Postgraduate Project Opportunities
Radiochemistry; Radionuclide modelling; Radiobiology;
Publications
2024
- PublishedA hypoxia biomarker does not predict benefit from giving chemotherapy with radiotherapy in the BC2001 randomised controlled trial
Smith, T., West, C., Joseph, N., Lane, B., Irlam-Jones, J., More, E., Mistry, H., Reeves, K., Song, Y. P., Reardon, M., Hoskin, P., Hussain, S., Denley, H., Hall, E., Porta, N., Huddart, R., James, N. & Choudhury, A., 1 Mar 2024, In: eBioMedicine. 101, p. 105032 14 p., 105032.
Research output: Contribution to journal › Article › peer-review - E-pub ahead of printCRISPR–Cas9 potential for identifying novel therapeutic targets in muscle-invasive bladder cancer
Smith, D., Lunj, S., Adamson, A., Nagarajan, S., Smith, T., Reeves, K., Hoskin, P. & Choudhury, A., 1 Jul 2024, (E-pub ahead of print) In: Nature Reviews Urology. 21, 11 p.
Research output: Contribution to journal › Article › peer-review - PublishedGene Abnormalities and Modulated Gene Expression Associated with Radionuclide Treatment: Towards Predictive Biomarkers of Response
Smith, T., 26 May 2024, In: Genes. 15, 6, p. 688 16 p., 15060688.
Research output: Contribution to journal › Review article › peer-review - PublishedHypoxia-associated gene signatures are not prognostic in high-risk localised prostate cancers undergoing androgen deprivation therapy with radiotherapy
Reardon, M., Bibby, B., Thiruthaneeswaran, N., Pereira, R., Mistry, H., More, E., Tsang, Y., Vickers, A., Reeves, K., Hendry, A., Denley, H., Wyley, J., Sprat, D., Hakansson, A., Ryu, M., Smith, T., Hoskin, P., Bristow, R., Choudhury, A. & West, C., 2024, In: international journal of Radiation Oncology Biology Physics. 121, 3, p. 752-760
Research output: Contribution to journal › Article › peer-review - E-pub ahead of printImmune effects of α and β radionuclides in metastatic prostate cancer
Lunj, S., Smith, T., Reeves, K., Currell, F., Honeychurch, J., Hoskin, P. & Choudhury, A., 27 Aug 2024, (E-pub ahead of print) In: Nature Reviews Urology. 11 p.
Research output: Contribution to journal › Review article › peer-review - PublishedImplementation of Oxygen Enhanced Magnetic Resonance Imaging (OE-MRI) and a Pilot Genomic Study of Hypoxia in Bladder Cancer Xenografts
Shabbir, R., Telfer, B., Dickie, B., Reardon, M., Babur, M., Williams, K., Choudhury, A., West, C. & Smith, T., 27 Jun 2024, In: Cancer Genomics & Proteomics. 21, 4, p. 380-387 8 p.
Research output: Contribution to journal › Article › peer-review - PublishedModelling Potential Candidates for Targeted Auger Therapy
Buchanan, C., Aboagye, E., Evitts, L. J., Rushton, M. & Smith, T., 18 Dec 2024, In: Biophysica. 4, p. 711-723 13 p.
Research output: Contribution to journal › Article › peer-review
2022
- E-pub ahead of printComparison of multiple gene expression platforms for measuring a bladder cancer hypoxia signature
Smith, T., Lane, B., More, E., Valentine, H., Lunj, S., Abdelkarem, O., Irlam-Jones, J., Shabbir, R., Denley, H., Reeves, K., Hoskin, P., Choudhury, A. & West, C., 20 Jun 2022, (E-pub ahead of print) In: Molecular Medicine Reports. 26, 2, 8 p., 261.
Research output: Contribution to journal › Article › peer-review
2021
- PublishedEGFR targeting of [177Lu] gold nanoparticles to colorectal and breast tumour cells: Affinity, duration of binding and growth inhibition of Cetuximab-resistant cells
Shabbir, R., Mingarelli, M., Cabello, G., Van Herk, M., Choudhury, A. & Smith, T., 7 Oct 2021, In: Journal of King Saud University-Science. 33, 7, 8 p., 101573.
Research output: Contribution to journal › Article › peer-review
Activities
2025
- Medical Radionuclide work at Bangor
May 2025
Activity: Oral presentation (Speaker)
2024
- Gene expression based biomarkers and radiopharmaceutical therapy
Dec 2024
Activity: Invited talk (Speaker) - Synthons for the site-specific radiolabeling of histagged proteins with 99mTc/186/188Re.
PhD External Examiner
Dec 2024
Activity: Examination (Examiner) - Royal College of Radiologists, Fellow of Royal College of Radiologist part 1
Lecturer
Nov 2024
Activity: Participation in Academic workshop, seminar, course (Speaker) - Development of Peptide Based Positron Emission Tomography Radiopharmaceuticals with Gallium-68
MSc external examiner
May 2024
Activity: Examination (Examiner) - Understanding the role of different versican isoforms in regulating the proliferation and function of fibroblasts in pancreatic cancer
PhD external examiner
Apr 2024
Activity: Examination (Examiner)