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Dr Tim Smith

Senior Lecturer

tim.smith@bangor.ac.uk

+44 1248 382664

0000-0002-3945-630X

View Dr Tim Smith’s profile on the Bangor Research Portal

Postgraduate Project Opportunities

Radiochemistry; Radionuclide modelling; Radiobiology;

Publications

2025

  • PublishedApparatus and Experiments Towards Fully Automated Medical Isotope Production Using an Ion Beam Accelerator
    Hussain, A. Y. M., Baidak, A., Choudhury, A., Smith, A., Andrews, C., Wojcik, E., Brown, L., Nancekievill, M., De Moraes Shubeita, S., Smith, T. A. D., Yasakci, V. & Currell, F., 18 Jul 2025, In: Instruments. 9, 3, 18.
    Research output: Contribution to journal › Article › peer-review
  • PublishedCell Surface Proteomics Reveals Hypoxia-Regulated Pathways in Cervical and Bladder Cancer
    Alanazi, F., Sharif, A., Kidd, M., Keevill, E., Unwin, R., Hoskin, P., Choudhury, A., Smith, T. A. D. & Quiles, C., 5 Aug 2025, In: Proteomes. 13, 3, 18 p., 36.
    Research output: Contribution to journal › Article › peer-review
  • PublishedGene Expression in Muscle-Invasive and Non-Muscle-Invasive Bladder Cancer Cells Exposed to Hypoxia
    Shabbir, R., Quiles, C., Lane, B., Zeef, L., Hoskin, P., Choudhury, A., West, C. & Smith, T. A. D., 11 Aug 2025, In: Cancers. 17, 19 p., 2624.
    Research output: Contribution to journal › Article › peer-review

2024

  • PublishedA hypoxia biomarker does not predict benefit from giving chemotherapy with radiotherapy in the BC2001 randomised controlled trial
    Smith, T., West, C., Joseph, N., Lane, B., Irlam-Jones, J., More, E., Mistry, H., Reeves, K., Song, Y. P., Reardon, M., Hoskin, P., Hussain, S., Denley, H., Hall, E., Porta, N., Huddart, R., James, N. & Choudhury, A., 1 Mar 2024, In: eBioMedicine. 101, p. 105032 14 p., 105032.
    Research output: Contribution to journal › Article › peer-review
  • E-pub ahead of printCRISPR–Cas9 potential for identifying novel therapeutic targets in muscle-invasive bladder cancer
    Smith, D., Lunj, S., Adamson, A., Nagarajan, S., Smith, T., Reeves, K., Hoskin, P. & Choudhury, A., 1 Jul 2024, (E-pub ahead of print) In: Nature Reviews Urology. 21, 11 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedGene Abnormalities and Modulated Gene Expression Associated with Radionuclide Treatment: Towards Predictive Biomarkers of Response
    Smith, T., 26 May 2024, In: Genes. 15, 6, p. 688 16 p., 15060688.
    Research output: Contribution to journal › Review article › peer-review
  • PublishedHypoxia-associated gene signatures are not prognostic in high-risk localised prostate cancers undergoing androgen deprivation therapy with radiotherapy
    Reardon, M., Bibby, B., Thiruthaneeswaran, N., Pereira, R., Mistry, H., More, E., Tsang, Y., Vickers, A., Reeves, K., Hendry, A., Denley, H., Wyley, J., Sprat, D., Hakansson, A., Ryu, M., Smith, T., Hoskin, P., Bristow, R., Choudhury, A. & West, C., 2024, In: international journal of Radiation Oncology Biology Physics. 121, 3, p. 752-760
    Research output: Contribution to journal › Article › peer-review
  • E-pub ahead of printImmune effects of α and β radionuclides in metastatic prostate cancer
    Lunj, S., Smith, T., Reeves, K., Currell, F., Honeychurch, J., Hoskin, P. & Choudhury, A., 27 Aug 2024, (E-pub ahead of print) In: Nature Reviews Urology. 11 p.
    Research output: Contribution to journal › Review article › peer-review
  • PublishedImplementation of Oxygen Enhanced Magnetic Resonance Imaging (OE-MRI) and a Pilot Genomic Study of Hypoxia in Bladder Cancer Xenografts
    Shabbir, R., Telfer, B., Dickie, B., Reardon, M., Babur, M., Williams, K., Choudhury, A., West, C. & Smith, T., 27 Jun 2024, In: Cancer Genomics & Proteomics. 21, 4, p. 380-387 8 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedModelling Potential Candidates for Targeted Auger Therapy
    Buchanan, C., Aboagye, E., Evitts, L. J., Rushton, M. & Smith, T., 18 Dec 2024, In: Biophysica. 4, p. 711-723 13 p.
    Research output: Contribution to journal › Article › peer-review

2022

  • E-pub ahead of printComparison of multiple gene expression platforms for measuring a bladder cancer hypoxia signature
    Smith, T., Lane, B., More, E., Valentine, H., Lunj, S., Abdelkarem, O., Irlam-Jones, J., Shabbir, R., Denley, H., Reeves, K., Hoskin, P., Choudhury, A. & West, C., 20 Jun 2022, (E-pub ahead of print) In: Molecular Medicine Reports. 26, 2, 8 p., 261.
    Research output: Contribution to journal › Article › peer-review

2021

  • PublishedEGFR targeting of [177Lu] gold nanoparticles to colorectal and breast tumour cells: Affinity, duration of binding and growth inhibition of Cetuximab-resistant cells
    Shabbir, R., Mingarelli, M., Cabello, G., Van Herk, M., Choudhury, A. & Smith, T., 7 Oct 2021, In: Journal of King Saud University-Science. 33, 7, 8 p., 101573.
    Research output: Contribution to journal › Article › peer-review

Activities

2025

  • What is Nuclear Medicine?

    Outreach: Talk on nuclear medicine 40 UK chemistry teachers organised by the Royal Society of Chemistry

    17 Jun 2025

    Activity: Invited talk (Speaker)
  • Medical Radionuclide work at Bangor

    May 2025

    Activity: Oral presentation (Speaker)

2024

  • Gene expression based biomarkers and radiopharmaceutical therapy

    Dec 2024

    Activity: Invited talk (Speaker)
  • Synthons for the site-specific radiolabeling of histagged proteins with 99mTc/186/188Re.

    PhD External Examiner

    Dec 2024

    Activity: Examination (Examiner)
  • Royal College of Radiologists, Fellow of Royal College of Radiologist part 1

    Lecturer

    Nov 2024

    Activity: Participation in Academic workshop, seminar, course (Speaker)
  • Development of Peptide Based Positron Emission Tomography Radiopharmaceuticals with Gallium-68

    MSc external examiner

    May 2024

    Activity: Examination (Examiner)
  • Understanding the role of different versican isoforms in regulating the proliferation and function of fibroblasts in pancreatic cancer

    PhD external examiner

    Apr 2024

    Activity: Examination (Examiner)

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