Dr Emily Holmes

• PhD: Understanding medication adherence: application of health psychology & behavioural economic theories
  2017
• MSc: Health Economics and Health Policy
  University of Birmingham, 2005
• BA: Economics
  University of Liverpool, 2001

Emily’s research interests and expertise include preference elicitation, medication adherence, and pharmacoeconomic evaluation.  She is Principal Investigator of studies evaluating: treatment preferences, medicines management in prison, antimicrobial prescribing, and attitudes towards epilepsy.  She is co-investigator on a study of emergency care following seizures (Collaborate), and she supports several projects in CHEME aligned to her interests of medication adherence (SuMMiT-D), preferences for medicines administration/outcomes (CARiAD), and neurology (EN-PNS, SAFE). 

Emily graduated in Economics at the University of Liverpool and started her career at the University of Manchester, before taking her position at Bangor University.  She completed her doctoral research in behavioural economics and health psychology of medication adherence.    Emily has over 40 published papers and conference proceedings, she edits health technology assessment reports for the All Wales Therapeutics and Toxicology Centre (AWTTC), and is a member of the Epilepsy Action Scientific Awards Panel and the Bangor University Athena SWAN task group.

PhD Supervision:

Nafees Din.  Androgens - CHOice of Intermittent vs Continual– Prostate Cancer (A CHOICe-PC), funded by Tenovus Cancer Care.   PhD Health Sciences, Bangor University.

Short Course Teaching:

Pharmacoeconomics short course, Bangor University. 

Online Course Contributor :

European Society for Patient Adherence, Compliance and Persistence (ESPACOMP) educational course.

Principal Investigator:

Patient centred benefit-risk assessment of treatment for colorectal liver metastases in North West England and North Wales (NWCR).

Modelling the health economic outcomes of ‘medicines management of sedating medications’ at HMP Berwyn. A feasibility study (BCUHB).

Developing a protocol and conducting an appropriately powered random-stratified sample of the UK population, to measure changing public attitudes to epilepsy and people with epilepsy (Epilepsy Action).

Cost effectiveness analysis of the use of C reactive protein point of care tests in primary care; a model based on the North Wales pilot project (BCUHB).

Co-investigator:

Developing patient-centred, feasible alternative care for emergency department users with epilepsy. A model for service design (NIHR).

Appointed Research Fellow for Health Economics:

A randomised patient-assessor blinded controlled trial of External non-invasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS).

A follow-on study to develop and pilot ‘Seizure first Aid training For Epilepsy’ (SAFE) for people with epilepsy who attend emergency departments, and their family and friends.

Supporting people with type 2 diabetes in effective use of their medicine through a system comprising mobile health technology integrate with clinical care (SUMMiT-D).

CARer-ADministration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARiAD).

2019

• CyhoeddwydSupporting people with type 2 diabetes in effective use of their medicine through mobile health technology integrated with clinical care (SuMMiT-D Feasibility): a randomised feasibility trial protocol
  Farmer, A. J., Allen, J., Bartlett, K., Bower, P., Chi, Y., French, D. P., Gudgin, B., Holmes, E., Horne, R., Hughes, D., Kenning, C., Locock, L., McSharry, J., Miles, L., Newhouse, N., Rea, R., Riga, J., Tarassenko, L., Velardo, C., Williams, N., Williams, V. & Yu, L-M., 29 Rhag 2019, Yn : BMJ Open. 2019, 9, e033504.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydDeveloping patient-centred, feasible alternative care for adult emergency department users with epilepsy: Protocol for the mixed-methods observational ‘Collaborate’ project.
  Noble, A. J., Mathieson, A., Ridsdale, L., Holmes, E., Morgan, M., McKinlay, A., Dickson, J., Jackson, M., Hughes, D., Goodacre, S. & Marson, A. G., 2 Tach 2019, Yn : BMJ Open. 9, 11, e031696.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydChallenges for economic evaluation of strategies to contain antimicrobial resistance
  Holmes, E. & Hughes, D., 27 Medi 2019, Yn : Antibiotics. 8, 4, 8 t., 166.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Sylw/Dadl
• CyhoeddwydWhat really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK
  Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Meh 2019, Yn : Epilepsy and Behavior. 95, t. 181-191
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydPatient-focused drug development methods for benefit-risk assessments: A case study using discrete choice experiment for antiepileptic drugs
  Holmes, E. A. F., Plumpton, C., Baker, G. A., Jacoby, A., Ring, A., Williamson, P., Marson, A. & Hughes, D. A., Maw 2019, Yn : Clinical Pharmacology and Therapeutics. 105, 3, t. 672-683
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydCARer-ADministration of as-needed subcutaneous medication for breakthrough symptoms in homebased dying patients (CARiAD): study protocol for a UK-based open randomised pilot trial
  Poolman, M., Roberts, J., Byrne, A., Perkins, P., Hoare, Z., Nelson, A., Hiscock, J., Hughes, D., Foster, B., O'Connor, J., Reymond, L., Healy, S., Roberts, R., Wee, B., Lewis, P., Johnstone, R., Roberts, S., Holmes, E., Wright, S., Hendry, A. & Wilkinson, C., 7 Chwef 2019, Yn : Trials. 20, 1, 16 t., 105.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydAttitudes towards epilepsy in the UK population: Results from a 2018 national survey
  Holmes, E., Bourke, S. & Plumpton, C., Chwef 2019, Yn : Seizure: European Journal of Epilepsy. 65, t. 12-19
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2018

• E-gyhoeddi cyn argraffuPeople with dementia and caregiver preferences for digital life story work service interventions: A discrete choice experiment and digital survey
  O' Philbin, L., Woods, R. & Holmes, E., 27 Rhag 2018, Yn : Aging and Mental Health.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydCost-Effectiveness Analysis of the Use of Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing in Primary Care
  Holmes, E., Harris, S. D., Hughes, A., Craine, N. & Hughes, D., 7 Rhag 2018, Yn : Antibiotics. 7, 4, 19 t., 106.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2017

• CyhoeddwydPatient preferences for outcomes in clinical trials: implications for medicines optimization
  Holmes, E., Marson, A. G. & Hughes, D., 8 Mai 2017, Yn : Trials. 18 (Suppl 1), O18, t. 192 1 t.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Crynodeb Cyfarfod

2016

• CyhoeddwydA randomised, patient-assessor blinded, sham-controlled trial of external noninvasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial): study protocol for a randomised controlled trial
  Johnson, S., Goebel, A., Richey, R., Holmes, E. & Hughes, D., 6 Rhag 2016, Yn : Trials. 17, 574.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydWhat influences persistence with medicines? A multinational discrete choice experiment of 2549 patients
  Holmes, E. A., Morrison, V. L. & Hughes, D., Awst 2016, Yn : British Journal of Clinical Pharmacology. 82, 2, t. 522-531
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydConducting Economic Evaluations Alongside Randomised Trials: Current Methodological Issues and Novel Approaches
  Hughes, D., Charles, J. M., Dawoud, D. M., Edwards, R. T., Holmes, E. A., Jones, C. L., Parham, P., Plumpton, C., Ridyard, C. O., Lloyd-Williams, H., Wood, E. M. & Yeo, S., Mai 2016, Yn : Pharmacoeconomics. 34, 5, t. 447-461
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2015

• CyhoeddwydPharmacogenetic testing prior to carbamazepine treatment of epilepsy: 1 patients’ and physicians’ preferences for testing and service delivery
  Powell, G., Holmes, E. A., Plumpton, C. O., Ring, A., Baker, G. A., Jacoby, A., Pirmohamed, M., Marson, A. G. & Hughes, D. A., 3 Gorff 2015, Yn : British Journal of Clinical Pharmacology.
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydAdherence of patients to long-term medication: a cross-sectional study of antihypertensive regimens in Austria
  Lotsch, F., Auer-Hackenberg, L., Groger, M., Rehman, K., Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., de Geest, S., Dobbels, F., Vrijens, B., Kardas, P., Hughes, D. & Ramharter, M., Mai 2015, Yn : Wiener klinische Wochenschrift. 127, 9-10, t. 379-384
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydPredictors of Self-Reported Adherence to Antihypertensive Medicines: A Multinational, Cross-Sectional Survey
  Morrison, V. L., Holmes, E. A., Parveen, S., Plumpton, C. O., Clyne, W., De Geest, S., Dobbels, F., Vrijens, B., Kardas, P. & Hughes, D., Maw 2015, Yn : Value in Health. 18, 2, t. 206-216
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2014

• CyhoeddwydPredicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research
  Holmes, E. A., Morrison, V. L. & Hughes, D., 8 Rhag 2014, Yn : Value in Health. 17, 8, t. 863-876
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydInvestigating preferences for support with life after stroke: a discreet choice experiment
  Holmes, E. A., Plumpton, C. O., Roberts, G. W., Burton, C. R., Farghrer, E., Plumpton, C., Roberts, G., Owen, H. & Roberts, E., 8 Chwef 2014, Yn : BMC Health Services Research. 14, 63, t. 1-13
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2013

• CyhoeddwydNew advice on switching antiepileptic drugs might be a false economy
  Holmes, E. A., Plumpton, C. O., Hughes, D., Holmes, E., Plumpton, C., Duerden, M., Marson, T. & Hughes, D. A., 16 Rhag 2013, Yn : British Medical Journal. 347
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydIdentification and Assessment of Adherence-Enhancing Interventions in Studies Assessing Medication Adherence Through Electronically Compiled Drug Dosing Histories: A Systematic Literature Review and Meta-Analysis
  Hughes, D., Holmes, E. A., Demonceau, J., Ruppar, T., Kristano, P., Hughes, A. D., Fargher, E., Przemyslaw, K., De Geest, S., Dobbels, F., Lewek, P., Urquhart, J. & Vrijens, B., 1 Mai 2013, Yn : Drugs. 73, 6, t. 545-562
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2012

• CyhoeddwydPreferences of people with diabetes for diabetic retinopathy screening: a discrete choice experiment
  Holmes, E. A., Yeo, S. T., Edwards, R. T., Fargher, E. A., Luzio, S. D., Thomas, R. L. & Owens, D. R., 1 Gorff 2012, Yn : Diabetic Medicine. 29, 7, t. 869-877
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydA new taxonomy for describing and defining adherence to medications
  Holmes, E. A., Hughes, D., Morrison, V. L., Vrijens, B., De Geest, S., Hughes, D. A., Prezemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K. & Urquhart, J., 1 Mai 2012, Yn : British Journal of Clinical Pharmocology. 73, 5, t. 691-705
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2011

• CyhoeddwydA Pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: the TARGET study.
  Newman, W., Payne, K., Tricker, K., Roberts, S., Fargher, E., Pushpakom, S., Alder, JE., Sidgwick, GP., Payne, D., Elliott, R. A., Heise, M., Elles, R., Ramsden, SC., Andrews, J., Houston, B., Qasim, F., Shaffer, J., Griffiths, CE., Ray, DW., Bruce, I. & Ollier, WE., 21 Meh 2011, Yn : Pharmacogenomics. 12, 6, t. 815-826
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydInvolving colleagues can be challenging
  Fargher, E. & Hughes, D., 2 Ebr 2011, Yn : Pharmaceutical Journal. 286, t. 404
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr
• CyhoeddwydValuing pharmacogenetic testing services: A comparison of patients' and health care professionals' preferences
  Holmes, E. A., Payne, K., Fargher, E. A., Roberts, S., Tricker, K., Elliott, R. A., Ratcliffe, J. & Newman, W., 1 Ion 2011, Yn : Value in Health. 14, 1, t. 121-134
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2010

• CyhoeddwydWomen's experience of commercial weight-loss programmes
  Holmes, E. A., Wickett, H. & Fargher, E. A., 1 Hyd 2010, Yn : Practice Nursing. 21, 10, t. 252-259
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2007

• CyhoeddwydIs shared care with annual hospital review better value for money than predominantly hospital-based care in patients with established stable rheumatoid arthritis?
  Holmes, E. A., Davies, L. M., Fargher, E. A., Tricker, K., Dawes, P., Scott, D. L. & Symmons, D., 1 Mai 2007, Yn : Annals of the Rheumatic Diseases. 66, 5, t. 658-663
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydTPMT testing in rheumatology: any better than routine monitoring?
  Holmes, E. A., Payne, K., Newman, W., Fargher, E. A., Tricker, K., Bruce, I. N. & Ollier, W. E., 1 Mai 2007, Yn : Rheumatology. 46, 5, t. 727-729
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl
• CyhoeddwydCurrent use of pharmacogenetic testing: a national survey of thiopurine methyltransferase testing prior to azathioprine prescription.
  Holmes, E. A., Fargher, E. A., Tricker, K., Newman, W., Elliott, R., Roberts, S. A., Shaffer, J. L., Bruce, I. & Payne, K., 1 Ebr 2007, Yn : Journal of Clinical Pharmacy and Therapeutics. 32, 2, t. 187-195
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2006

• CyhoeddwydPatients' and healthcare professionals' views on pharmacogenetic testing and its future delivery in the NHS.
  Holmes, E. A., Fargher, E. A., Eddy, C., Newman, W., Qasim, F., Tricker, K., Elliott, R. A. & Payne, K., 1 Medi 2006, Yn : Pharmacogenomics. 8, 11, t. 1511-1519
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl

2005

• CyhoeddwydResearch Governance: What is reasonable protection?
  Payne, K., Fargher, E., Tricker, K., Newman, W., Qasim, F., Poulton, K., Andrews, J., Houston, JB., Elliott, RA., Elles, R., Ray, DW., Shaffer, J., Griffiths, C., Bruce, I., Roberts, S. A. & Ollier, WE., 2005, Yn : BMJ. 330, t. 847
  Allbwn ymchwil: Cyfraniad at gyfnodolyn › Llythyr

• Patient centred benefit-risk assessment of treatment for colorectal liver metastases in North West England and North Wales

  01/06/2019 – 31/12/2020 (Wrthi'n gweithredu)

• Modelling the health economic outcomes of ‘medicines management of sedating medications’ at HMP Berwyn. A feasibility study

  01/09/2018 – 15/02/2020 (Wedi gorffen)

• Developing a protocol and conducting a sample of the UK population, to measure changing public attitudes to epilepsy and people with epilepsy

  01/03/2018 – 12/11/2018 (Wedi gorffen)

  Description

  Bangor University is carrying out a survey of public attitudes to epilepsy and people with epilepsy in the UK.

  This survey will measure the UK public attitude towards epilepsy and people with epilepsy in 2018. They will use a method that can be repeated at future time points, in order to track changing public attitudes over time.

  The results from this project will assist Epilepsy Action in planning future work to improve awareness and understanding of epilepsy.

  Cysylltau:

  • https://www.epilepsy.org.uk/research/publicattitudestoepilepsy

• Cost-effectiveness analysis of the use of C reactive protein point of care tests in primary care

  22/03/2017 – 08/11/2017 (Wedi gorffen)

Member of Bangor University Athena SWAN Task Group

Member of Epilepsy Action Scientific Awards Panel

NIHR and HCRW Reviewer

Epilepsy Action Local Services Volunteer