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Prof Paul Mullins

Professor in Psychology

p.mullins@bangor.ac.uk

+44 1248 383631

0000-0002-1339-6361

Prof Paul Mullins

View Prof Paul Mullins’s profile on the Bangor Research Portal

Overview

Director of the Bangor Imaging Centre in the School of Human and Behavioural Sciences, home to a research dedicated 3T whole body MRI system used for functional and structural imaging studies. 

Liaising with researchers from the College of Human Sciences on study design, data acquisition and processing and resources available to help with their research questions, my aim is to keep the Bangor Imaging Unit a world-class center for neuroimaging research in North Wales.

My personal research falls into three broad areas: development and validation of MRS techniques for the detection of neurotransmitters; the use of these techniques to measure changes associated with neurotransmission and neural activity in health and disease; and the use of magnetic resonance imaging to investigate basic neurologic and physiologic processes in health and disease. My current ongoing research however is focused on two of these areas: the study of functional neurochemical changes through the use of functional magnetic resonance spectroscopy (fMRS); and measurement of changes in cerebral physiology and blood flow.

fMRS

Based on the same principles as MRS, fMRS collects multiple MRS spectra in a dynamic series to study metabolite concentration changes during brain function. fMRS is able to measure changes in neurotransmitters over very short time scales, in seconds rather than minutes, either alone, or combined with other measures of neural activity such as EEG and BOLD.  Direct measurement of neurotransmitter and neurometabolite changes allows fundamental questions to be addressed regarding the excitatory, inhibitory and metabolic processes underlying neural activity.

Cerebral Phsyiology

Understanding the what, how, and why, of cerebral blood flow (CBF) changes, has implications for many fields of research, from clinical conditions (stroke, brain injury, hypoxia, Alzhiemers) to basic cognition (fMRI is based on blood flow changes).  Similarly, it is important to understand the physiologic drivers for change, and what other changes in physiology affect CBF.  Current work is investigating the effects of prolonged hypoxic exposure as might be experienced at altitude on CBF and cognition, the effects of healthy ageing, and possible relationships between resting levels of neurotransmitters and blood flow.

Teaching activities

I am the course director of the MSc in Neuroimaging, and lecturer for the “Introduction to Neuroimaging”, "Introduction to Neuroimaging analysis", “Advanced Techniques in Neuroimaging” and "Advanced Neuroimaging analysis" modules.  I have supervised 4 PhD students to completion, and currently have co-supervision of 4 others. I also supervise several MSc students’ neuroimaging research projects that intersect with my labs research interests in neurochemistry and cerebral physiology, having already successfully supervised 28 MSc students to completion.

Wider Scientific Involvement

Recognizing the importance of open and shared science I am actively involved in collaborative research with colleagues in the USA, Ireland, Norway and the UK. I am also a well-respected member of the international magnetic resonance spectroscopy (MRS) research community,having been on the organizing committee for several international symposia, and recently involved in developing the Minimum Reporting Standards for Magnetic Resonance Spectroscopy. 

Qualifications

  • PhD: Application of Magnetic Resonance Imaging (MRI) to animal models of cerebral ischaemia
    University of Queensland, 2002
  • Other: Biochemistry Honours
    James Cook University of Far North Queensland, Townsville, 1995
  • BSc: Chemistry and Biochemistry
    James Cook University of Far North Queensland, 1993

Teaching and Supervision

Programe Director:

Masters in Neuroimaging

Module organiser and Lecturer:

Introduction to Neuroimaging.

Introduction to Neuroimaging analysis

Advanced Neuroimaging analysis

Supervisor:

6 Masters Students projects in 2019-20

10 undergraduate disertations

PhD supervision -

First supervisor:

Matthew Rogan

Joseph Smith

Second Supervisor:

Myrto Mantazaria

Vallilath Madham Vinod Ramakrishnan

Joshua Payne - Graduated

Pauliina Sorvino - Graduated

Shelby DeMeulenaere - Graduated

Gabriella Rosetti - Graduated 

 

Postgraduate Project Opportunities

 Self-funded (inc. agency-funded) projects: Professor Mullins welcomes informal enquiries from prospective PhD students interested in projects related to functional magnetic resonance spectroscopy, imaging of cerebral physiology, and/or neuroimaging in general. Please submit a draft research proposal (1-2 pages) to p.mullins@bangor.ac.uk.

Competitive scholarship opportunities available: None at present, but I am always ready to investigate opportunities.

Publications

2022

  • PublishedChronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium
    Alzheimer's Association Global SARS-COV-2 Consortium, 22 Sep 2022, In: Alzheimer's & dementia (New York, N. Y.). 8, 1, e12348.
    Research output: Contribution to journal › Article › peer-review
  • PublishedHypoxia alters posterior cingulate cortex metabolism during a memory task: a 1H fMRS study
    Rogan, M., Friend, A., Rossetti, G. M. K., Edden, R. A. E., Mikkelsen, M., Oliver, S., Macdonald, J. & Mullins, P., 15 Oct 2022, In: Neuroimage. 260, 119397.
    Research output: Contribution to journal › Article › peer-review
  • PublishedNeurochemistry of response inhibition and interference in gambling disorder: A preliminary study of γ-aminobutyric acid (GABA+) and glutamate-glutamine (Glx)
    Weidacker, K., Johnston, S. J., Mullins, P. G., Boy, F. & Dymond, S., Aug 2022, In: CNS Spectrums. 27, 4, p. 475-485 11 p.
    Research output: Contribution to journal › Article › peer-review

2021

  • PublishedBilateral regional extracranial blood flow regulation to hypoxia and unilateral duplex ultrasound measurement error
    Friend, A., Rogan, M., Rossetti, G., Lawley, J., Mullins, P., Sandoo, A., Macdonald, J. & Oliver, S., 1 Jul 2021, In: Experimental Physiology. 106, 7, p. 1535-1548 14 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedFrequency drift in MR spectroscopy at 3T
    Hui, S. C. N., Mikkelsen, M., Zöllner, H. J., Ahluwalia, V., Alcauter, S., Baltusis, L., Barany, D. A., Barlow, L. R., Becker, R., Berman, J. I., Berrington, A., Bhattacharyya, P. K., Blicher, J. U., Bogner, W., Brown, M. S., Calhoun, V. D., Castillo, R., Cecil, K. M., Choi, Y. B., Chu, W. C. W., Clarke, W. T., Craven, A. R., Cuypers, K., Dacko, M., de la Fuente-Sandoval, C., Desmond, P., Domagalik, A., Dumont, J., Duncan, N. W., Dydak, U., Dyke, K., Edmondson, D. A., Ende, G., Ersland, L., Evans, C. J., Fermin, A. S. R., Ferretti, A., Fillmer, A., Gong, T., Greenhouse, I., Grist, J. T., Gu, M., Harris, A. D., Hat, K., Heba, S., Heckova, E., Hegarty, J. P., Heise, K-F., Jacobson, A., Jansen, J. F. A., Jenkins, C. W., Johnston, S. J., Juchem, C., Kangarlu, A., Kerr, A. B., Landheer, K., Lange, T., Lee, P., Levendovszky, S. R., Limperopoulos, C., Liu, F., Lloyd, W., Lythgoe, D. J., Machizawa, M. G., MacMillan, E. L., Maddock, R. J., Manzhurtsev, A. V., Martinez-Gudino, M. L., Miller, J. J., Mirzakhanian, H., Moreno-Ortega, M., Mullins, P. G., Near, J., Noeske, R., Nordhøy, W., Oeltzschner, G., Osorio-Duran, R., Otaduy, M. C. G., Pasaye, E. H., Peeters, R., Peltier, S. J., Pilatus, U., Polomac, N., Porges, E. C., Pradhan, S., Prisciandaro, J. J., Puts, N. A., Rae, C. D., Reyes-Madrigal, F., Roberts, T. P. L., Robertson, C. E., Rosenberg, J. T., Rotaru, D-G., O'Gorman Tuura, R. L., Saleh, M. G., Sandberg, K., Sangill, R., Schembri, K., Schrantee, A., Semenova, N. A., Singel, D., Sitnikov, R., Smith, J., Song, Y., Stark, C., Stoffers, D., Swinnen, S. P., Tain, R., Tanase, C., Tapper, S., Tegenthoff, M., Thiel, T., Thioux, M., Truong, P., van Dijk, P., Vella, N., Vidyasagar, R., Vovk, A., Wang, G., Westlye, L. T., Wilbur, T. K., Willoughby, W. R., Wilson, M., Wittsack, H-J., Woods, A. J., Wu, Y-C., Xu, J., Lopez, M. Y., Yeung, D. K. W., Zhao, Q., Zhou, X., Zupan, G., Edden, R. A. E., Nakajima, S. L. & Honda, S., 1 Nov 2021, In: Neuroimage. 241, 118430.
    Research output: Contribution to journal › Article › peer-review
  • PublishedMinimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus recommendations
    Experts' Working Group on Reporting Standards for MR Spectroscopy, 1 May 2021, In: NMR in biomedicine. 34, 5, e4484.
    Research output: Contribution to journal › Article › peer-review
  • PublishedReversal of neurovascular coupling in the default mode network: Evidence from hypoxia
    Rossetti, G., d'Avossa, G., Rogan, M., Macdonald, J., Oliver, S. & Mullins, P., Apr 2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 4, p. 805–818 14 p.
    Research output: Contribution to journal › Article › peer-review

2020

  • PublishedCircadian circuits in humans: White matter microstructure predicts daytime sleepiness
    Koller, K., Rafal, R. D. & Mullins, P. G., Jan 2020, In: Cortex. 122, p. 97-107 11 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedImpulsive decision-making and gambling severity: The influence of γ-amino-butyric acid (GABA) and glutamate-glutamine (Glx)
    Weidacker, K., Johnston, S. J., Mullins, P. G., Boy, F. & Dymond, S., Mar 2020, In: European Neuropsychopharmacology. 32, p. 36-46
    Research output: Contribution to journal › Article › peer-review

2019

  • PublishedMethodological consensus on clinical proton MRS of the brain: Review and recommendations
    Wilson, M., Andronesi, O., Barker, P. B., Bartha, R., Bizzi, A., Bolan, P. J., Brindle, K. M., Choi, I-Y., Cudalbu, C., Dydak, U., Emir, U. E., Gonzalez, R. G., Gruber, S., Gruetter, R., Gupta, R. K., Heerschap, A., Henning, A., Hetherington, H. P., Huppi, P. S., Hurd, R. E., Kantarci, K., Kauppinen, R. A., Klomp, D. W. J., Kreis, R., Kruiskamp, M. J., Leach, M. O., Lin, A. P., Luijten, P. R., Marjańska, M., Maudsley, A. A., Meyerhoff, D. J., Mountford, C. E., Mullins, P. G., Murdoch, J. B., Nelson, S. J., Noeske, R., Öz, G., Pan, J. W., Peet, A. C., Poptani, H., Posse, S., Ratai, E-M., Salibi, N., Scheenen, T. W. J., Smith, I. C. P., Soher, B. J., Tkáč, I., Vigneron, D. B. & Howe, F. A., Aug 2019, In: Magnetic Resonance in Medicine. 82, 2, p. 527-550 24 p.
    Research output: Contribution to journal › Review article › peer-review
  • PublishedRegional Striatal Cholinergic Involvement in Human Behavioral Flexibility
    Bell, T., Lindner, M., Langdon, A., Mullins, P. G. & Christakou, A., 17 Jul 2019, In: Journal of Neuroscience. 39, 29, p. 5740-5749 10 p.
    Research output: Contribution to journal › Article › peer-review

2018

  • PublishedAlleviating anxiety in patients prior to MRI: A pilot single-centre single-blinded randomised controlled trial to compare video demonstration or telephone conversation with a radiographer versus routine intervention
    Tugwell, J. R., Goulden, N. & Mullins, P., May 2018, In: Radiography. 24, 2, p. 122-129
    Research output: Contribution to journal › Article › peer-review
  • PublishedBeyond static measures: A review of functional magnetic resonance spectroscopy and its potential to investigate dynamic glutamatergic abnormalities in schizophrenia
    Jelen, L. A., King, S., Mullins, P. & Stone, J. M., 1 May 2018, In: Journal of Psychopharmacology. 32, 5, p. 497-508
    Research output: Contribution to journal › Article › peer-review
  • PublishedErrors in H-MRS estimates of brain metabolite concentrations caused by failing to take into account tissue-specific signal relaxation
    Gasparovic, C., Chen, H. & Mullins, P. G., Jun 2018, In: NMR in biomedicine. 31, 6, p. e3914
    Research output: Contribution to journal › Article › peer-review
  • PublishedFunctional neurochemical imaging of the human striatal cholinergic system during reversal learning
    Bell, T., Lindner, M., Mullins, P. G. & Christakou, A., 23 May 2018, In: European Journal of Neuroscience. 47, 10, p. 1184-1193
    Research output: Contribution to journal › Article › peer-review
  • PublishedTowards a Theory of Functional Magnetic Resonance Spectroscopy (fMRS): A Meta-analysis and discussion of using MRS to measure changes in neurotransmitters in real time
    Mullins, P., Feb 2018, In: Scandinavian Journal of Psychology. 59, p. 91-103
    Research output: Contribution to journal › Article › peer-review

2017

  • PublishedAging-related microstructural alterations along the length of the cingulum bundle
    Sibilia, F., Kehoe, E. G., Farrell, D., Kerskens, C., O'Neill, D., McNulty, J. P., Mullins, P. G. & Bokde, A., 1 Aug 2017, In: Brain connectivity. 7, 6, p. 366-372
    Research output: Contribution to journal › Article › peer-review
  • PublishedIn vivo functional neurochemistry of human cortical cholinergic function during visuospatial attention
    Lindner, M., Bell, T., Iqbal, S., Mullins, P. G. & Christakou, A., 13 Feb 2017, In: PLoS ONE. 12, 2, e0171338.
    Research output: Contribution to journal › Article › peer-review
  • PublishedUnexpected reductions in regional cerebral perfusion during prolonged hypoxia
    Lawley, J., Oliver, S., Macdonald, J. & Mullins, P., 1 Jan 2017, In: Journal of Physiology. 595, 3, p. 935-947
    Research output: Contribution to journal › Article › peer-review
  • PublishedWhat do people with dementia and their carers want to know about neuroimaging for dementia?
    Featherstone, H., Butler, M-L., Ciblis, A., Bokde, A. L., Mullins, P. G. & McNulty, J. P., May 2017, In: Dementia. 16, 4, p. 461-470
    Research output: Contribution to journal › Article › peer-review

2016

  • PublishedCurrent practice in the referral of individuals with suspected dementia for neuroimaging by General Practitioners in Ireland and Wales
    Ciblis, A. S., Butler, M. L., Quinn, C., Clare, L., Bokde, A. L., Mullins, P. G. & McNulty, J. P., 23 Mar 2016, In: PLoS ONE.
    Research output: Contribution to journal › Article › peer-review
  • PublishedThe use of neuroimaging in dementia by Irish general practitioners
    Ciblis, A. S., Butler, M-L., Bokde, A. L. W., Mullins, P. G. & McNulty, J. P., Aug 2016, In: Irish Journal of Medical Science. 185, 3, p. 597-602 6 p.
    Research output: Contribution to journal › Article › peer-review

2015

  • PublishedConnectivity between the superior colliculus and the amygdala in humans and macaque monkeys: virtual dissection with probabilistic DTI tractography
    Rafal, R. D., Koller, K., Bultitude, J. H., Mullins, P. G., Ward, R. A., Mitchell, A. S. & Bell, A. H., 1 Sep 2015, In: Journal of Neurophysiology. 114, 3, p. 1947-1962
    Research output: Contribution to journal › Article › peer-review
  • PublishedEvent-related dynamics of glutamate and BOLD effects measured using functional magnetic resonance spectroscopy (fMRS) at 3T in a repetition suppression paradigm
    Apsvalka, D., Gadie, A. M., Clemence, M. & Mullins, P. G., 10 Jun 2015, In: Neuroimage. 118, p. 292-300
    Research output: Contribution to journal › Article › peer-review
  • PublishedFornix white matter is correlated with resting-state functional connectivity of the thalamus and hippocampus in healthy aging but not in mild cognitive impairment – a preliminary study
    Kehoe, E. G., Farrell, D., Metzler-Baddeley, C., Lawlor, B. A., Kenny, R. A., Lyons, D., McNulty, J. P., Mullins, P. G., Coyle, D. & Bokde, A. L., 5 Feb 2015, In: Frontiers in Aging Neuroscience. 7, p. 1-10 10.
    Research output: Contribution to journal › Article › peer-review
  • PublishedNeuroimaging referral for dementia diagnosis: The specialist's perspective in Ireland
    Ciblis, A. S., Butler, M. L., Bokde, L. W., Mullins, P. G., O'Neill, D. & McNulty, J. P., 29 Mar 2015, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 1, p. 41-47
    Research output: Contribution to journal › Article › peer-review
  • PublishedThe Subjective Experience of Pain: An FMRI Study of Percept-Related Models and Functional Connectivity
    Wilcox, C. E., Mayer, A. R., Teshiba, T. M., Ling, J., Smith, B. W., Wilcox, G. L. & Mullins, P. G., 19 May 2015, In: Pain Medicine. 16, 11, p. 2121-2133
    Research output: Contribution to journal › Article › peer-review
  • PublishedThe neural substrates for the different modalities of movement imagery
    Jiang, D., Edwards, M. G., Mullins, P. & Callow, N., Jul 2015, In: Brain and Cognition. 97, p. 22-31
    Research output: Contribution to journal › Article › peer-review

2014

  • PublishedAccess to Neuroimaging in Dementia: A Survey of Specialists
    Ciblis, A., Butler, M-L., Bokde, A., Mullins, P., O'Neill, D. & McNulty, J., Sep 2014, In: Irish Journal of Medical Science. 183, p. S330-S330
    Research output: Contribution to journal › Meeting Abstract › peer-review
  • PublishedAdvances in MRI biomarkers for the diagnosis of Alzheimer's disease
    Kehoe, E. G., McNulty, J. P., Mullins, P. G. & Bokde, A. L. W., 1 Oct 2014, In: Biomarkers in Medicine. 8, 9, p. 1151-69 19 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedAnabolic exercise in haemodialysis patients: a randomised controlled pilot study
    Kirkman, D., Mullins, P. G., Junglee, N. A., Kumwenda, M., Jibani, M. M. & Macdonald, J. H., Sep 2014, In: Journal of Cachexia, Sarcopenia and Muscle. 5, 3, p. 199-207
    Research output: Contribution to journal › Article › peer-review
  • PublishedCurrent practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
    Mullins, P. G., McGonigle, D. J., O'Gorman, R. L., Puts, N. A. J., Vidyasagar, R., Evans, C. J., Edden, R. A. E. & Cardiff Symposium on MRS of GABA, 1 Feb 2014, In: Neuroimage. 86, p. 43-52 10 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedGlutamatergic correlates of gamma-band oscillatory activity during cognition: A concurrent ER-MRS and EEG study
    Lally, N., Mullins, P. G., Roberts, M. V., Price, D., Gruber, T. & Haenschel, C., 15 Jan 2014, In: Neuroimage. 85, Part 2, p. 823-833
    Research output: Contribution to journal › Article › peer-review
  • PublishedNormobaric hypoxia and symptoms of acute mountain sickness: Elevated brain volume and intracranial hypertension
    Lawley, J. S., Alperin, N., Bagci, A. M., Lee, S. H., Mullins, P. G., Oliver, S. J. & Macdonald, J. H., 20 May 2014, In: Annals of Neurology. 75, 6, p. 890-898
    Research output: Contribution to journal › Article › peer-review
  • PublishedPrefrontal glutamate abnormality alters fronto-striatal relationship in subjects at ultra high risk for psychosis
    Koychev, I., Winton-Brown, T., Egerton, A., Mullins, P., Kapur, S., Mathews, P., McGuire, P. & Stone, J., Nov 2014, In: Early Intervention in Psychiatry. 8, p. 60-60
    Research output: Contribution to journal › Meeting Abstract › peer-review
  • PublishedProlonged (9 h) poikilocapnic hypoxia (12% O2) augments cutaneous thermal hyperaemia in healthy humans
    Lawley, J. S., Oliver, S. J., Mullins, P. G., Macdonald, J. H. & Moore, J. P., 1 Jun 2014, In: Experimental Physiology. 99, p. 909-920
    Research output: Contribution to journal › Article › peer-review
  • PublishedThe neural correlates of beauty comparison
    Kedia, G., Mussweiler, T., Mullins, P. G. & Linden, D., May 2014, In: Social Cognitive and Affective Neuroscience. 9, 5, p. 681-688
    Research output: Contribution to journal › Article › peer-review
  • PublishedThe salience network is responsible for switching between the default mode network and the central executive network: Replication from DCM
    Goulden, N., Khusnullina, A. A., Davis, N. J., Bracewell, R. M., Bokde, A. L., McNulty, J. P. & Mullins, P. G., 1 Oct 2014, In: Neuroimage. 99, p. 180-190
    Research output: Contribution to journal › Article › peer-review

2013

  • PublishedInvestigation of whole-brain white matter identifies altered water mobility in the pathogenesis of high-altitude headache
    Lawley, J., Oliver, S. J., Mullins, P. G. & Macdonald, J. H., 1 Aug 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 8, p. 1286-1294
    Research output: Contribution to journal › Article › peer-review
  • PublishedReproducibility of 1H-MRS measurements in schizophrenic patients
    Mullins, P. G., Rowland, L., Bustillo, J., Bedrick, E. J., Lauriello, J. & Brooks, W. M., Oct 2013, In: Magnetic Resonance in Medicine. 50, 4, p. 704-707 4 p.
    Research output: Contribution to journal › Article › peer-review

2012

  • PublishedArteriovenous fistula complication following MRI
    Kirkman, D., Junglee, N. A., Mullins, P. G. & Macdonald, J. H., 27 Aug 2012, In: British Medical Journal Case Reports.
    Research output: Contribution to journal › Article › peer-review
  • PublishedOptic Nerve Sheath Diameter Is Not Related to High Altitude Headache: A Randomized Controlled Trial
    Lawley, J. S., Oliver, S. J., Mullins, P. G., Morris, D., Junglee, N. A., Jelleyman, C. & Macdonald, J. H., 1 Sep 2012, In: High Altitude Medicine and Biology. 13, 3, p. 193-199
    Research output: Contribution to journal › Article › peer-review

2011

  • PublishedGlutamate as a marker of cognitive function in Schizophrenia: a proton spectroscopic imaging study at 4 Tesla.
    Bustillo, J. R., Chen, H., Gasparovic, C., Mullins, P. G., Caprihan, A., Qualls, C., Apfeldorf, W., Lauriello, J. & Posse, S., 1 Jan 2011, In: Biological Psychiatry. 69, 1, p. 19-27
    Research output: Contribution to journal › Article › peer-review
  • PublishedPerturbation of the Glutamate–Glutamine System in Alcohol Dependence and Remission
    Thoma, R., Mullins, P. G., Ruhl, D., Monnig, M., Yeo, R. A., Caprihan, A., Bogenschutz, M., Lysne, P., Tonigan, S., Kalyanam, R. & Gasparovic, C., 9 Mar 2011, In: Neuropsychopharmacology. 36, 7, p. 1359–1365
    Research output: Contribution to journal › Article › peer-review

2010

  • Published1H-MRS at 4 Tesla in minimally treated early schizophrenia.
    Bustillo, J. R., Rowland, L. M., Mullins, P. G., Jung, R., Chen, H., Qualls, C., Hammond, R., Brooks, W. M. & Lauriello, J., 1 Jun 2010, In: Molecular Psychiatry. 15, 6, p. 629-636
    Research output: Contribution to journal › Article › peer-review

2009

  • PublishedAlteration of the Glutamine-Glutamate cycle in Chronic Alcoholism.
    Ruhl, D. A., Gasparovic, C., Mullins, P. G., Yeo, R. A. & Thoma, R. J., 20 Jun 2009.
    Research output: Contribution to conference › Paper
  • PublishedElevated cerebral blood flow and volume in systemic Lupus measured by dynamic susceptibility contrast magnetic resonance imaging.
    Gasparovic, C. M., Roldan, C. A., Sibbitt, W. L., Qualls, C. R., Mullins, P. G., Sharrar, J. M., Yamamoto, J. J. & Bockholt, H. J., 1 Sep 2009, In: Journal of Rheumatology. 37, 9, p. 1834-1843
    Research output: Contribution to journal › Article › peer-review
  • PublishedMitochondrial function in physically active elders with sarcopenia.
    Waters, D. L., Mullins, P. G., Qualls, C. R., Raj, D. S., Gasparovic, C. & Baumgartner, R. N., 1 May 2009, In: Mechanisms of Ageing and Development. 130, 5, p. 315-319
    Research output: Contribution to journal › Article › peer-review
  • PublishedQuantitative Spectroscopic Imaging with In Situ Measurements of Tissue Water T-1, T-2, and Density.
    Gasparovic, C., Neeb, H., Feis, D. L., Damaraju, E., Chen, H., Doty, M. J., South, D. M., Mullins, P. G., Bockholt, H. J. & Shah, N. J., 1 Sep 2009, In: Magnetic Resonance in Medicine. 62, 3, p. 583-590
    Research output: Contribution to journal › Article › peer-review
  • PublishedThe Role of Resilience and Purpose in Life in Habituation to Heat and Cold Pain.
    Smith, B. W., Tooley, E. M., Montague, E. Q., Robinson, A. E., Cosper, C. J. & Mullins, P. G., 1 May 2009, In: Journal of Pain. 10, 5, p. 493-500
    Research output: Contribution to journal › Article › peer-review

2008

  • PublishedComparative reliability of proton spectroscopy techniques designed to improve detection of J-coupled metabolites.
    Mullins, P. G., Chen, H., Xu, J., Caprihan, A. & Gasparovic, C., 1 Oct 2008, In: Magnetic Resonance in Medicine. 60, 4, p. 964-969
    Research output: Contribution to journal › Article › peer-review
  • PublishedHabituation and sensitization to heat and cold pain in women with fibromyalgia and healthy controls.
    Smith, B. W., Tooley, E. M., Montague, E. Q., Robinson, A. E., Cosper, C. J. & Mullins, P. G., 1 Dec 2008, In: Pain. 140, 3, p. 420-428
    Research output: Contribution to journal › Article › peer-review
  • PublishedMagnetic resonance imaging of an embalmed head.
    Mullins, P. G., Delieu, J. M., John, N., Mahon, M., Mullins, P., Derricott, H. & Lim, I. S., 1 Jan 2008.
    Research output: Contribution to conference › Paper

2007

  • PublishedProton echo-planar spectroscopic imaging of J-coupled resonances in human brain at 3 and 4 Tesla.
    Posse, S., Otazo, R., Caprihan, A., Bustillo, J., Chen, H., Henry, P. G., Marjanska, M., Gasparovic, C., Zuo, C., Magnotta, V., Mueller, B., Mullins, P. G., Renshaw, P., Ugurbil, K., Lim, K. O. & Alger, J. R., 1 Aug 2007, In: Magnetic Resonance in Medicine. 58, 2, p. 236-244
    Research output: Contribution to journal › Article › peer-review

2006

  • Published4Tesla proton-magnetic resonance spectroscopy (1H-MRS) longitudinal study of early schizophrenia: Effects on N-acetyl aspartate and glutamate
    Bustillo, J. R., Rowland, L., Chen, H., Mullins, P. & John, L., Dec 2006, In: Neuropsychopharmacology. 31, p. S178-S179
    Research output: Contribution to journal › Article › peer-review
  • PublishedUse of tissue water as a concentration reference for proton spectroscopic imaging
    Gasparovic, C., Song, T., Devier, D., Bockholt, H. J., Caprihan, A., Mullins, P. G., Posse, S., Jung, R. E. & Morrison, L. A., 1 Jun 2006, In: Magnetic Resonance in Medicine. 55, 6, p. 1219-1226
    Research output: Contribution to journal › Article › peer-review

2005

  • PublishedA novel technique to study the brain's response to pain: Proton magnetic resonance spectroscopy.
    Mullins, P. G., Rowland, L. M., Jung, R. E. & Sibbitt, W. L., 1 Jun 2005, In: Neuroimage. 26, 2, p. 642-646
    Research output: Contribution to journal › Article › peer-review
  • PublishedEffects of ketamine on anterior cingulate glutamate metabolism in healthy humans: A 4-T proton MRS study.
    Rowland, L. M., Bustillo, J. R., Mullins, P. G., Jung, R. E., Lenroot, R., Landgraf, E., Barrow, R., Yeo, R., Lauriello, J. & Brooks, W. M., 1 Feb 2005, In: American Journal of Psychiatry. 162, 2, p. 394-396
    Research output: Contribution to journal › Article › peer-review

2004

  • PublishedSmall shifts in craniotomy position in the lateral fluid percussion injury model are associated with differential lesion development
    Vink, R., Mullins, P. G., Temple, M. D., Bao, W. & Faden, A. I., 8 Jul 2004, In: Journal of Neurotrauma. 18, 8, p. 839-47 9 p.
    Research output: Contribution to journal › Article › peer-review

2003

  • PublishedClosed-head minimal traumatic brain injury produces long-term cognitive deficits in mice
    Zohar, O., Schreiber, S., Getslev, V., Schwartz, J. P., Mullins, P. G. & Pick, C. G., 10 Apr 2003, In: Neuroscience. 118, 4, p. 949-55 7 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedNeurochemistry in Chronic Schizophrenia: A 4t-Proton Magnetic Resonance Spectroscopy Study
    Mullins, P. G., Rowland, L., Mullins, P., Jung, R., Lenroot, R., Lauriello, J., Brooks, W. & Bustillo, J., 1 Jan 2003, In: Schizophrenia Research. 60, 1, p. 245
    Research output: Contribution to journal › Article › peer-review
  • PublishedNeuroprotective and nootropic actions of a novel cyclized dipeptide after controlled cortical impact injury in mice
    Mullins, P. G., Faden, A. I., Fox, G. B., Di, X., Knoblach, S. M., Cernak, I., Mullins, P., Nikolaeva, M. & Kozikowski, A. P., 1 Mar 2003, In: Journal of Cerebral Blood Flow and Metabolism. 23, 3, p. 355-363
    Research output: Contribution to journal › Article › peer-review

2001

  • PublishedIschaemic preconditioning in the rat brain: a longitudinal magnetic resonance imaging (MRI) study
    Mullins, P. G., Reid, D. G., Hockings, P. D., Hadingham, S. J., Campbell, C. A., Chalk, J. B. & Doddrell, D. M., May 2001, In: NMR in biomedicine. 14, 3, p. 204-209 6 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedPresence of DNA fragmentation and lack of neuroprotective effect in DFF45 knockout mice subjected to traumatic brain injury
    Yakovlev, A. G., Di, X., Movsesyan, V., Mullins, P. G., Wang, G., Boulares, H., Zhang, J., Xu, M. & Faden, A. I., Mar 2001, In: Biomarkers in Medicine. 7, 3, p. 205-16 12 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedSelective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma
    Faden, A. I., O'Leary, D. M., Fan, L., Bao, W., Mullins, P. G. & Movsesyan, V., Feb 2001, In: Experimental Neurology. 167, 2, p. 435-44 10 p.
    Research output: Contribution to journal › Article › peer-review
  • PublishedmGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors
    Movsesyan, V. A., O'Leary, D. M., Fan, L., Bao, W., Mullins, P. G., Knoblach, S. M. & Faden, A. I., Jan 2001, In: The Journal of pharmacology and experimental therapeutics. 296, 1, p. 41-7 7 p.
    Research output: Contribution to journal › Article › peer-review

1998

  • PublishedThe effect of sample freezing on proton magic-angle spinning NMR spectra of biological tissue
    Middleton, D. A., Bradley, D. P., Connor, S. C., Mullins, P. G. & Reid, D. G., 1 Jul 1998, In: Magnetic Resonance in Medicine. 40, 1, p. 166-9 4 p.
    Research output: Contribution to journal › Article › peer-review

1996

  • PublishedLocalized 1H NMR spectroscopy of rat spinal cord in vivo
    Zelaya, F. O., Chalk, J. B., Mullins, P., Brereton, I. M. & Doddrell, D. M., Apr 1996, In: Magnetic Resonance in Medicine. 35, 4, p. 443-8 6 p.
    Research output: Contribution to journal › Article › peer-review

1995

  • PublishedChronic alcohol exposure decreases brain intracellular free magnesium concentration in rats
    Mullins, P. G. & Vink, R., 21 Aug 1995, In: Neuroreport. 6, 12, p. 1633-6 4 p.
    Research output: Contribution to journal › Article › peer-review

Activities

2021

  • Ethics and consent for clinical trials

    A talk on the ethical considerations for clinical trials, and how consent should be obtained.

    14 Jun 2021

    Activity: Oral presentation (Speaker)
  • Validation of the MSc in Cognitive Neuroscience

    External validator for the MSc in Neuroscience and MSc in Psychology at Bournemouth University

    3 Jun 2021

    Activity: Types of External academic engagement - Membership of peer review panel or committee (Contributor)

2020

  • PHOENIX GLOBAL RESEARCH ETHICS WORKSHOP

    Speaker and attendee. Presented on the process and Structures of Research Ethics Committees

    5 Oct 2020

    Activity: Participation in conference (Speaker)
  • External Examiner for MSc in Cognitive Neuroscience

    1 Sep 2020 →

    Activity: Types of External academic engagement - Membership of peer review panel or committee (Contributor)

2019

  • Review and validation of the Masters in Psychiatric Research

    Re-validation of the MSc in Psychiatric research.

    20 Nov 2019

    Activity: Examination (Examiner)
  • Towards a Theory for Functional MRS

    Invited Talk given at the Cogniton and Brain Sciences Unit, Cambridge University

    Audience numbers = 20

    1 Apr 2019

    Activity: Invited talk (Speaker)
  • Towards a Theory for Functional MRS

    Invited talk on fMRS

    Attendees = 20

    12 Mar 2019

    Activity: Invited talk (Speaker)

2018

  • Editing School

    Editing School - a three day workshop on the sue of MEGA-PRESS for edited MRS of Neurometabolites.

    Attendees = 40

    3 Dec 2018 – 6 Dec 2018

    Activity: Participation in conference (Speaker)
  • Magnetic Resonance Spectroscopy

    Guest Lecture on the Neurosciences module "Reading the brain, imaging the mind", and the Masters in Neuroimaging.

    Attendees - 20 and 25

    13 Nov 2018

    Activity: Invited talk (Speaker)
  • International Society for Magnetic resonance in Medicine

    Invited Talk on functional Magnetic Resonance Spectroscopy in the weekend Educational Sessions.

    16 Jun 2018 – 21 Jun 2018

    Activity: Participation in conference (Speaker)
  • External Examiner for the undergraduate Neurosciences Program at Kings College London.

    1 Jun 2018 – 30 Jun 2020

    Activity: Examination (Examiner)
  • Towards a Theory for Functional Magnetic Resonance Spectroscopy

    Invited Talk on my work in functional Magnetic Resonance Spectroscopy

    Attendees = 100

    17 May 2018

    Activity: Invited talk (Speaker)

2017

  • Headway North Wales Conference

    Presentation on "Neuroimaging and Neurochemistry Research in Brain Injury"

    Estimated Attendees - 100

    1 Mar 2017

    Activity: Participation in conference (Invited speaker)

2016

  • International Society of Magnetic Resonance in Medicine Workshop on MR Spectroscopy

    Moderator of the Poster Pitch session

    125 attendees

    16 Aug 2016

    Activity: Participation in workshop, seminar, course (Chair)
  • International Society of Magnetic Resonance in Medicine Workshop on MR Spectroscopy

    Shortly after introduction of in vivo magnetic resonance imaging (MRI) also first localized in vivo magnetic resonance spectra (MRS) were acquired in the early 1980s. In vivo MRS has evolved during the last 25 years in terms of localization quality and spatial resolution, acquisition speed, artifact suppression, number of detectable metabolites and quantification precision and has profited especially from improvements in B0 shim quality over the years and the significant increase of magnetic field strength that recently became available for in vivo investigations. Today it allows for non-invasive and non-ionizing determination of tissue concentrations and metabolic turn-over rates of various metabolites and compounds in animals or humans, is applied for clinical diagnostics and has established as an important tool for physiological research. In addition to late breaking results, this workshop examines the substantial advances in MRS acquisition, processing and analysis methods that have been achieved by the MRS community during the last 10 - 15 years. The workshop will feature invited scientific presentations, proffered papers, a poster session and discussion to work toward consensus in the areas of standardization, harmonization, quality assurance and guidance on best practices in MRS methodology. Target Audience This workshop is designed for MR Physicists including Ph.D. students; Postdoctoral Fellows and faculty who develop methodology and support clinical and physiological research based on MRS; as well as Psychiatrists, Neurologists, Neuro Radiologists, and Body Radiologists, who will benefit from the comprehensive overview and consensus discussions in order to define the state-of-the art of spectroscopy. The workshop is organized by the ISMRM MR Spectroscopy Study Group. Educational Objectives Upon completion of this activity, participants should be able to: Describe current MRS(I) data acquisition methodology including sequences, pre-scans and hardware requirements; Discuss current MRS(I) data processing, reconstruction and analysis methods; Compare the pro´s and cons´s of advanced MRS and MRSI methods; Identify advanced MRS(I) methods that made it into application in clinical and basic research; Summarize minimum quality standards with regard to data acquisition, processing, analysis and reporting for physiological or clinical MRS studies; and Support the ongoing consensus discussion about state-of-the-art, unmet needs and still existing limitations.

    15 Aug 2016 – 17 Aug 2016

    Activity: Participation in workshop, seminar, course (Organiser)
  • International Society for Magnetic resonance in medicine workshop on MR spectroscopy

    ISMRM workshop on MR spectroscopy.

    Speaker in Session on reporting standards for MRS articles - 125 attendees

    14 Aug 2016 – 17 Aug 2016

    Activity: Participation in conference (Speaker)

Projects

  • KESS II East Phd with Agroceutical Products Ltd BUK2E029

    01/02/2020 – 02/08/2023 (Active)

  • fMRI Research: Choice, Special Offers, and decision making

    01/06/2013 – 19/02/2014 (Finished)

  • NeuroSKILL

    01/03/2012 – 31/07/2017 (Finished)

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