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Dr Carlos Lopez-Garcia

Lecturer

c.lopezgarcia@bangor.ac.uk

0000-0001-9848-8216

View Dr Carlos Lopez-Garcia’s profile on the Bangor Research Portal

Qualifications

  • PhD: Involvement of polyamine metabolism in mouse pregnancy
    University of Murcia, 2002–2007
  • BSc: Pharmacy
    University of Valencia, 1995–1998

Postgraduate Project Opportunities

I am willing to supervise a PhD

Publications

2025

  • PublishedA human model to deconvolve genotype-phenotype causations in lung squamous cell carcinoma
    Ogden, J., Sellers, R., Sahoo, S., Oojageer, A., Chaturvedi, A., Dive, C. & Lopez-Garcia, C., 4 Apr 2025, In: Nature Communications. 16, 1, p. 3215
    Research output: Contribution to journal › Article › peer-review

2023

  • PublishedInterrogating the precancerous evolution of pathway dysfunction in lung squamous cell carcinoma using XTABLE
    Roberts, M., Ogden, J., Hossain, A. S. M., Chaturvedi, A., Kerr, A. R. W., Dive, C., Beane, J. E. & Lopez-Garcia, C., 24 Mar 2023, In: Elife. 12
    Research output: Contribution to journal › Article › peer-review

2022

  • PublishedAntizyme Inhibitor 2-Deficient Mice Exhibit Altered Brain Polyamine Levels and Reduced Locomotor Activity
    Lambertos, A., Nuñez-Sanchez, M. A., López-García, C., López-Contreras, A. J., Ramos-Molina, B. & Peñafiel, R., 21 Dec 2022, In: Biomolecules. 13, 1
    Research output: Contribution to journal › Article › peer-review
  • PublishedCEACAM5 is an IL-13-regulated epithelial gene that mediates transcription in type-2 (T2) high severe asthma
    Mumby, S., Kermani, N. Z., Garnett, J. P., Pavlidis, S., Wilson, S. J., Howarth, P. J., Thomas, M. J., Adcock, I. M. & López-García, C., 1 Nov 2022, In: Allergy. 77, 11, p. 3463-3466 4 p.
    Research output: Contribution to journal › Article › peer-review

2018

  • PublishedTolerance of Chromosomal Instability in Cancer: Mechanisms and Therapeutic Opportunities
    Gronroos, E. & López-García, C., 1 Dec 2018, In: Cancer Research. 78, 23, p. 6529-6535 7 p.
    Research output: Contribution to journal › Review article › peer-review

2017

  • PublishedAPC/C Dysfunction Limits Excessive Cancer Chromosomal Instability
    Sansregret, L., Patterson, J. O., Dewhurst, S., López-García, C., Koch, A., McGranahan, N., Chao, W. C. H., Barry, D. J., Rowan, A., Instrell, R., Horswell, S., Way, M., Howell, M., Singleton, M. R., Medema, R. H., Nurse, P., Petronczki, M. & Swanton, C., 5 Feb 2017, In: Cancer discovery. 7, 2, p. 218-233 16 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedBCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer
    López-García, C., Sansregret, L., Domingo, E., McGranahan, N., Hobor, S., Birkbak, N. J., Horswell, S., Grönroos, E., Favero, F., Rowan, A. J., Matthews, N., Begum, S., Phillimore, B., Burrell, R., Oukrif, D., Spencer-Dene, B., Kovac, M., Stamp, G., Stewart, A. & Danielsen, H. & 3 others, Novelli, M., Tomlinson, I. & Swanton, C., 9 Jan 2017, In: Cancer cell. 31, 1, p. 79-93 15 p.
    Research output: Contribution to journal › Article › peer-review

2016

  • PublishedTissue-specific regulation of potassium homeostasis by high doses of cationic amino acids
    Cremades, A., Del Rio-Garcia, J., Lambertos, A., López-Garcia, C. & Peñafiel, R., 13 May 2016, In: SpringerPlus. 5, p. 616
    Research output: Contribution to journal › Article › peer-review

2013

  • PublishedAntizyme inhibitor 2 hypomorphic mice. New patterns of expression in pancreas and adrenal glands suggest a role in secretory processes
    López-Garcia, C., Ramos-Molina, B., Lambertos, A., López-Contreras, A. J., Cremades, A. & Peñafiel, R., 12 Jul 2013, In: PLoS ONE. 8, 7, p. e69188
    Research output: Contribution to journal › Article › peer-review

2010

  • PublishedIntestinal stem cell replacement follows a pattern of neutral drift
    Lopez-Garcia, C., Klein, A. M., Simons, B. D. & Winton, D. J., 5 Nov 2010, In: Science. 330, 6005, p. 822-5 4 p.
    Research output: Contribution to journal › Article › peer-review

2009

  • PublishedTranscriptomic analysis of polyamine-related genes and polyamine levels in placenta, yolk sac and fetus during the second half of mouse pregnancy
    Lopez-Garcia, C., Lopez-Contreras, A. J., Cremades, A., Castells, M. T. & Peñafiel, R., 1 Mar 2009, In: Placenta. 30, 3, p. 241-9 9 p.
    Research output: Contribution to journal › Article › peer-review

2008

  • PublishedMolecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice
    López-García, C., López-Contreras, A. J., Cremades, A., Castells, M. T., Marín, F., Schreiber, F. & Peñafiel, R., Oct 2008, In: Endocrinology. 149, 10, p. 5012-23 12 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedOpposite sexual dimorphism of 3,4-dihydroxyphenylalanine decarboxylase in the kidney and small intestine of mice
    López-Contreras, A. J., Galindo, J. D., López-García, C., Castells, M. T., Cremades, A. & Peñafiel, R., 1 Mar 2008, In: Journal of Endocrinology. 196, 3, p. 615-24 10 p.
    Research output: Contribution to journal › Article › peer-review

2007

  • PublishedSexual dimorphism of ornithine decarboxylase in the mouse adrenal: influence of polyamine deprivation on catecholamine and corticoid levels
    Bastida, C. M., Cremades, A., Castells, M. T., López-Contreras, A. J., López-García, C., Sánchez-Mas, J. & Peñafiel, R., 1 Apr 2007, In: American journal of physiology. Endocrinology and metabolism. 292, 4, p. E1010-7
    Research output: Contribution to journal › Article › peer-review

2006

  • PublishedMouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity
    López-Contreras, A. J., López-Garcia, C., Jiménez-Cervantes, C., Cremades, A. & Peñafiel, R., 13 Oct 2006, In: Journal of Biological Chemistry. 281, 41, p. 30896-906 11 p.
    Research output: Contribution to journal › Article › peer-review

2005

  • PublishedInfluence of ovarian ornithine decarboxylase in folliculogenesis and luteinization
    Bastida, C. M., Cremades, A., Castells, M. T., López-Contreras, A. J., López-García, C., Tejada, F. & Peñafiel, R., 1 Feb 2005, In: Endocrinology. 146, 2, p. 666-74 9 p.
    Research output: Contribution to journal › Article › peer-review

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