• PhD: Tumour suppressor regulation of tumour immune interactions in lung adenocarcinoma
  Barts and the London School of Medicine and Dentistry, 2017–2020

Module MSE-4041: Human Immunology & Disease

Module MSE-4042: Laboratory Molecular Research

The Kennedy group is focused on molecular pathways which govern epithelial-immune cell interactions, specifically in the context of tumour microenvironments and autoinflammatory disorders. Effective immune tolerance is essential for tissue homeostasis and is frequently compromised in the pathogenesis of autoimmunity and cancer. We aim to study the molecular immunology of disease mechanisms with the ultimate goal of identifying new opportunities for immunotherapy.

’Rydwyf yn fodlon goruchwylio cwrs PhD

2025

• CyhoeddwydCTLA-4-two pathways to anti-tumour immunity?
  Ward, F. J., Kennedy, P. T., Al-Fatyan, F., Dahal, L. N. & Abu-Eid, R., 22 Ebr 2025, Yn: Immunotherapy advances. 5, 1, ltaf008.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid
• CyhoeddwydInfluence of polyfunctional Tbet+ T cells on specific clinical events in chronic lymphocytic leukaemia
  Lim, Y. J., Duckworth, A. D., Clarke, K., Kennedy, P., Karpha, I., Oates, M., Gornall, M., Kalakonda, N., Slupsky, J. R. & Pettitt, A. R., 17 Ebr 2025, Yn: Frontiers in immunology. 16, 1528405.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
• CyhoeddwydMass Cytometry-Based Approach for the Investigation of Stimulator of Interferon Genes Pathway
  Reversat, A., Kennedy, P. T., Georghiou, A., Slupsky, J. R. & Dahal, L. N., 18 Rhag 2025, Yn: European Journal of Immunology. 55, 12, t. e70101
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2024

• CyhoeddwydDifferential Regulation of the STING Pathway in Human Papillomavirus-Positive and -Negative Head and Neck Cancers
  Saulters, E. L., Kennedy, P. T., Carter, R. J., Alsufyani, A., Jones, T. M., Woolley, J. F. & Dahal, L. N., 16 Ion 2024, Yn: Cancer research communications. 4, 1, t. 118-133 16 t.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
• CyhoeddwydSoluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity
  Kennedy, P. T., Saulters, E. L., Duckworth, A. D., Lim, Y. J., Woolley, J. F., Slupsky, J. R., Cragg, M. S., Ward, F. J. & Dahal, L. N., 7 Chwef 2024, Yn: Molecular therapy : the journal of the American Society of Gene Therapy. 32, 2, t. 457-468 12 t.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2023

• CyhoeddwydNeuroblastoma: an ongoing cold front for cancer immunotherapy
  Kennedy, P. T., Zannoupa, D., Son, M. H., Dahal, L. N. & Woolley, J. F., 22 Tach 2023, Yn: Journal for immunotherapy of cancer. 11, 11, e007798.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl adolygu › adolygiad gan gymheiriaid

2021

• CyhoeddwydInvestigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review
  Wells, G., Kennedy, P. T. & Dahal, L. N., 10 Maw 2021, Yn: Frontiers in immunology. 12, 651687.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
• CyhoeddwydZinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation
  Rivers-Auty, J., Tapia, V. S., White, C. S., Daniels, M. J. D., Drinkall, S., Kennedy, P. T., Spence, H. G., Yu, S., Green, J. P., Hoyle, C., Cook, J., Bradley, A., Mather, A. E., Peters, R., Tzeng, T.-C., Gordon, M. J., Beattie, J. H., Brough, D. & Lawrence, C. B., 31 Maw 2021, Yn: Journal of Neuroscience. 41, 13, t. 3025-3038 14 t.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

2018

• CyhoeddwydA HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia
  Foxler, D. E., Bridge, K. S., Foster, J. G., Grevitt, P., Curry, S., Shah, K. M., Davidson, K. M., Nagano, A., Gadaleta, E., Rhys, H. I., Kennedy, P. T., Hermida, M. A., Chang, T.-Y., Shaw, P. E., Reynolds, L. E., McKay, T. R., Wang, H.-W., Ribeiro, P. S., Plevin, M. J. & Lagos, D. & 7 eraill, Lemoine, N. R., Rajan, P., Graham, T. A., Chelala, C., Hodivala-Dilke, K. M., Spendlove, I. & Sharp, T. V., Awst 2018, Yn: EMBO molecular medicine. 10, 8, 18 t., e8304.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid