Run by School of Medical and Health Sciences

30.000 Credits or 15.000 ECTS Credits

Semester 1 & 2

Organiser: Mrs Bethan Davies Jones

This module is designed to enable students to acquire Masters level knowledge and understanding of the field of Cellular and Molecular Pathology. The module will facilitate a deeper understanding of the classical role of histology in the identification of disease and how modern molecular methodologies can supplement these classic methodologies. Students will also undertake to learn the role cell and molecular pathology also have in therapeutic management of patients by studying the role of the discipline in detecting drug sensitivies and/or resistance in diseases such as cancer.

This module will explore the role of diagnostic science in the identification and treatment of neoplasia within humans. We will also look at the role of inflammation and how this can manifest itself as chronic disease. The techniques this module will discuss include histochemical methodolgoies and molecular methodologies such as immunohistochemistry, DNA amplification and in-situ hybridization.

threshold

Primary criteria

A threshold student demonstrates knowledge of key areas & principles, and understands the main elements of the subject area, although gaps and weaknesses in the argument are evident. No evidence of background study and wider reading. Answer focussed on question but also with some irrelevant material and weaknesses in structure & argument. Answers have several factual/computational errors. No original interpretation. No links between topics are described. Limited problem solving skills. Some weaknesses in presentation accuracy & delivery.

Secondary Criteria

C+ Good within the class

Exceeds expectations for some primary criteria Strong factual knowledge with some weaknesses in understanding Ideas/arguments are limited but are well presented

C Mid-level

Matches all primary criteria Moderate factual knowledge with some weaknesses in understanding Ideas/arguments are limited presented with weaknesses in logic/presentation

C- Meets requirements of class

Matches most but not all primary criteria Moderate factual knowledge with several weaknesses in understanding Ideas/arguments are limited presented with weaknesses in logic/presentation

good

Primary criteria

Good students demonstrate strong knowledge & understanding of most but not all of the subject area. Limited evidence of background study. The answer is focussed with good structure. Arguments are presented coherently, mostly free of factual/computational errors. Some limited original interpretation. Well know links between topics are described. Problems are addressed by existing methods/approaches. Good presentation with accurate communication

Secondary Criteria

B+ Good

Exceeds expectations for most primary criteria Command of subject but with gaps in knowledge Some ideas/arguments original

B Mid-level

Meets all primary criteria Strong factual knowledge and understanding Ideas/arguments are well presented by few are original

B- Meets requirements of class

Meets most but not all primary criteria Strong factual knowledge with minor weaknesses in understanding Most but not all ideas/arguments are well presented and few are original

excellent

Primary criteria

Comprehensive knowledge & detailed understanding. Clear evidence of extensive background study & originality. Highly focussed, relevant and well structured answers. Arguments logically presented and defended with evidence and examples. Excellent presentation skills with very accurate communication.

Secondary Criteria

A* Outstanding

Exceeds expectations for most primary criteria Complete command of subject and other relevant areas Ideas/arguments are highly original

A+ Excellent

Exceeds expectations for some primary criteria Complete command of subject Ideas/arguments are highly original

A Good

Meets all primary criteria Command of subject but with minor gaps in knowledge areas Ideas/arguments are mostly original

A- Meets requirements of Class

Meets most but not all primary criteria Complete command of subject but with some gaps in knowledge Ideas/arguments are mostly original

1. Critically discuss the cell as a unit of health and disease.

2. Critically discuss the histogenesis of named diseases.

3. Critically discuss the cellular response to stress, injury and death.

4. Critically discuss the role of cellular and molecular pathology in identifying neoplastic conditions.

5. Critically discuss the diagnostic technologies used in cellular and molecular pathology investigations.

Type	Name	Description	Weight
	CMP Case Study 1		40.00
	CMP Case Study 2		40.00
	AV Presentation		20.00

		Hours
Seminar	Semester 1 5 x 2 hours tutorial Semester 2 5 x 2 hours tutorial	20
Private study	Directed and self-directed reading around the topic to develop in-depth knowledge and preparation for tutorial sessions and assessments.	260
Lecture	Semester 1 5 x 2 hours lecture Semester 2 5 x 2 hours lecture *Please note, for 2021/22, a blended learning style of delivery will be used.	20

• Literacy - Proficiency in reading and writing through a variety of media
• Numeracy - Proficiency in using numbers at appropriate levels of accuracy
• Computer Literacy - Proficiency in using a varied range of computer software
• Self-Management - Able to work unsupervised in an efficient, punctual and structured manner. To examine the outcomes of tasks and events, and judge levels of quality and importance
• Exploring - Able to investigate, research and consider alternatives
• Information retrieval - Able to access different and multiple sources of information
• Inter-personal - Able to question, actively listen, examine given answers and interact sensitevely with others
• Critical analysis & Problem Solving - Able to deconstruct and analyse problems or complex situations. To find solutions to problems through analyses and exploration of all possibilities using appropriate methods, rescources and creativity.
• Presentation - Able to clearly present information and explanations to an audience. Through the written or oral mode of communication accurately and concisely.
• Argument - Able to put forward, debate and justify an opinion or a course of action, with an individual or in a wider group setting
• Self-awareness & Reflectivity - Having an awareness of your own strengths, weaknesses, aims and objectives. Able to regularly review, evaluate and reflect upon the performance of yourself and others

QAA Characteristics Statement Category 2: Specialised or advanced study master's MSc degree

Specialist subject knowledge in cellular and molecular causes of disease. Specialist subject knowledge in cellular and molecular pathological diagnosis.

Resource implications for students

All resources needed to complete this module are provided. Computers can be accessed in multiple locations across the university. All teaching materials will be available on Blackboard. Completed assignments will be uploaded onto Turnitin through Blackboard. Limited number of textbooks will be available through the University library.

Talis Reading list

http://readinglists.bangor.ac.uk/modules/mse-4091.html