Module MSE-2033:
Principles of Pharmacology
Principles of Pharmacology 2024-25
MSE-2033
2024-25
North Wales Medical School
Module - Semester 1 & 2
20 credits
Module Organiser:
Dyfrig Hughes
Overview
This module will develop pre-existing knowledge gained during the first year foundations in therapeutics module by introducing and extending knowledge in the core principles of pharmacology, namely pharmacokinetics (how drugs are absorbed, distributed, metabolised and eliminated) and pharmacodynamics (the mechanisms by which drugs exert their effects).
This module will develop pre-existing knowledge gained during the first year foundations in therapeutics module and expand upon it significantly. The module will ensure coverage of the following topic areas:
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Pharmacokinetics, which include the processes of drug absorption, distribution, metabolism and excretion. Students will gain an understanding of the systemic availability of drugs, and the influence of route of administration; protein binding and tissue distribution; phase 1 and 2 drug metabolism; and renal excretion. Students will be able to perform pharmacokinetic calculations.
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Pharmacodynamics, which describes the mechanism of drug action, and includes interactions with receptors, transporters, and enzymes. Students will learn about dose-response relationships, and properties of the dose-response curve.
Assessment Strategy
2000 word essay 2 hour examination
-threshold -Category D (40-49%):Completed assessments present sufficient relevant accurate taught material to satisfy the learning outcomes of the module. Essays, answers and reports are sufficiently coherent and well presented to demonstrate threshold level 5 knowledge and understanding of module material. -good -Category B (60%-69%):Completed assessments present overall good accurate relevant taught material, integrated with some directed core text outside-reading. Essays, answers and reports are well organised and structured, contain good coherent arguments, and demonstrate good overall knowledge and understanding of all module material. -excellent -Category A (70%-100%):Completed assessments present very accurate relevant taught material, integrated with numerous directed outside core text-reading and some self-researched information sources. Essays, answers and reports present very coherent and well organised arguments that demonstrate excellent overall knowledge and understanding of all module material. Evidence of in depth critical thinking and wider reading are important for grades of A+ and above
Learning Outcomes
- Analyse the quantitative relationships between drug concentration, effects and time
- Demonstrate an understanding of pharmacodynamics and the mechanisms by which drugs exert their pharmacological activity
- Demonstrate an understanding of pharmacokinetics and the processes of drug absorption, distribution, metabolism and excretion
Assessment method
Essay
Assessment type
Crynodol
Description
Students will be required to undertake a written examination covering any aspect of this module
Weighting
50%
Assessment method
Essay
Assessment type
Crynodol
Description
Students will be required to submit an essay detailing the pharmacokinetics and pharmacodynamics of a drug
Weighting
50%