• PhD: Tumour suppressor regulation of tumour immune interactions in lung adenocarcinoma
  Barts and the London School of Medicine and Dentistry, 2017–2020

Module MSE-4041: Human Immunology & Disease

Module MSE-4042: Laboratory Molecular Research

The Kennedy group is focused on molecular pathways which govern epithelial-immune cell interactions, specifically in the context of tumour microenvironments and autoinflammatory disorders. Effective immune tolerance is essential for tissue homeostasis and is frequently compromised in the pathogenesis of autoimmunity and cancer. We aim to study the molecular immunology of disease mechanisms with the ultimate goal of identifying new opportunities for immunotherapy.

I am willing to supervise a PhD

2025

• PublishedCTLA-4-two pathways to anti-tumour immunity?
  Ward, F. J., Kennedy, P. T., Al-Fatyan, F., Dahal, L. N. & Abu-Eid, R., 22 Apr 2025, In: Immunotherapy advances. 5, 1, ltaf008.
  Research output: Contribution to journal › Review article › peer-review

2024

• PublishedDifferential Regulation of the STING Pathway in Human Papillomavirus-Positive and -Negative Head and Neck Cancers
  Saulters, E. L., Kennedy, P. T., Carter, R. J., Alsufyani, A., Jones, T. M., Woolley, J. F. & Dahal, L. N., 16 Jan 2024, In: Cancer research communications. 4, 1, p. 118-133 16 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedSoluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity
  Kennedy, P. T., Saulters, E. L., Duckworth, A. D., Lim, Y. J., Woolley, J. F., Slupsky, J. R., Cragg, M. S., Ward, F. J. & Dahal, L. N., 7 Feb 2024, In: Molecular therapy : the journal of the American Society of Gene Therapy. 32, 2, p. 457-468 12 p.
  Research output: Contribution to journal › Article › peer-review

2023

• PublishedNeuroblastoma: an ongoing cold front for cancer immunotherapy
  Kennedy, P. T., Zannoupa, D., Son, M. H., Dahal, L. N. & Woolley, J. F., 22 Nov 2023, In: Journal for immunotherapy of cancer. 11, 11, e007798.
  Research output: Contribution to journal › Review article › peer-review

2021

• PublishedInvestigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review
  Wells, G., Kennedy, P. T. & Dahal, L. N., 10 Mar 2021, In: Frontiers in immunology. 12, 651687.
  Research output: Contribution to journal › Article › peer-review
• PublishedZinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation
  Rivers-Auty, J., Tapia, V. S., White, C. S., Daniels, M. J. D., Drinkall, S., Kennedy, P. T., Spence, H. G., Yu, S., Green, J. P., Hoyle, C., Cook, J., Bradley, A., Mather, A. E., Peters, R., Tzeng, T.-C., Gordon, M. J., Beattie, J. H., Brough, D. & Lawrence, C. B., 31 Mar 2021, In: Journal of Neuroscience. 41, 13, p. 3025-3038 14 p.
  Research output: Contribution to journal › Article › peer-review

2018

• PublishedA HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia
  Foxler, D. E., Bridge, K. S., Foster, J. G., Grevitt, P., Curry, S., Shah, K. M., Davidson, K. M., Nagano, A., Gadaleta, E., Rhys, H. I., Kennedy, P. T., Hermida, M. A., Chang, T.-Y., Shaw, P. E., Reynolds, L. E., McKay, T. R., Wang, H.-W., Ribeiro, P. S., Plevin, M. J. & Lagos, D. & 7 others, Lemoine, N. R., Rajan, P., Graham, T. A., Chelala, C., Hodivala-Dilke, K. M., Spendlove, I. & Sharp, T. V., Aug 2018, In: EMBO molecular medicine. 10, 8, 18 p., e8304.
  Research output: Contribution to journal › Article › peer-review