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Dr Taher Hatahet

Senior Lecturer

t.hatahet@bangor.ac.uk

0000-0003-0171-3304

Dr Taher Hatahet

View Dr Taher Hatahet’s profile on the Bangor Research Portal

Overview

I am a Syrian-registered pharmacist who completed a Bachelor of Pharmacy degree at the Arab International University in Syria in 2013. Following the receipt of the prestigious Erasmus Mundus Avempace 2 Award from the EU Commission, I began my PhD at the Institute Charles Gerhardt (ICGM) / University of Montpellier, France. My doctoral research, conducted within the Advanced Materials for Health and Catalysis research team, focused on developing novel lipid-based nanoformulations and nanocrystals for the transdermal delivery of antioxidants.

In 2016, I joined the University of Rennes 1, School of Pharmacy, as a Research and Teaching Fellow, where I worked on polymeric nanoparticles for delivering inorganic photosensitizing agents for the theranostic management of ovarian cancer. In May 2018, I joined Queen’s University Belfast School of Pharmacy as a Lecturer in Pharmaceutical Sciences. In 2023, I was promoted to Senior Lecturer, and in April 2025, I joined Bangor University as a Senior Lecturer in Pharmaceutical Technology, where I lead the pharmaceutics development within the MPharm program.

Qualifications

  • Professional: HEA fellowship
    Advance HE, 2020
  • Professional: The Postgraduate Certificate in Higher Education Teaching (PGCHET
    Queen's University, Belfast, 2020
  • PhD: PhD in pharmaceutical technology: Comparison of topical quercetin nanoformulations for skin protection
    Université de Montpellier, 2016

Teaching and Supervision

I teach pharmaceutical sciences and technology components within the MPharm program. Additionally, I engage in pedagogical research aimed at enhancing student engagement and learning through various blended learning approaches. My role extends to administrative responsibilities, including serving as the advisor of studies and others.

Research Interests

My research focuses on developing novel nanomaterials for delivering a broad range of therapeutic agents and fabricating multifunctional nanoparticles to target cancer and other diseases. My long-term goal is to facilitate the translation of nanoparticle-based systems from the lab to the clinic using scalable technologies. I am particularly interested in improving the physiochemical properties of poorly water-soluble drugs to enhance their bioavailability through nanotechnology-based formulations.

My current research themes include:

  1. Lipid-based nano-systems for targeted drug delivery to skin tissue

  2. Nanocrystals for poorly water-soluble drugs

  3. Novel topical therapies for skin cancers and inflammatory skin diseases

Postgraduate Project Opportunities

  • Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery
  • Development of antioxidants-based nanoparticles for topical application
  • Development of next-generation nanoparticles loaded hydrogels containing multiple active agents for improved treatment of bacterial infections
  • Development of anti-inflammatory-based nanoparticles for topical treatment of psoriasis

Publications

2025

  • PublishedBiodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: formulation, in vitro toxicity and in vivo clearance
    Al-Jamal, W. T., Reboredo, C., Abdi, U., Curci, P., Qadadeh, R., Alotaibi, H., Casettari, L. & Hatahet, T., 5 Jan 2025, In: International Journal of Pharmaceutics. 668
    Research output: Contribution to journal › Article › peer-review
  • PublishedDecoding oncogenic secrets of regulator of chromosome condensation 1: A breakthrough mechanistic evidence from breast and lung cancer models
    El-Tanani, M., Satyam, S. M., Rabbani, S. A., Obeidat, R. M., El-Tanani, Y., Aljabali, A. A. A. & Hatahet, T., 31 Mar 2025, In: PLoS ONE. 20, 3
    Research output: Contribution to journal › Article › peer-review
  • PublishedEnhancing the photothermal properties of indocyanine green in melanoma spheroids via encapsulation in Span 80-containing lipid nanocapsules
    Wu, S., Hatahet, T. & Al-Jamal, W. T., 1 May 2025, In: European Journal of Pharmaceutical Sciences. 208, 107049.
    Research output: Contribution to journal › Article › peer-review
  • PublishedEnhancing the photothermal properties of indocyanine green in melanoma spheroids via encapsulation in Span80-containing lipid nanocapsules
    Wu, S., Hatahet, T. & Al-Jamal, W., 1 May 2025, In: European Journal of Pharmaceutical Sciences. 1070409.
    Research output: Contribution to journal › Article › peer-review
  • PublishedIncorporating Span 80 surfactant into lipid nanocapsules improves their biocompatibility and cellular uptake in B16F10 melanoma cells
    Wu, S., Hatahet, T., Bona, B. L., Lodigiani, G., Zhang, M., Baldelli Bombelli, F. & Al-Jamal, W. T., 15 Mar 2025, In: International Journal of Pharmaceutics. 672, 125358.
    Research output: Contribution to journal › Article › peer-review
  • E-pub ahead of printPhytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment
    Aljabali, A. A. A., Obeid, M. A., Bashatwah, R. M., Qnais, E., Gammoh, O., Alqudah, A., Mishra, V., Mishra, Y., Khan, M. A., Parvez, S., El-Tanani, M. & Hatahet, T., 7 Apr 2025, (E-pub ahead of print) In: Chemistry & Biodiversity. e202402479.
    Research output: Contribution to journal › Article › peer-review
  • PublishedScopoletin as a cardioprotective agent against cisplatin-induced oxidative stress and inflammation
    Qnais, E., Gammoh, O., Bsieso, Y., Alqudah, M., Wedyan, M., Altaber, S., Aljabali, A. A. A., Alqudah, A. & Hatahet, T., 1 Feb 2025, In: Phytomedicine Plus.
    Research output: Contribution to journal › Article › peer-review
  • E-pub ahead of printStabilising indocyanine green J-aggregate theranostics in biological milieu via liposomal envelopment
    Alotaibi, H., Hatahet, T. & Al-Jamal, W. T., 14 May 2025, (E-pub ahead of print) In: European Journal of Pharmaceutics and Biopharmaceutics.
    Research output: Contribution to journal › Article › peer-review
  • E-pub ahead of printSupporting active learning opportunities with feedback enhances student achievement in pharmaceutical innovation module: Implication of behavioural and cognitive engagement
    Hatahet, T., 19 Feb 2025, (E-pub ahead of print) In: Social Sciences & Humanities Open. 11, 101347.
    Research output: Contribution to journal › Article › peer-review
  • PublishedUnderstanding the formulation parameters for engineering indocyanine green J-aggregate lipid nanocapsules and solid lipid nanoparticles as promising photothermal agents
    Alotaibi, H., Hatahet, T. & Al-Jamal, W. T., 1 Apr 2025, In: European Journal of Pharmaceutical Sciences. 207, 107034.
    Research output: Contribution to journal › Article › peer-review

2024

  • E-pub ahead of printDevelopment of a tailored educational strategy in primary schools to cope with volatility of education in internally displaced camps: a case study from Northwest Syria
    Hatahet, T., Ekrayem, Z., Badwi, S., Hardan, S., Abdin, A. E. & Alrfooh, O., 17 May 2024, (E-pub ahead of print) In: Vulnerable Children and Youth Studies. p. 1-18 18 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedIndocyanine green J-aggregate (IJA) theranostics: challenges and opportunities
    Alotaibi, H., Hatahet, T. & Al-Jamal, W. T., 15 Aug 2024, In: International Journal of Pharmaceutics. 661
    Research output: Contribution to journal › Article › peer-review
  • PublishedPersonal and engagement factors in remote learning contributing to high student achievement in a transnational education context: A quantitative study
    Hatahet, T., Mohamed, A. A. R., Malekigorji, M., Clerkin, C. & Sandrey, L., 1 Jun 2024, In: Advances in Online Education. 2, 4, p. 330-350 21 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedScopoletin mitigates maternal separation-induced anxiety-like and depression-like behaviors in male mice through modulation of the Sirt1/NF-κB pathway
    Alqudah, A., Qnais, E., Gammoh, O., Bseiso, Y., Wedyan, M., Alqudah, M., Oqal, M., Abudalo, R. & Hatahet, T., 18 Jun 2024, In: Psychopharmacology.
    Research output: Contribution to journal › Article › peer-review

2023

  • PublishedExtracurricular activity based on undergraduates – postgraduates peer learning to promote student’s academic research skills in developing countries higher education: experiences form Syria
    Hatahet, T., Alkhaledi, A., Tello, A., Jarad, L., Al Shihabi, A. & Campbell, K., 20 Sept 2023, In: Educational Research and Evaluation: An International Journal on Theory and Practice. 28, 1-3, p. 42-59 18 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedLiposome-indocyanine green J-aggregates as biodegradable and highly stable photothermal agents for cancer therapy
    Alotaibi, H., Hatahet, T. & Al-Jamal, W., 22 Jun 2023.
    Research output: Contribution to conference › Paper
  • PublishedPhotothermally-activated ICG-loaded lipid nanocapsules (ICG-LNC) for skin cancer.
    Wu, S., Hatahet, T. & Al-Jamal, W., 1 Jun 2023.
    Research output: Contribution to conference › Paper

2022

  • PublishedA global assessment of distance pharmacy education amid COVID-19: teaching, assessment and experiential training
    Alzubaidi, H., Jirjees, F. J., Franson, K. L., Saidawi, W., Othman, A. M., Rabeeah, Z. H., Al Obaidi, H., Hatahet, T. & Caliph, S., 5 Oct 2022, In: International Journal of Pharmacy Practice. 29, 6
    Research output: Contribution to journal › Article › peer-review
  • PublishedChinese students’ perception and expectation of online and post-pandemic teaching and learning approaches in a UK transnational program
    Clerkin, C., Hatahet, T., Malekigorji, M. & Andrews, G. P., 28 Oct 2022, In: Education Sciences. 12, 11, 761.
    Research output: Contribution to journal › Article › peer-review
  • PublishedIndocyanine green J-aggregate (IJA)-loaded lipid nanocapsules as novel photothermal agents
    Alotaibi, H., Hatahet, T. & Al-Jamal, W., 23 Aug 2022.
    Research output: Contribution to conference › Paper
  • PublishedIndocyanine green J-aggregate (IJA)-loaded liposomes as biodegradable photothermal agents
    Alotaibi, H., Hatahet, T. & Al-Jamal, W., 7 Sept 2022.
    Research output: Contribution to conference › Paper
  • PublishedLipid nanocapsules as a versatile platform for drug delivery
    Hatahet, T., Wu, S., Yang, H. & Al-Jamal, W., 7 Sept 2022.
    Research output: Contribution to conference › Paper
  • PublishedOptimising lipid nanocapsules composition to enhance their biocompatibility and IMD loading
    Wu, S., Hatahet, T. & Al-Jamal, W., 9 Sept 2022.
    Research output: Contribution to conference › Paper
  • PublishedRemote learning in transnational education: Engagement with virtual learning environment and student’s perception links to performance in examinations
    Hatahet, T., Mohamed, A. A. R., Malekigorji, M. & Kerry, E., 6 Apr 2022.
    Research output: Contribution to conference › Paper
  • PublishedRemote Learning in Transnational Education: Relationship between Virtual Learning Engagement and Student Academic Performance in BSc Pharmaceutical Biotechnology
    Hatahet, T., Mohamed, A. A. R., Malekigorji, M. & Kerry, E., 1 Feb 2022, In: Pharmacy. 10, 1
    Research output: Contribution to journal › Article › peer-review
  • PublishedRisk assessment of the continuity of essential medications for low socioeconomic patients in Syria: a case study of diabetes mellitus Open Access
    Sahloul, L., Bouri, F., Bsso, E., Saleh, A., Darwish , E., Yaseen, L., Muhamed Mustafa, A. & Hatahet, T., 27 Sept 2022, In: Journal of Pharmaceutical Health Services Research. p. 364-369 13.
    Research output: Contribution to journal › Article › peer-review
  • PublishedStrategic job market-guided development of pharmacy bachelor‘s curriculum and its importance in maintaining the profession viability in the Middle Eastern countries: Colleges of pharmacy in the UAE as a model
    Hatahet, T., Al Obaidi, H., Tekko, I. A. & Chen, T., 1 Sept 2022, In: Saudi Pharmaceutical Journal. 30, 9, p. 1283-1292
    Research output: Contribution to journal › Article › peer-review

2021

  • PublishedCOVID-19 Treatment Guidelines: Do They Really Reflect Best Medical Practices to Manage the Pandemic?
    Jirjees, F. J., Saad, A. K., Al Hano, Z., Hatahet, T., Al Obaidi, H. & Dallal Bashi, Y. H., 1 Apr 2021, In: Infectious Disease Reports. 13, 2
    Research output: Contribution to journal › Article › peer-review

2020

  • PublishedClassroom Response System in a Super-Blended Learning and Teaching Model: Individual or Team-Based Learning?
    Malekigorji, M. & Hatahet, T., 24 Oct 2020, In: Pharmacy. 8, 4
    Research output: Contribution to journal › Article › peer-review
  • PublishedLocalised and sustained intradermal delivery of methotrexate using nanocrystal-loaded microneedle arrays: Potential for enhanced treatment of psoriasis
    Tekko, I. A., Permana , A. D., Vora , L., Hatahet, T., McCarthy , H. O. & Donnelly , R. F., 1 Sept 2020, In: European Journal of Pharmaceutical Sciences. 152, 105469.
    Research output: Contribution to journal › Article › peer-review

2019

  • PublishedBuilding blended learning models by using different learning technologies: Evidence from a 4-year study
    Malekigorji, M. & Hatahet, T., 2019.
    Research output: Contribution to conference › Paper
  • PublishedImproving classroom engagement by embedding personal response system in flipped classroom teaching strategy
    Malekigorji, M. & Hatahet, T., 2019.
    Research output: Contribution to conference › Poster
  • PublishedMaximising Your Environment By The Application Of Blended Classroom Response System
    Hatahet, T. & Malekigorji, M., 2019.
    Research output: Contribution to conference › Paper
  • PublishedPolyethylene Glycol-Based Solid Dispersions to Enhance Eprosartan Mesylate Dissolution and Bioavailability
    Tekko, I. A., Ali, O. M., Hatahet, T. & Chehna, M. F., 7 Nov 2019, In: Archives of Pharmacy & Pharmacology Research. 2, 3
    Research output: Contribution to journal › Article › peer-review

2018

  • PublishedLiposomes, lipid nanocapsules and smartCrystals®: A comparative study for an effective quercetin delivery to the skin
    Hatahet, T., Morille, M., Hommoss, A., Devoisselle, J. M., Muller , R. & Begu, S., 5 May 2018, In: International Journal of Pharmaceutics. 542, 1-2, p. 176-185
    Research output: Contribution to journal › Article › peer-review
  • PublishedMolybdenum cluster loaded PLGA nanoparticles: An innovative theranostic approach for the treatment of ovarian cancer
    Hatahet, T., Brandhonneura, N., Amela-Cortes, M., Molard, Y., Cordier, S. & Dolloa, G., 1 Apr 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 125, p. 95-105
    Research output: Contribution to journal › Article › peer-review

2017

  • PublishedDermal quercetin lipid nanocapsules: Influence of the formulation on antioxidant activity and cellular protection against hydrogen peroxide
    Hatahet, T., Morille, M., Shamseddin, A., Aubert-Pouëssel, A., Devoisselle, J. M. & Begu, S., 25 Feb 2017, In: International Journal of Pharmaceutics. 518, 1-2
    Research output: Contribution to journal › Article › peer-review

2016

  • PublishedDermal quercetin smartCrystals®: Formulation development, antioxidant activity and cellular safety
    Hatahet, T., Morille, M., Hommoss, A., Dorandeu, C., Muller , R. & Begu, S., 1 May 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 102, p. 51-63
    Research output: Contribution to journal › Article › peer-review
  • PublishedQuercetin topical application, from conventional dosage forms to nanodosage forms
    Hatahet, T., Morille, M., Hommoss, A., Devoisselle, J. M., Muller , R. & Begu, S., 1 Nov 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 108, p. 41-53
    Research output: Contribution to journal › Article › peer-review

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