Rhedir gan School of Medical and Health Sciences

20.000 Credyd neu 10.000 Credyd ECTS

Semester 2

Trefnydd: Dr Gwyndaf Roberts

Students successfully completing this second year module should develop a conceptual understanding of how the different organelles and proteins contribute to the life cycle & functions of an eukaryotic cell. Disease examples and novel scientific developments are covered.

This module takes students on a journey through the eukaryotic cell. The content is arranged in 4 blocks:

Block 1: The Cell Biology of cell signalling

Block 2: Protein Homeostasis

Block 3: The Mitochondrion

Block 4: The Cytoskeleton

trothwy

Category: D (40%-49%)

Knowledge is limited to key areas & principles with gaps. No evidence of background reading. Answers are poorly focussed with some irrelevant material and/or repetition. No original interpretation and ideas. Limited problem solving skills, poor time management. Many weaknesses in presentation and accuracy. Answers use mainly key phrases without explaining them. The mark reflects how wide the knowledge gaps are and how little explanation & context is provided.

ardderchog

Category: A (70%-100%)

Strong knowledge based on the lecture material. Evidence of background study and good explanation of the biological principles. Answers are focussed with a good structure. Arguments are presented coherently. Mostly free of errors. Some limited original interpretation. Well known links between topics are described. Good problem solving & time management skills.

Upper A (A+, A*)

Comprehensive knowledge & detailed understanding with clear evidence of background study. Highly focussed answer and well structured and supported by diagrams & tables. Very good explanation and relevant context included. Written for a reader who is not familiar with the topic. Logically presented and defended arguments. No factual errors. Original interpretation and novel links between topics are developed. Excellent problem solving & time management skills.

To obtain marks in the A+ and A* range, clear evidence of background reading has to be present. Top answers based on the lecture material return low A marks.

C- i C+

Category: C (50%-59%)

Sound knowledge of key areas & principles. The main areas are understood with some minor omissions. No evidence of background study. The answer is only based on the lecture material. Answers are focussed on the question but are limited to statements which are not followed up by explanation or context. Answer may contain some irrelevant material and weaknesses in structure. Arguments presented but lack sometimes coherence. No original interpretation & ideas. Only major links between topics are described. No evidence of problem solving & time management skills. Some weaknesses in presentation and accuracy.

da

Category: B (60%-69%)

Sound knowledge of key areas & principles. The main areas are understood with some minor omissions. Limited evidence of background study. The answer is largely based on the lecture material. Answers are focussed on the question but also with some irrelevant material and weaknesses in structure. Arguments presented but lack sometimes coherence. No original interpretation & ideas. Only major links between topics are described. Evidence of problem solving & time management skills. Some weaknesses in presentation and accuracy.

1. Demonstrate an appreciation of how the basic blueprint of a cell evolved to full-fill specialised functions. (Biosciences benchmarks: 6.4 subject knowledge & 4.2 intellectual skills)

2. Demonstrate a conceptual understanding of how the different organelles and compartments interact within a living eukaryotic cell. (Biosciences benchmarks: 6.4 subject knowledge & 4.2 intellectual skills)

3. Combine knowledge and understanding of individual cellular processes to explain normal cell function. (Biosciences benchmarks: 6.3 subject knowledge & 4.2 intellectual skills)

4. Interpret knowledge and understanding of cellular processes to explain the pathogenesis and origins of disease processes. (Biosciences benchmarks: 6.2 subject knowledge & 4.2 intellectual skills)

Math	Enw	Disgrifiad	Pwysau
TRAETHAWD	Essay: Why it was worth a Nobel Prize?	Students will select a Nobel prize winner relevant to the field of Cell Biology, from the Physiology or Medicine, or Chemistry Nobel categories. They will then research the scientific background of the winner and select a key paper that contributed to them winning the prize. Students will write an essay, in the format of a "Letter to Nature", which will summarise the background of the winner, the state of knowledge prior to the selected paper, the key points of the paper, before concluding with the subsequent impact of this work.	50.00
ARHOLIAD	Exam: Block 1 (The cell biology of cell signalling)	Students will sit an exam consisting of two sections covering all topics discussed in the Block 1 (The cell biology of cell signalling) lectures: (A) MCQ style questions; (B) short answer exam questions. This exam will be available online.	12.50
ARHOLIAD	Exam: Block 2 (Protein homeostasis)	Students will sit an exam consisting of two sections covering all topics discussed in the Block 2 (Protein homeostasis) lectures: (A) MCQ style questions ; (B) short answer exam questions. This exam will be available online.	12.50
ARHOLIAD	Exam: Block 3 & 4 (The mitochondrion & The cytoskeleton)	As part of the exam period at the end of Semester 2 students will sit an exam covering all topics discussed in Blocks 3 and 4 (The mitochondrion & The cytoskeleton) lectures. Each Block will be examined separately in two parts, and each part will consist of a Section A with MCQ style questions, and a Section B with short answer exam questions. This exam will be available online.	25.00

		Oriau
Lecture	A series of lectures exploring the main cell organelles. Please note, for 2021/22, a blended learning style of delivery may be used. Students unable to attend Bangor University campus will be able to follow all aspects of the teaching online. On-campus teaching may be integrated, subject to Covid-19 related restrictions.	40
Individual Project	Students will select a Nobel prize winner relevant to the field of Cell Biology, from the Physiology or Medicine, or Chemistry Nobel categories. They will then research the scientific background of the winner and select a key paper that contributed to them winning the prize. Students will write an essay, in the format of a "Letter to Nature", which will summarise the background of the winner, the state of knowledge prior to the selected paper, the key points of the paper, before concluding with the subsequent impact of this work.	40
Private study	Students are expected to revise the lecture material and to engage with Cell Biology text books and other relevant resources during the module. The evidence of private study in both assignments informs the final module mark. The formation of study groups is encouraged.	120

• Llythrennedd - Medrusrwydd mewn darllen ac ysgrifennu drwy amrywiaeth o gyfryngau
• Rhifedd - Medrusrwydd wrth ddefnyddio rhifau ar lefelau priodol o gywirdeb
• Defnyddio cyfrifiaduron - Medrusrwydd wrth ddefnyddio ystod o feddalwedd cyfrifiadurol
• Hunanreolaeth - Gallu gweithio mewn ffordd effeithlon, prydlon a threfnus. Gallu edrych ar ganlyniadau tasgau a digwyddiadau, a barnu lefelau o ansawdd a phwysigrwydd
• Archwilio - Gallu ymchwilio ac ystyried dewisiadau eraill
• Adalw gwybodaeth - Gallu mynd at wahanol ac amrywiol ffynonellau gwybodaeth
• Sgiliau Rhyngbersonol - Gallu gofyn cwestiynau, gwrando'n astud ar atebion a'u harchwilio
• Dadansoddi Beirniadol & Datrys Problem - Gallu dadelfennu a dadansoddi problemau neu sefyllfaoedd cymhleth. Gallu canfod atebion i broblemau drwy ddadansoddiadau ac archwilio posibiliadau
• Cyflwyniad - Gallu cyflwyno gwybodaeth ac esboniadau yn glir i gynulleidfa. Trwy gyfryngau ysgrifenedig neu ar lafar yn glir a hyderus.
• Dadl - Gallu cyflwyno, trafod a chyfiawnhau barn neu lwybr gweithredu, naill ai gydag unigolyn neu mewn grwˆp ehangach
• Hunanymwybyddiaeth & Ystyried - Bod yn ymwybodol o'ch cryfderau, gwendidau, nodau ac amcanion eich hun. Gallu adolygu ,cloriannu a myfyrio'n rheolaidd ar eich perfformiad eich hun ac eraill.

Goblygiadau o ran adnoddau ar gyfer myfyrwyr

Limited copies of the textbooks will be available through the University library, however, it is also available [online][1]. [1]: https://archive.org/details/AlbertsEssentialCellBiology4thEd./mode/2up

Rhestrau Darllen Bangor (Talis)

http://readinglists.bangor.ac.uk/modules/mse-2020.html

Rhestr ddarllen

Alberts B, Bray D, Hopkin K, Johnson A, Lewis J, Ralf M et al. Essential cell biology. New York, N.Y: Garland Science; 2014.

Rhagofynion

• MSE-1007: Foundation-Molecules and Cells
• MSE-3017: Medical Genetics

Opsiynol mewn cyrsiau:

• C511: BSc Biology with Biotechnology year 2 (BSC/BIOT)
• C512: BSc Biology with Biotechnology with International Experience year 3 (BSC/BIOTIE)
• C510: MBiol Biology with Biotechnology year 2 (MBIOL/BIOT)