience
      • Videos and Vlogs
    • Your Experience at Bangor
      • Student Support
      • Skills and Employability
      • Study or Work Abroad
      • Fees and Finances

    Student Profiles

    Student Videos and Vlogs

    Welcome 2022

    • Choose Bangor
      • International Home
      • Why Bangor?
      • Location
      • Accommodation
      • Student Support
      • Contact Us
      • Bangor University's China website
    • Apply
      • Entry Requirements
      • Tuition Fees and Scholarships
      • How to Apply
      • Already Applied
      • Study Abroad
      • Exchanges
      • Worldwide Partners

    Country Specific Information

    Bangor University International College

    Find a Course

    Clearing 2023

    • Research
      • Research Home
      • About Our Research
      • Research in our Academic Schools
      • Research Institutes and Centres
      • Research Portal
      • Integrated Research and Impact Support (IRIS) Service
      • Energy
      • REF 2021
      • Research News
    • Postgraduate Research Opportunities
      • Postgraduate Research
      • Doctoral School
    • Events and Training Opportunities
      • Researcher Development
    • The University
      • About Us
      • Our Mission
      • Strategy 2030
      • Annual Report & Financial Statements
      • Our Location
      • Academic Schools and Colleges
      • Services and Facilities
      • Vice-Chancellor's Office
      • Working with Business
      • Working with the Community
      • Sustainability
      • Health and Wellbeing
      • Contact Us
    • Working for Us
      • Job Vacancies
    • University Management and Governance
      • Policies and Procedures
      • Slavery and Human Trafficking Statement
      • Management and Governance
    • University and the Community
      • Pontio
      • Sports Facilities
      • Conference Facilities
      • Places to Eat and Drink
      • Public Events
      • Widening Access
      • Services to Schools
    • Business Services
      • Business Services Home
    • Collaboration Hub
      • Collaboration Hub
    • Conferencing and Business Dining
      • Conferencing Facilities
      • Business Dining
    • Intellectual Property (IP) and Commercialisation
      • Intellectual Property (IP) and Commercialisation
    • News
      • Current News
      • Research News
      • Student News
    • Events
      • Events
    • Announcements
      • Flag Announcements
  • Open Days

    • Study Options
      • Study Home
      • Why Study at Bangor?
      • Undergraduate Study
      • Postgraduate Taught Study
      • Postgraduate Research
      • Executive Education
      • Part-time Courses
      • January Start Courses
      • Degree Apprenticeships
      • Study Abroad
      • Work Experience
    • Study Advice
      • Apply
      • Already Applied?
      • Fees and Finances
      • Scholarships and Bursaries
      • Get Ready for University
      • Widening Access
    • Explore Bangor
      • Open Days and Visits
      • Virtual Student Experience
      • Magical Bangor

    Find a Course

    Order a Course Guide

    Open Days

    Clearing

    • Student Life
      • Student Life Home
      • Bangor and the Area
      • Social Life and Entertainment
      • Student Accommodation
      • Clubs and Societies
      • Sport
      • Virtual Student Experience
      • Videos and Vlogs
    • Your Experience at Bangor
      • Student Support
      • Skills and Employability
      • Study or Work Abroad
      • Fees and Finances

    Student Profiles

    Student Videos and Vlogs

    Welcome 2022

    • Choose Bangor
      • International Home
      • Why Bangor?
      • Location
      • Accommodation
      • Student Support
      • Contact Us
      • Bangor University's China website
    • Apply
      • Entry Requirements
      • Tuition Fees and Scholarships
      • How to Apply
      • Already Applied
      • Study Abroad
      • Exchanges
      • Worldwide Partners

    Country Specific Information

    Bangor University International College

    Find a Course

    Clearing 2023

    • Research
      • Research Home
      • About Our Research
      • Research in our Academic Schools
      • Research Institutes and Centres
      • Research Portal
      • Integrated Research and Impact Support (IRIS) Service
      • Energy
      • REF 2021
      • Research News
    • Postgraduate Research Opportunities
      • Postgraduate Research
      • Doctoral School
    • Events and Training Opportunities
      • Researcher Development
    • The University
      • About Us
      • Our Mission
      • Strategy 2030
      • Annual Report & Financial Statements
      • Our Location
      • Academic Schools and Colleges
      • Services and Facilities
      • Vice-Chancellor's Office
      • Working with Business
      • Working with the Community
      • Sustainability
      • Health and Wellbeing
      • Contact Us
    • Working for Us
      • Job Vacancies
    • University Management and Governance
      • Policies and Procedures
      • Slavery and Human Trafficking Statement
      • Management and Governance
    • University and the Community
      • Pontio
      • Sports Facilities
      • Conference Facilities
      • Places to Eat and Drink
      • Public Events
      • Widening Access
      • Services to Schools
    • Business Services
      • Business Services Home
    • Collaboration Hub
      • Collaboration Hub
    • Conferencing and Business Dining
      • Conferencing Facilities
      • Business Dining
    • Intellectual Property (IP) and Commercialisation
      • Intellectual Property (IP) and Commercialisation
    • News
      • Current News
      • Research News
      • Student News
    • Events
      • Events
    • Announcements
      • Flag Announcements
  • Open Days

Information for:

  • Alumni
  • Applicants
  • Current Students
  • Staff
  • Parents
  • Job Vacancies
  • Covid-19
My country:

Search

Close

Breadcrumb

  • Cymraeg

Share this page:
  • Twitter
  • Facebook
  • LinkedIn

Dr Lovesha Sivanantharajah

Research Fellow

l.sivanantharajah@bangor.ac.uk

0009-0009-5160-2697

Dr Lovesha Sivanantharajah

View Dr Lovesha Sivanantharajah’s profile on the Bangor Research Portal

Overview

I am a molecular neurobiologist interested in understanding ­the mechanisms that underlie aging and neurodegeneration. My work uses the power of Drosophila melanogaster genetics coupled with an array of molecular, cellular, behavioural, imaging and bioinformatics approaches to better understand the molecular processes that define normal aging and identify how these processes are altered in pathological aging and neurodegenerative diseases.

Research Interests

Molecular Biology | Animal models | Neurodegeneration |Aging | Alzheimer's Disease

We are interested in understanding selective vulnerability of neurons to pathogenic proteins such as the tangle-forming protein, tau, in Alzheimer's Disease.  This involves characterising neuronal vulnerability to tau variants and identifying genes that may mediate vulnerability or resistance to tau. 

Publications

2025

  • E-pub ahead of printExamining the vulnerability of adult neuron subtypes to tau-mediated toxicity in Drosophila
    Sivanantharajah, L., Mudher, A. & Shepherd, D., 5 Apr 2025, (E-pub ahead of print) In: Translational Psychiatry. 15, 127.
    Research output: Contribution to journal › Article › peer-review

2023

  • PublishedTau-mediated axonal degeneration is prevented by activation of the WldS pathway
    Stubbs, K., Batchelor, B., Sivanantharajah, L., Sealey, M., Ramirez-Moreno, M., Ruiz, E., Richardson, B., Perry, V. H., Newman, T. A. & Mudher, A., Apr 2023, In: Brain Communications. 5, 2, fcad052.
    Research output: Contribution to journal › Article › peer-review

2022

  • PublishedCurcumin as a Holistic Treatment for Tau Pathology
    Sivanantharajah, L. & Mudher, A., 19 May 2022, In: Frontiers in Pharmacology. 13, 903119.
    Research output: Contribution to journal › Article › peer-review

2019

  • PublishedAn evaluation of Drosophila as a model system for studying tauopathies such as Alzheimer's disease
    Sivanantharajah, L., Mudher, A. & Shepherd, D., 1 May 2019, In: Journal of Neuroscience Methods. 319, May, p. 77-88 12 p.
    Research output: Contribution to journal › Article › peer-review

2015

  • PublishedCurrent techniques for high-resolution mapping of behavioral circuits in Drosophila
    Sivanantharajah, L. & Zhang, B., Sept 2015, In: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology. 201, 9, p. 895-909 15 p.
    Research output: Contribution to journal › Review article › peer-review
  • PublishedDifferential pleiotropy and HOX functional organization
    Sivanantharajah, L. & Percival-Smith, A., 1 Feb 2015, In: Development Biology. 398, 1, p. 1-10 10 p.
    Research output: Contribution to journal › Review article › peer-review

2014

  • PublishedAcquisition of a Leucine Zipper Motif as a Mechanism of Antimorphy for an Allele of the Drosophila Hox Gene Sex Combs Reduced
    Sivanantharajah, L. & Percival-Smith, A., 1 May 2014, In: G3: Genes, Genomes, Genetics. 4, 5, p. 829-838
    Research output: Contribution to journal › Article › peer-review

2013

  • PublishedDevelopmental competence and the induction of ectopic proboscises in Drosophila melanogaster
    Percival-Smith, A., Sivanantharajah, L., Pelling, J. J. H. & Teft, W. A., Nov 2013, In: Development genes and evolution. 223, 6, p. 375-387 13 p.
    Research output: Contribution to journal › Article › peer-review

2009

  • PublishedAnalysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein
    Sivanantharajah, L. & Percival-Smith, A., 1 May 2009, In: Genetics. 182, 1, p. 191-203 13 p.
    Research output: Contribution to journal › Article › peer-review

Activities

2024

  • Using the fruit fly for research @ Darganfod Discover 2024 (Wrexham's Science Festival)

    Outreach event at which we will showcase the use of the fruit fly for research at the Association for the Study of Animal Behaviour (ASAB) booth at the Wrexam Science Festival.

    4 Aug 2024

    Activity: Types of Public engagement and outreach - Media article or participation (Contributor)
  • Southwest Fly Meeting at Bristol University

    Talk entitled "Understanding the nature of selective neuronal vulnerability to tau-mediated toxicity"

    26 Jun 2024

    Links:

    • https://www.bristol.ac.uk/phys-pharm-neuro/events/fly-meetings/
    Activity: Oral presentation (Speaker)
  • Alzheimer's Research UK Research Conference

    The UK’s largest dementia research conference taking place at the ACC in Liverpool Alzheimer’s Research UK Conference provides a fantastic chance to gain insights from colleagues working across basic, translational and clinical dementia research.

    20 Mar 2024 – 21 Mar 2024

    Links:

    • https://www.alzheimersresearchuk.org/research/for-researchers/research-conference/
    Activity: Participation in Academic conference (Speaker)

Projects

  • Identifying molecular mechanisms in differential vulnerability of neurons to tau-mediated toxicity

    01/06/2022 – 30/06/2026 (Active)

  • HEFCW HEIR COVID extension to Charities bid (R35C40, F006505)

    01/04/2021 – 31/10/2021 (Finished)

  • Understanding the basis for selective vulnerability of differentneuronal populations

    12/01/2017 – 31/07/2023 (Finished)

Home

About Us

Academic Schools and Colleges

School of Environmental and Natural Sciences

  • Staff
    • Dr Lovesha Sivanantharajah
Home

Follow Us

  • Twitter
  • Facebook
  • Instagram
  • Youtube
  • LinkedIn

Bangor University

Bangor, Gwynedd, LL57 2DG, UK

+44 (0)1248 351151

Contact Us

Visit Us

Maps & Directions

Policy

  • Legal Compliance
  • Modern Slavery Act 2015 Statement
  • Accessibility Statement
  • Privacy and Cookies
  • Welsh Language Policy
Map

Bangor University is a Registered Charity: No. 1141565

© 2020 Bangor University