Dr John Mulley

• The Evolution of Vertebrate ParaHox Genes DPhil (Oxford University)
• Biosystematics MSc (Imperial College London, UK)
• Genetics BSc (Liverpool University)

2019

• A high-density genetic map and molecular sex-typing assay for gerbils
  
  Brekke, T, Mulley, J, Steele, K, Denver, M, Thom, A & Supriya, S 2019, 'A high-density genetic map and molecular sex-typing assay for gerbils', Mammalian Genome.
• When one phenotype is not enough: divergent evolutionary trajectories govern venom variation in a widespread rattlesnake species
  
  Zancolli, G, Calvete, JJ, Cardwell, MD, Greene, HW, Hayes, WK, Hegarty, MJ, Herrmann, H-W, Holycross, AT, Lannutti, DI, Mulley, JF, Sanz, L, Travis, ZD, Whorley, JR, Wuster, CE & Wuster, W 2019, 'When one phenotype is not enough: divergent evolutionary trajectories govern venom variation in a widespread rattlesnake species', Proceedings of the Royal Society B: Biological Sciences, vol. 286, no. 1898. https://doi.org/10.1098/rspb.2018.2735

2018

• Report of the 2017 RSPCA/UFAW Rodent and Rabbit Welfare Group meeting
  
  Hawkins, P, McBride, A, Paiba, G, Rose, R, Prescott, MJ, Mulley, J, Izzard, S, Ridley, D, Kappel, S, Melotti, L & Hubrecht, R 2018, 'Report of the 2017 RSPCA/UFAW Rodent and Rabbit Welfare Group meeting', Animal Technology and Welfare, vol. 17, no. 2, pp. 75-42.
• Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies
  
  Brekke, T, Steele, K & Mulley, J 2018, 'Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies', G3: Genes, Genomes, Genetics, vol. 8, no. 2, pp. 679-686 . https://doi.org/10.1534/g3.117.300495

2017

• Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster
  
  Hargreaves, AD, Zhou, L, Christensen, J, Marletaz, F, Liu, S, Li, F, Jansen, PG, Spiga, E, Hansen, MT, Pedersen, SVH, Biswas, S, Seriwaka, K, Fox, BA, Taylor, WR, Mulley, J, Zhang, G, Heller, RS & Holland, PWH 2017, 'Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster', Proceedings of the National Academy of Sciences of the United States of America: PNAS, vol. 114, no. 29, pp. 7677–7682. https://doi.org/10.1073/pnas.1702930114

2016

• The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
  
  Braasch, I, Gehrke, AR, Smith, JJ, Kawasaki, K, Manousaki, T, Pasquier, J, Amores, A, Desvignes, T, Batzel, P, Catchen, J, Berlin, AM, Campbell, MS, Barrell, D, Martin, KJ, Mulley, JF, Ravi, V, Lee, AP, Nakamura, T, Chalopin, D, Fan, S, Wcisel, D, Cañestro, C, Sydes, J, Beaudry, FE, Sun, Y, Hertel, J, Beam, MJ, Fasold, M, Ishiyama, M, Johnson, J, Kehr, S, Lara, M, Letaw, JH, Litman, GW, Litman, RT, Mikami, M, Ota, T, Saha, NR, Williams, L, Stadler, PF, Wang, H, Taylor, JS, Fontenot, Q, Ferrara, A, Searle, SM, Aken, B, Yandell, M, Schneider, I, Yoder, JA, Volff, J, Meyer, A, Amemiya, CT, Venkatesh, B, Holland, PW, Guiguen, Y, Bobe, J, Shubin, NH, Di Palma, F, Alföldi, J, Lindblad-Toh, K & Postlethwait, JH 2016, 'The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons', Nature Genetics. https://doi.org/10.1038/ng.3526

2015

• Assessing the utility of the Oxford Nanopore MinION for snake venom gland cDNA sequencing
  
  Hargreaves, AD & Mulley, JF 2015, 'Assessing the utility of the Oxford Nanopore MinION for snake venom gland cDNA sequencing', PeerJ, pp. e1441. https://doi.org/10.7717/peerj.1441
• A critique of the toxicoferan hypothesis
  
  Hargreaves, AD, Tucker, AS, Mulley, JF, Gopalakrishnakone, P (ed.) & Malhotra, M (ed.) 2015, A critique of the toxicoferan hypothesis. in Evolution of Venomous Animals and Their Toxins: Toxicology. Springer Netherlands, pp. 1-15. https://doi.org/10.1007/978-94-007-6727-0_4-1

2014

• Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function
  
  Mulley, JF, Hargreaves, AD, Hegarty, MJ, Heller, RS & Swain, MT 2014, 'Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function', BMC Genomics, vol. 15, no. 1074. https://doi.org/10.1186/1471-2164-15-1074
• Testing the Toxicofera: comparative reptile transcriptomics casts doubt on the single, early evolution of the reptile venom system
  
  Hargreaves, AD, Swain, MT, Logan, DW & Mulley, JF 2014, 'Testing the Toxicofera: comparative reptile transcriptomics casts doubt on the single, early evolution of the reptile venom system', Toxicon, vol. 92, pp. 140-156. https://doi.org/10.1016/j.toxicon.2014.10.004
• Genomic organisation of the seven ParaHox genes of coelacanths
  
  Mulley, JF & Holland, PW 2014, 'Genomic organisation of the seven ParaHox genes of coelacanths', Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, vol. 322, no. 6, pp. 352-358. https://doi.org/10.1002/jez.b.22513
• A plea for standardized nomenclature of snake venom toxins
  
  Hargreaves, AD & Mulley, JF 2014, 'A plea for standardized nomenclature of snake venom toxins', Toxicon, vol. 90, pp. 351-353. https://doi.org/10.1016/j.toxicon.2014.08.070
• Restriction and Recruitment—Gene Duplication and the Origin and Evolution of Snake Venom Toxins
  
  Hargreaves, AD, Swain, MT, Hegarty, MJ, Logan, DW & Mulley, JF 2014, 'Restriction and Recruitment—Gene Duplication and the Origin and Evolution of Snake Venom Toxins', Genome Biology and Evolution, vol. 6, no. 8, pp. 2088-2095. https://doi.org/10.1093/gbe/evu166

2010

• Parallel retention of Pdx2 genes in cartilaginous fish and coelcanths.
  
  Mulley, JF & Holland, PW 2010, 'Parallel retention of Pdx2 genes in cartilaginous fish and coelcanths.', Molecular Biology and Evolution, vol. 27, no. 10, pp. 2386-2391. https://doi.org/10.1093/molbev/msq121

2009

• Comparative genomics of chondrichthyan Hoxa clusters.
  
  Mulley, JF, Zhong, YF & Holland, PW 2009, 'Comparative genomics of chondrichthyan Hoxa clusters.', BMC Evolutionary Biology, vol. 9, pp. 218. https://doi.org/10.1186/1471-2148-9-218

2008

• ParaHox cluster evolution--hagfish and beyond
  
  Furlong, RF & Mulley, JF 2008, 'ParaHox cluster evolution--hagfish and beyond', Zoological Science, vol. 25, no. 10, pp. 955-9. https://doi.org/10.2108/zsj.25.955

2006

• Breakup of a homeobox cluster after genome duplication in teleosts
  
  Mulley, JF, Chiu, C & Holland, PWH 2006, 'Breakup of a homeobox cluster after genome duplication in teleosts', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 27, pp. 10369-72. https://doi.org/10.1073/pnas.0600341103

2004

• Comparative genomics
  
  Mulley, J & Holland, P 2004, 'Comparative genomics: small genome, big insights', Nature, vol. 431, no. 7011, pp. 916-7. https://doi.org/10.1038/431916a
• Trinucleotide microsatellite loci for the peppered moth (Biston betularia)
  
  Daly, D, Waltham, K, Mulley, J, Watts, PC, Rosin, A, Kemp, SJ & Saccheri, IJ 2004, 'Trinucleotide microsatellite loci for the peppered moth (Biston betularia)', Molecular Ecology Notes, vol. 4, no. 2, pp. 179-181. https://doi.org/10.1111/j.1471-8286.2004.00607.x

• Decoding dark DNA
• Differential responses of X and Y chromosome-bearing sperm to follicular fluid from the right and left ovaries
• Refining husbandry and welfare of desert rodents
• Support for attendance at UFAW conference
• Support for attendance at UFAW conference
• Mapping the gerbil genome
• Gene duplication & regulation & evolution & development of snake venom
• The role of Pdx2 in pancreas development and function
• Resources for the study of shark populations around North-West Wales