Giovanna is a Research Fellow in Pharmaco-economics at the Centre for Health Economics and Medicine Evaluation.

Prior to joining CHEME, Giovanna served Manchester City Council as a researcher. She holds a MSc in Research Methods and Statistics from the University of Manchester and a MA degree in International Development: poverty, conflict and reconstruction from the University of Manchester. Giovanna's training has primarily been in  quantitative researche methods.

Giovanna joined CHEME in 2015. Since then she has been appointed as the Health Economist of a variety of research projects and randomised controlled trials. These research led to several publications in prestigious journals icluding LANCET, and Journal of Neurology, Neurosurgery and Psychiatry.

Giovanna is undertaking a PhD in Pharmaco-economics as a staff candidate. Her thesis explores the applicability of different statistical methods (frequentist approach versus Bayesian) in the context of trial-based cost effectiveness analyses.

Apart from her research endeavors, Giovanna participates in professional societies and groups. She is a member of the Royal Statistical Society (RSS), the Health Economics Study Group (HESG), the European Respiratory Society (ERS), and the Health Technology Assessment International Society (HTAi). Further showcasing her commitment to her field, Giovanna represents the Early Career Researchers (ECR) for the School.

Ardudwy

Normal Site

Bangor University

Holyhead Road

Bangor

Wales

LL57 2PZ

e-mail: g.culeddu@bangor.ac.uk

Tel: +44 (0)1248 388439

Web: http://cheme.bangor.ac.uk

• MSc: Social Research Methods and Statistics
  University of Manchester, 2015
• MA: MA International Development: poverty, conflict and reconstruction
  University of Manchester, 2008

2025

• PublishedEstablishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data
  Cividini, S., Sinha, I., Culeddu, G., Donegan, S., Maden, M., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 15 May 2025, In: Health Technology Assessment. 29, 15, p. 1-234 234 p.
  Research output: Contribution to journal › Article › peer-review

2024

• PublishedEconomic analysis of treatments for children who do not achieve adequate asthma control when using low-dose inhaled corticosteroids
  Culeddu, G., Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Turner, S., Smith, C. T. & Hughes, D., 30 Jul 2024, In: Disease in Childhood. 109, suppl 1
  Research output: Contribution to journal › Conference article › peer-review

2023

• PublishedA “Bundle of Care” to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study
  Jorgensen, A., Waitt, C., Orrell, C., Cheng-Hock, T., Sekaggya-Wiltshire, C., Hughes, D., Allen, E., Okello, E., Tatz, G., Culeddu, G., Asiimwe, I. G., Semakula, J. R., Mouton, J. P., Cohen, K., Blockman, M., Lamorde, M. & Pirmohamed, M., 19 Jul 2023, In: Journal of Medical Internet Research. 12, e46710.
  Research output: Contribution to journal › Article › peer-review
• PublishedBest step-up treatments for children with uncontrolled asthma: A systematic review and network meta-analysis of individual participant data
  Cividini, S., Sinha, I., Donegan, S., Maden, M., Rose, K., Fulton, O., Culeddu, G., Hughes, D., Turner, S. & Tudor-Smith, C., 21 Dec 2023, In: European Respiratory Journal. 62, 6, 2301011.
  Research output: Contribution to journal › Article › peer-review
• PublishedCost effectiveness analysis of treatments for children with uncontrolled asthma symptoms despite taking inhaled corticosteroids
  Culeddu, G., Sinha, I., Donegan, S., Maden, M., Cividini, S., Rose, K., Fulton, O., Turner, S., Tudor-Smith, C. & Hughes, D., 27 Oct 2023, In: European Respiratory Journal. 62 , Supplement 67, PA 523.
  Research output: Contribution to journal › Meeting Abstract › peer-review

2022

• PublishedNovel oral iron therapy for iron deficiency anaemia: How to value safety in a new drug?
  Culeddu, G., Su, L., Chen, Y., Pereira, D. I. A., Powell, J. J. & Hughes, D., Mar 2022, In: British Journal of Clinical Pharmacology. 88, 3, p. 1347-1357 11 p.
  Research output: Contribution to journal › Article › peer-review

2021

• PublishedCost-Effectiveness Analysis of Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa
  Culeddu, G., Brogan, P. A. & Hughes, D., 2021.
  Research output: Contribution to conference › Other › peer-review
• PublishedEstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): Protocol for a systematic review, network meta-analysis and cost-effectiveness analysis using individual participant data (IPD)
  Cividini, S., Sinha, I., Donegan, S., Maden, M., Culeddu, G., Rose, K., Fulton, O., Hughes, D., Turner, S. & Smith, C. T., 5 Feb 2021, In: BMJ Open. 11, e040528.
  Research output: Contribution to journal › Article › peer-review
• PublishedMycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open-Label, Randomized, Bayesian Noninferiority Trial
  Brogan, P. A., Arch, B., Hickey, H., Anton, J., Iglesias, E., Baildam, E., Mahmood, K., Cleary, G., Moraitis, E., Papadopoulou, C., Beresford, M. W., Riley, P., Demir, S., Ozen, S., Culeddu, G., Hughes, D., Dolezalova, P., Hampson, L., Whitehead, J. & Jayne, D. & 3 others, Ruperto, N., Tudor-Smith, C. & Eleftheriou, D., Sept 2021, In: Arthritis and Rheumatology. 73, 9, p. 1673-1682
  Research output: Contribution to journal › Article › peer-review

2020

• PublishedSilver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT
  Mallucci, C. L., Jenkinson, M., Conroy, E. J., Hartley, J. C., Brown, M., Moitt, T., Dalton, J., Kearns, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 2 Apr 2020, In: Health Technology Assessment. 24, 17, 114 p.
  Research output: Contribution to journal › Article › peer-review

2019

• PublishedAdalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT
  Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D., McKay, A., Rosala_Hanna, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Eldesten, C. & Beresford, M. W., 10 Apr 2019, In: Health Technology Assessment. 23, 15, p. 1-174 174 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedAntibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multi-centre, single-blinded, randomised trial and economic evaluation
  Mallucci, C. L., Jenkinson, M. D., Conroy, E. J., Hartley, J. C., Brown, M., Dalton, J., Kearns, T., Moitt, T., Griffiths, M. J., Culeddu, G., Solomon, T., Hughes, D. & Gamble, C., 26 Oct 2019, In: The Lancet. 394, 10208, p. 1530-1539 10 p.
  Research output: Contribution to journal › Article › peer-review
• PublishedCost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis
  Hughes, D. A., Culeddu, G., Plumpton, C. O., Wood, E., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. 415-424
  Research output: Contribution to journal › Article › peer-review
• PublishedCost-effectiveness analysis of adalimumab for the treatment of uveitis associated with Juvenile Idiopathic Arthritis: Authors’ reply.
  Hughes, D., Culeddu, G., Plumpton, C., Wood, E., Dick, A. D., Beresford, M. W. & Ramanan, A. V., Mar 2019, In: Ophthalmology. 126, 3, p. e24-e25
  Research output: Contribution to journal › Letter › peer-review

2018

• PublishedLetter to the Editor. Phase III randomized controlled trials are essential to properly evaluate the role of radiotherapy in WHO grade II meningioma
  Jenkinson, M., Weber, D., Haylock, B., Sherratt, F., Young, B., Weller, M., Bulbeck, H., Culeddu, G., Hughes, D., Brain, A., Das, K., Preusser, M., Francis, P. & Gamble, C., 17 Aug 2018, In: Journal of Neurology, Neurosurgery and Psychiatry.
  Research output: Contribution to journal › Letter › peer-review

2017

• PublishedComparison of regression methods for the cost effectiveness analysis of clinical trials with a small population size: the sycamore and folated trials
  Culeddu, G., Hughes, D. & Welton, N., 10 Jul 2017.
  Research output: Contribution to conference › Poster › peer-review

2024

• Public engagement in health economics: CHEME at the Bangor Science Festival.

  As part of Bangor Science Festival, researchers from CHEME invited visitors to explore the world of health economics through interactive activities and discussions. Attendees engaged in hands-on exercises designed to illustrate key economic concepts such as cost-effectiveness, resource allocation, and healthcare decision-making. The session encouraged children and their parents to think about the challenges of balancing NHS costs through engaging and accessible activities.

  9 Mar 2024

  Links:

  • https://www.bangor.ac.uk/cy/gwyl-wyddoniaeth-bangor
  • https://www.bangor.ac.uk/bangor-science-festival
  Activity: Types of Public engagement and outreach - Festival/Exhibition (Contributor)

2023

• Public engagement in health economics: CHEME at the Bangor University's Community Day.

  As part of Bangor University’s Community Day, researchers from CHEME engaged the public in an interactive exploration of health economics. Visitors of all ages participated in activities designed to highlight key economic concepts, such as resource allocation, cost-effectiveness, and healthcare prioritisation. Through hands-on exercises and discussions, attendees gained insights into the challenges of balancing NHS costs and patient needs.

  14 Oct 2023

  Links:

  • https://www.bangor.ac.uk/cy/diwrnod-cymunedol-prifysgol-bangor
  • https://www.bangor.ac.uk/bangor-university-community-day
  Activity: Types of Public engagement and outreach - Festival/Exhibition (Contributor)

2021

• Health Technology Assessment International Society (External organisation)

  23 Mar 2021

  Activity: Membership of network (Member)
• Health Economists' Study Group (External organisation)

  5 Mar 2021

  Activity: Membership of network (Member)

2016

• The Royal Statistical Society (External organisation)

  1 Jan 2016

  Activity: Membership of network (Member)