Overview
Background
Dr Aamer Sandoo is a Senior Lecturer in Cardiovascular Physiology specialising in conducting clinical research involving NHS patients with rheumatoid arthritis, chronic kidney disease, breast cancer and cardiovascular disease. Dr Sandoo is also an expert in using several non-invasive assessments of blood vessel function (e.g. Laser Doppler Imaging with drug iontophoresis, flow-mediated dilatation, pulse-wave analysis, carotid ultrasound) to examine blood vessel health in response to different lifestyle and medical interventions. Dr Sandoo has authored over 45 publications in high impact-factor journals of international standard including multi-study and multi-centre primary research papers. He has also presented at over 24 National and International Conferences.
Dr Sandoo currently supervises 3 PhD students and is happy to discuss MRes and PhD opportunities with potential candidates wishing to study under his supervision.
Hobbies and Interests
As a former amateur boxer in his youth, Dr Sandoo loves to exercise! He regularly completes 10k runs, performs resistance training and is always prepared to try new sports. Dr Sandoo's main passion is motorbikes, and he is fortunate enough to regularly ride a superbike (Suzuki GSX-R 1000) on trackdays and on some of the most technical roads in England and Wales. He has completed his RoSPA advanced rider test achieving a Gold - the highest civilian rating possible. Aamer has also trekked up several well-known mountains including Scafell Pike (978m), Mount Snowdon (1085m), Mount Smolikas, Greece (2,637m) and several other well-known hikes.
Links
Google Scholar: https://scholar.google.co.uk/citations?user=5IRCnz4AAAAJ&hl=en
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=sandoo+a
YouTube Revision Channel: https://www.youtube.com/c/PhysiologyMadeEasywithDrAamerSandoo/featured
Twitter: https://twitter.com/draamersandoo
Instagram: https://www.instagram.com/draamersandoo/?hl=en
Video Methods Article: http://www.jove.com/video/52339/a-methodological-approach-to-non-invasive-assessments-vascular
Postgraduate Project Opportunities
I am willing to supervise a PhD
Publications
2023
- Accepted/In pressHypoxia-induced endothelial dysfunction: Could targeting oxidative stress provide protection?
Rossetti, G., Oliver, S., Sandoo, A. & Macdonald, J., 15 May 2023, (Accepted/In press) In: Experimental Physiology.
Research output: Contribution to journal › Article › peer-review
2021
- PublishedBilateral regional extracranial blood flow regulation to hypoxia and unilateral duplex ultrasound measurement error
Friend, A., Rogan, M., Rossetti, G., Lawley, J., Mullins, P., Sandoo, A., Macdonald, J. & Oliver, S., 1 Jul 2021, In: Experimental Physiology. 106, 7, p. 1535-1548 14 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe deleterious effects of acute hypoxia on microvascular and large vessel endothelial function
Jones, D., Macdonald, J., Sandoo, A., Oliver, S. & Rossetti, G., 1 Aug 2021, In: Experimental Physiology. 106, 8, p. 1699-1709
Research output: Contribution to journal › Article › peer-review
2020
- PublishedPrediction of cardiovascular events in rheumatoid arthritis using risk age calculations: evaluation of concordance across risk age models
Wibetoe, G., Sexton, J., Ikdahl, E., Rollefstad, S., Kitas, G. D., van Riel, P., Gabriel, S., Kvien, T. K., Douglas, K., Sandoo, A., Arts, E. E., Wallberg-Jonsson, S., Dahlqvist, S. R., Karpouzas, G., Dessein, P. H., Tsang, L., El-Gabalawy, H., Hitchon, C. A., Pascual-Ramos, V., Contreas-Yanes, I., Sfikakis, P. P., Gonzalez-Gay, M. A., Colunga-Pedraz, I. J., Galarza-Delgado, D. A., Azpiri-Lopez, J. R., Crowson, C. S. & Semb, A. G., 23 Apr 2020, In: Arthritis Research & Therapy. 22, 1, 90.
Research output: Contribution to journal › Article › peer-review - PublishedSubclinical atherosclerosis in systemic sclerosis and rheumatoid arthritis: a comparative matched-cohort study
Dimitroulas, T., Baniotopoulos, P., Pagkopoulou, E., Soulaidopoulos, S., Nightingale, P., Sandoo, A., Karagiannis, A., Douglas, K., Sachinidis, A., Garyfallos, A. & Kitas, G., Dec 2020, In: Rheumatology international. 40, 12, p. 1997-2004
Research output: Contribution to journal › Article › peer-review
2019
- PublishedComparison of the effects of exercise and anti-TNF treatment on cardiovascular health in rheumatoid arthritis: results from two controlled trials
Veldhuijzen van Zanten, J. J. C. S., Sandoo, A., Metsios, G. S., Stavropoulos-Kalinoglou, A., Ntoumanis, N. & Kitas, G. D., Feb 2019, In: Rheumatology international. 39, 2, p. 219-225
Research output: Contribution to journal › Article › peer-review - PublishedRadial artery spasm during cardiac angiography: the impact of endothelial dysfunction and anxiety
Hussain, I., Upadhyaya, C., Pritchard, A. W. & Sandoo, A., Jun 2019, In: Journal of the Royal College of Physicians of Edinburgh. 49, 2, p. 171-174
Research output: Contribution to journal › Letter › peer-review - PublishedThe Effects of Beetroot Juice on Blood Pressure, Microvascular Function and Large-Vessel Endothelial Function: A Randomized, Double-Blind, Placebo-Controlled Pilot Study in Healthy Older Adults.
Jones, T., Dunn, E., Macdonald, J., Kubis, H-P., McMahon, N. & Sandoo, A., 2 Aug 2019, In: Nutrients. 11, 8, p. 1792
Research output: Contribution to journal › Article › peer-review - PublishedThe impact of cardiorespiratory fitness on classical cardiovascular disease risk factors in rheumatoid arthritis: a cross-sectional and longitudinal study
Cooney, J., Ahmad, Y., Moore, J., Sandoo, A. & Thom, J. M., Oct 2019, In: Rheumatology international. 39, 10, p. 1759-1766
Research output: Contribution to journal › Article › peer-review
2018
- PublishedImpact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis
Crowson, C., Rollefstad, S., Ikdahl, E., Kitas, G. D., van Riel, P. L. C. M., Gabriel, S. E., Matteson, E. L., Kvien, T. K., Doughlas, K., Sandoo, A., Arts, E., Wållberg-Jonsson, S., Innala, L., Karpouzas, G., Dessein, P., Tsang, L., El-Gabalawy, H., Hitchon, C., Pascual Ramos, V., Contreras Yáñez, I., Sfikakis, P. P., Zampeli, E., Gonzalex-Gay, M. A., Corrales, A., van der Laar, M., Vonkeman, H. E., Meek, I. & Semb, A. G., Jan 2018, In: Annals of the Rheumatic Diseases. 77, 1, p. 48-54
Research output: Contribution to journal › Article › peer-review - PublishedSitting time is negatively related to microvascular endothelium-dependent function in rheumatoid arthritis
Fenton, S. A. M., Sandoo, A., Metsios, G. S., Duda, J. L., Kitas, G. D. & Veldhuijzen van Zanten, J. J. C. S., May 2018, In: Microvascular Research. 117, p. 57-60
Research output: Contribution to journal › Article › peer-review
2017
- PublishedEndothelial injury in rheumatoid arthritis: a crosstalk between dimethylarginines and systemic inflammation
Dimitroulas, T., Hodson, J., Sandoo, A., Smith, J. & Kitas, G. D., 10 Feb 2017, In: Arthritis Research & Therapy. 19, 32.
Research output: Contribution to journal › Article › peer-review - PublishedGenetic variations in the alanine–glyoxylate aminotransferase 2 (AGXT2) gene and dimethylarginines levels in rheumatoid arthritis
Dimitroulas, T., Hodson, J., Panoulas, V. F., Sandoo, A., Smith, J. & Kitas, G. D., Jun 2017, In: Amino Acids. 49, 6, p. 1133-1141
Research output: Contribution to journal › Article › peer-review - PublishedImportant Considerations for Examining Endothelial Dysfunction in Rheumatoid Arthritis
Sandoo, A., Sep 2017, In: Mediterranean Journal of Rheumatology. 28, 3, p. 12-115
Research output: Contribution to journal › Article › peer-review - PublishedRheumatoid arthritis-specific cardiovascular risk scores are not superior to general risk scores: a validation analysis of patients from seven countries
Trans-Atlantic Cardiovascular Consortium for Rheumatoid Arthritis, Jul 2017, In: Rheumatology. 56, 7, p. 1102-1110
Research output: Contribution to journal › Article › peer-review
2016
- PublishedAssociations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis
Dimitroulas, T., Sandoo, A., Hodson, J., Smith, J., Douglas, K. M. & Kitas, G. D., 2016, In: Scandinavian Journal of Rheumatology. 45, 4, p. 267-273
Research output: Contribution to journal › Article › peer-review - PublishedIn vivo microvascular and macrovascular endothelial function is not associated with circulating dimethylarginines in patients with rheumatoid arthritis: a prospective analysis of the DRACCO cohort
Dimitroulas, T., Sandoo, A., Hodson, J., Smith, J. P. & Kitas, G. D., 2016, In: Scandinavian Journal of Clinical and Laboratory Investigation. 76, 4, p. 331-337
Research output: Contribution to journal › Article › peer-review
2015
- PublishedA Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Sandoo, A. & Kitas, G. D., 2 Jul 2015, In: Journal of Visualized Experiments. 96, p. e52339
Research output: Contribution to journal › Article › peer-review - PublishedBreast cancer therapy and cardiovascular risk: focus on trastuzumab
Sandoo, A., Kitas, G. D. & Carmichael, A. R., 7 Apr 2015, In: Vascular health and risk management. 11, p. 223-8 6 p.
Research output: Contribution to journal › Review article › peer-review - PublishedPrediction of cardiovascular risk in rheumatoid arthritis: performance of original and adapted SCORE algorithms.
Sandoo, A. A., Kitas, G., Arts, A. E., Popa, C. D., Den Broeder, A. A., Donders, R., Sandoo, A., Toms, T., Rollefstad, S., Ikdahl, E., Semb, A. G., Kitas, G. D., Van Riel, P. L. & Franssen, J., 17 Feb 2015, In: Annals of the Rheumatic Diseases.
Research output: Contribution to journal › Article › peer-review - PublishedSymmetric Dimethylarginine Is Not Associated with Cumulative Inflammatory Load or Classical Cardiovascular Risk Factors in Rheumatoid Arthritis: A 6-Year Follow-Up Study
Sandoo, A. A., Dimitroulas, T., Hodson, J., Sandoo, A., Smith, J. P., Douglas, K. M. & Kitas, G. D., 1 Jul 2015, In: Mediators of Inflammation. p. ID 796562
Research output: Contribution to journal › Article › peer-review - PublishedSymmetric dimethylarginine (SDMA) serum levels in rheumatoid arthritis: correlations with insulin resistance and disease activity scores
Sandoo, A. A., Dimitroulas, T., Hodson, J., Sandoo, A., Smith, J. & Kitas, G. D., 13 Mar 2015, In: Amino Acids. 47, 9, p. 1995-2004
Research output: Contribution to journal › Article › peer-review - PublishedThe impact of abatacept treatment on the vasculature in patients with rheumatoid arthritis
Sandoo, A. A., Sandoo, A. & Kitas, G. D., 29 Jun 2015, In: Clinical and Experimental Rheumatology. 4, p. 589
Research output: Contribution to journal › Article › peer-review
2014
- PublishedAsymmetric dimethylarginine is not associated with subendocardial viability ratio in Rheumatoid Arthritis
Sandoo, A. A., Kitas, G., Dimitroulas, T., Sandoo, A., Smith, J. P. & Kitas, G. D., 10 Jan 2014, In: International Journal of Cardiology. 172, 1, p. 285-286
Research output: Contribution to journal › Article › peer-review - PublishedCumulative inflammation associates with asymmetric dimethylarginine in rheumatoid arthritis: a 6 year follow-up study.
Sandoo, A. A., Kitas, G., Sandoo, A., Dimitroulas, T., Hodson, J., Smith, J. P., Douglas, K. M. & Kitas, G. D., 3 Sep 2014, In: Rheumatology.
Research output: Contribution to journal › Article › peer-review - PublishedEndothelial dysfunction as a determinant of trastuzumab-mediated cardiotoxicity in patients with breast cancer
Sandoo, A. A., Kitas, G., Sandoo, A., Kitas, G. D. & Carmichael, A. R., 1 Mar 2014, In: Anticancer Research. 34, 3, p. 1147-1151
Research output: Contribution to journal › Article › peer-review - PublishedRelationship between dimethylarginine dimethylaminohydrolase gene variants and asymmetric dimethylarginine in patients with rheumatoid arthritis
Sandoo, A. A., Dimitroulas, T., Sandoo, A., Hodson, J., Smith, J., Panoulas, V. F. & Kitas, G. D., 27 Aug 2014, In: Atherosclerosis. 237, 1
Research output: Contribution to journal › Article › peer-review - PublishedThe relationship between cardiovascular disease risk prediction scores and vascular function and morphology in rheumatoid arthritis
Sandoo, A. A., Kitas, G., Sandoo, A., Chanchlani, N., Hodson, J., Smith, J. P., Douglas, K. M. & Kitas, G. D., 1 Dec 2014, In: Clinical and Experimental Rheumatology. 32, 6, p. 914-921
Research output: Contribution to journal › Article › peer-review
2013
- PublishedClassical cardiovascular disease risk factors associate with vascular function and morphology in rheumatoid arthritis: a six-year prospective study
Sandoo, A., Chanchlani, N., Hodson, J., Smith, J. P., Douglas, K. M. & Kitas, G. D., 2 Dec 2013, In: Arthritis Research & Therapy. 15, 6, p. R203
Research output: Contribution to journal › Article › peer-review - PublishedIndividualised exercise improves endothelial function in patients with rheumatoid arthritis
Sandoo, A. A., Kitas, G., Metsios, G. S., Stavropoulos-Kalinoglou, A., Veldhuijzen van Zanten, J., Nightingale, P., Sandoo, A., Dimitroulas, T., Kitas, G. D. & Koutedakis, Y., 31 Jul 2013, In: Annals of Rheumatic Diseases. 73, 4, p. 748-751
Research output: Contribution to journal › Article › peer-review - PublishedPredictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance
Dimitroulas, T., Sandoo, A., Veldhuijzen van Zanten, J. J. J. C. S., Smith, J. P., Hodson, J., Metsios, G. S., Stavropoulos-Kalinoglou, A. & Kitas, G. D., 2013, In: Scandinavian Journal of Rheumatology. 42, 3, p. 176-81 6 p.
Research output: Contribution to journal › Article › peer-review - PublishedProlonged QTc interval predicts all-cause mortality in patients with rheumatoid arthritis: an association driven by high inflammatory burden
Sandoo, A. A., Kitas, G., Panoulas, V. F., Toms, T. E., Douglas, K. M., Sandoo, A., Metsios, G. S., Stavropoulos-Kalinoglou, A. & Kitas, G. D., 3 Oct 2013, In: Rheumatology. 1, p. 131-137
Research output: Contribution to journal › Article › peer-review - PublishedThe association between functional and morphological assessments of endothelial function in patients with rheumatoid arthritis: a cross-sectional study
Sandoo, A., Hodson, J., Douglas, K. M., Smith, J. P. & Kitas, G. D., 2013, In: Arthritis Research & Therapy. 15, 5, p. R107
Research output: Contribution to journal › Article › peer-review
2012
- PublishedAnti-TNFα therapy transiently improves high density lipoprotein cholesterol levels and microvascular endothelial function in patients with rheumatoid arthritis: a pilot study
Sandoo, A., van Zanten, J. J. C. S. V., Toms, T. E., Carroll, D. & Kitas, G. D., 23 Jul 2012, In: BMC musculoskeletal disorders. 13, p. 127
Research output: Contribution to journal › Article › peer-review - PublishedAsymmetric dimethylarginine as a surrogate marker of endothelial dysfunction and cardiovascular risk in patients with systemic rheumatic diseases
Dimitroulas, T., Sandoo, A. & Kitas, G. D., 26 Sep 2012, In: Irish Journal of Medical Science. 13, 10, p. 12315-35 21 p.
Research output: Contribution to journal › Review article › peer-review - PublishedClinical remission following treatment with tumour necrosis factor-alpha antagonists is not accompanied by changes in asymmetric dimethylarginine in patients with rheumatoid arthritis
Sandoo, A., Dimitroulas, T., Toms, T. E., Hodson, J., Veldhuijzen van Zanten, J. J. C. S., Smith, J. P. & Kitas, G. D., Nov 2012, In: Clinical Biochemistry. 45, 16-17, p. 1399-403 5 p.
Research output: Contribution to journal › Article › peer-review - PublishedLack of association between asymmetric dimethylarginine and in vivo microvascular and macrovascular endothelial function in patients with rheumatoid arthritis
Sandoo, A., Dimitroulas, T., Veldhuijzen van Zanten, J. J. C. S., Smith, J. P., Metsios, G. S., Nightingale, P., Stavropoulos-Kalinoglou, A. & Kitas, G. D., 14 Mar 2012, In: Clinical and Experimental Rheumatology. 30, 3, p. 388-96 9 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study
Sandoo, A., Kitas, G. D., Carroll, D. & Veldhuijzen van Zanten, J. J. C. S., 17 May 2012, In: Arthritis Research & Therapy. 14, 3, p. R117
Research output: Contribution to journal › Article › peer-review - PublishedThe role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study
Sandoo, A., Protogerou, A. D., Hodson, J., Smith, J. P., Zampeli, E., Sfikakis, P. P. & Kitas, G. D., 28 Nov 2012, In: Arthritis Research & Therapy. 14, 6, p. R258
Research output: Contribution to journal › Article › peer-review
2011
- PublishedAnti-TNFα therapy may lead to blood pressure reductions through improved endothelium-dependent microvascular function in patients with rheumatoid arthritis
Sandoo, A., Panoulas, V. F., Toms, T. E., Smith, J. P., Stavropoulos-Kalinoglou, A., Metsios, G. S., Gasparyan, A. Y., Carroll, D., Veldhuijzen van Zanten, J. J. C. S. & Kitas, G. D., Nov 2011, In: Journal of human hypertension. 25, 11, p. 699-702 4 p.
Research output: Contribution to journal › Article › peer-review - PublishedDisease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis
Metsios, G. S., Stavropoulos-Kalinoglou, A., Treharne, G. J., Nevill, A. M., Sandoo, A., Panoulas, V. F., Toms, T. E., Koutedakis, Y. & Kitas, G. D., 29 Jun 2011, In: Arthritis Research & Therapy. 13, 3, p. R108
Research output: Contribution to journal › Article › peer-review - PublishedThe association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study
Sandoo, A., Carroll, D., Metsios, G. S., Kitas, G. D. & Veldhuijzen van Zanten, J. J. C. S., 21 Jun 2011, In: Arthritis Research & Therapy. 13, 3, p. R99
Research output: Contribution to journal › Article › peer-review - PublishedVascular function and morphology in rheumatoid arthritis: a systematic review
Sandoo, A., Veldhuijzen van Zanten, J. J. C. S., Metsios, G. S., Carroll, D. & Kitas, G. D., Nov 2011, In: Rheumatology. 50, 11, p. 2125-39 15 p.
Research output: Contribution to journal › Review article › peer-review
2010
- PublishedMean platelet volume in patients with rheumatoid arthritis: the effect of anti-TNF-α therapy
Gasparyan, A. Y., Sandoo, A., Stavropoulos-Kalinoglou, A. & Kitas, G. D., Jun 2010, In: Rheumatology international. 30, 8, p. 1125-9 5 p.
Research output: Contribution to journal › Article › peer-review - PublishedRheumatoid cachexia and cardiovascular disease
Metsios, G. S., Stavropoulos-Kalinoglou, A., Panoulas, V. F., Sandoo, A., Toms, T. E., Nevill, A. M., Koutedakis, Y. & Kitas, G. D., 13 Feb 2010, In: Clinical and Experimental Rheumatology. 27, 6, p. 985-8 4 p.
Research output: Contribution to journal › Article › peer-review - PublishedThe endothelium and its role in regulating vascular tone
Sandoo, A., van Zanten, J. J. C. S. V., Metsios, G. S., Carroll, D. & Kitas, G. D., 23 Dec 2010, In: The open cardiovascular medicine journal. 4, p. 302-12 11 p.
Research output: Contribution to journal › Article › peer-review - PublishedVascular function and inflammation in rheumatoid arthritis: the role of physical activity
Metsios, G. S., Stavropoulos-Kalinoglou, A., Sandoo, A., van Zanten, J. J. C. S. V., Toms, T. E., John, H. & Kitas, G. D., 23 Feb 2010, In: The open cardiovascular medicine journal. 4, p. 89-96 8 p.
Research output: Contribution to journal › Article › peer-review
2009
- PublishedAtherosclerosis in rheumatoid arthritis versus diabetes: a comparative study
Stamatelopoulos, K. S., Kitas, G. D., Papamichael, C. M., Chryssohoou, E., Kyrkou, K., Georgiopoulos, G., Protogerou, A., Panoulas, V. F., Sandoo, A., Tentolouris, N., Mavrikakis, M. & Sfikakis, P. P., Oct 2009, In: Arteriosclerosis, thrombosis, and vascular biology. 29, 10, p. 1702-8 7 p.
Research output: Contribution to journal › Article › peer-review - PublishedShort-term effects of rituximab on flow-mediated dilatation may be mediated by intravenous glucocorticoids: comment on the article by Gonzalez-Juanatey et al
Sandoo, A., Toms, T., Zanten, J. V. V., Carroll, D. & Kitas, G., 15 Jun 2009, In: Arthritis and Rheumatism. 61, 6, p. 854-5; author reply 855-6
Research output: Contribution to journal › Article › peer-review
Projects
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The effects of trastuzmab treatment on cariotoxicity in patients with breast cancer
01/01/2019 – 31/12/2019 (Finished)
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The effects of dietary nitrate supplementation
01/02/2016 – 31/03/2023 (Finished)