Dr Shelagh Malham

• Immunobiology of the Octopus Eledone cirrhosa PhD
• Joint Hons. Marine Biology and Zoology BSc

2017

• Climate and land-use change impact on faecal indicator bacteria in a temperate maritime catchment (the River Conwy, Wales)
  
  Bussi, G, Whitehead, P, Thomas, A, Masante, D, Jones, L, Cosby, J, Emmett, B, Malham, S, Prudhomme, C & Prosser, H 2017, 'Climate and land-use change impact on faecal indicator bacteria in a temperate maritime catchment (the River Conwy, Wales)' Journal of Hydrology, vol. 553, pp. 248-261. DOI: 10.1016/j.jhydrol.2017.08.011
• Physicochemical Factors Influence the Abundance and Culturability of Human Enteric Pathogens and Fecal Indicator Organisms in Estuarine Water and Sediment
  
  Hassard, F, Andrews, A, Jones, DL, Parsons, L, Jones, V, Cox, BA, Daldorph, P, Brett, H, McDonald, J & Malham, S 2017, 'Physicochemical Factors Influence the Abundance and Culturability of Human Enteric Pathogens and Fecal Indicator Organisms in Estuarine Water and Sediment' Frontiers in Microbiology, vol. 8, 1996. DOI: 10.3389/fmicb.2017.01996
• Evaluation of Two Triplex One-Step qRT-PCR Assays for the Quantification of Human Enteric Viruses in Environmental Samples
  
  Farkas, K, Peters, DE, McDonald, J, de Rougemont, A, Malham, S & Jones, D 2017, 'Evaluation of Two Triplex One-Step qRT-PCR Assays for the Quantification of Human Enteric Viruses in Environmental Samples' Food and Environmental Virology, vol. 9, no. 3, pp. 342-349. DOI: 10.1007/s12560-017-9293-5
• Critical Review on the Public Health Impact of Norovirus Contamination in Shellfish and the Environment
  
  Hassard, F, Sharp, J, Taft, H, Le Vay, L, Harris, J, McDonald, J, Tuson, K, Wilson, J, Jones, D & Malham, S 2017, 'Critical Review on the Public Health Impact of Norovirus Contamination in Shellfish and the Environment: A UK Perspective' Food and Environmental Virology, vol. 9, no. 2, pp. 123-141. DOI: 10.1007/s12560-017-9279-3
• Evaluation of Molecular Methods for the Detection and Quantification of Pathogen-Derived Nucleic Acids in Sediment
  
  Farkas, K, Hassard, F, McDonald, J, Malham, S & Jones, D 2017, 'Evaluation of Molecular Methods for the Detection and Quantification of Pathogen-Derived Nucleic Acids in Sediment' Frontiers in Microbiology, vol. 6, 53, pp. 1-12. DOI: 10.3389/fmicb.2017.00053

2016

• Decay rates of faecal indicator bacteria from sewage and ovine faeces in brackish and freshwater microcosms with contrasting suspended particulate matter concentrations
  
  Perkins, TL, Perrow, KA, Rajko-Nenow, P, Jago, CF, Jones, DL, Malham, SK & McDonald, JE 2016, 'Decay rates of faecal indicator bacteria from sewage and ovine faeces in brackish and freshwater microcosms with contrasting suspended particulate matter concentrations' Science of the Total Environment, vol. 572, pp. 1645-1652. DOI: 10.1016/j.scitotenv.2016.03.076
• Spatial patterns and environmental constraints on ecosystem services at a catchment scale
  
  Emmett, B, Cooper, D, Smart, S, Jackson, B, Thomas, A, Cosby, B, Evans, C, Glanville, H, McDonald, J, Malham, S, Marshall, M, Jarvis, S, Rajko-Nenow, P, Webb, GP, Ward, S, Rowe, E, Jones, L, Vanbergen, EJ, Keith, A, Carter, H, Pereira, MG, Hughes, S, Lebron, I, Wade, A & Jones, D 2016, 'Spatial patterns and environmental constraints on ecosystem services at a catchment scale' Science of the Total Environment, vol. 572, pp. 1586-1600. DOI: 10.1016/j.scitotenv.2016.04.004
• Use of Mytilus edulis biosentinels to investigate spatial patterns of norovirus and faecal indicator organism contamination around coastal sewage discharges
  
  Winterbourn, J, Clements, K, Lowther, JA, Malham, S, McDonald, J & Jones, D 2016, 'Use of Mytilus edulis biosentinels to investigate spatial patterns of norovirus and faecal indicator organism contamination around coastal sewage discharges' Water Research, vol. 105, no. November, pp. 241-250. DOI: 10.1016/j.watres.2016.09.002
• Abundance and Distribution of Enteric Bacteria and Viruses in Coastal and Estuarine Sediments—a Review
  
  Hassard, F, Gwyther, CL, Farkas, K, Andrews, A, Jones, V, Cox, B, Brett, H, Jones, D, McDonald, J & Malham, S 2016, 'Abundance and Distribution of Enteric Bacteria and Viruses in Coastal and Estuarine Sediments—a Review' Frontiers in Microbiology. DOI: 10.3389/fmicb.2016.01692

2015

• Impact of climate change on UK estuaries: A review of past trends and potential projections
  
  Robins, PE, Skov, MW, Lewis, MJ, Gimenez, L, Davies, AG, Malham, SK, Neill, SP, McDonald, JE, Whitton, TA, Jackson, SE & Jago, CF 2015, 'Impact of climate change on UK estuaries: A review of past trends and potential projections' Estuarine, Coastal and Shelf Science, vol. 169, pp. 119-135. DOI: 10.1016/j.ecss.2015.12.016
• Validation of the flooding dose technique to determine fractional rates of protein synthesis in a model bivalve species, the blue mussel (Mytilus edulis L.)
  
  McCarthy, ID, Nicholls, R, Malham, SK & Whiteley, NM 2015, 'Validation of the flooding dose technique to determine fractional rates of protein synthesis in a model bivalve species, the blue mussel (Mytilus edulis L.)' Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology, vol. 191, pp. 166-173. DOI: 10.1016/j.cbpa.2015.10.019

2014

• Sediment Composition Influences Spatial Variation in the Abundance of Human Pathogen Indicator Bacteria within an Estuarine Environment
  
  Perkins, TL, Clements, K, Baas, JH, Jago, CF, Jones, DL, Malham, SK & McDonald, JE 2014, 'Sediment Composition Influences Spatial Variation in the Abundance of Human Pathogen Indicator Bacteria within an Estuarine Environment' PLoS ONE, vol. 9, no. 11. DOI: 10.1371/journal.pone.0112951
• Spatial and temporal heterogeneity of bacteria across an intertidal shellfish bed: Implications for regulatory monitoring of faecal indicator organisms
  
  Malham, S, Clements, K, Quilliam, RS, Jones, DL, Wilson, J & Malham, SK 2014, 'Spatial and temporal heterogeneity of bacteria across an intertidal shellfish bed: Implications for regulatory monitoring of faecal indicator organisms' Science of the Total Environment, vol. 506, pp. 1-9. DOI: 10.1016/j.scitotenv.2014.10.100
• Future variability of solute transport in a macrotidal estuary
  
  Robins, PE, Lewis, MJ, Simpson, JH, Howlett, ER & Malham, SK 2014, 'Future variability of solute transport in a macrotidal estuary' Estuarine, Coastal and Shelf Science, vol. 151, pp. 88-99. DOI: 10.1016/j.ecss.2014.09.019
• Effectiveness of cooking to reduce Norovirus and infectious F-specific RNA bacteriophage concentrations in Mytilus edulis
  
  Flannery, J, Rajko-Nenow, P, Winterbourn, JB, Malham, SK & Jones, DL 2014, 'Effectiveness of cooking to reduce Norovirus and infectious F-specific RNA bacteriophage concentrations in Mytilus edulis' Journal of Applied Microbiology, vol. 117, no. 2, pp. 564-571. DOI: 10.1111/jam.12534
• The interaction of human microbial pathogens, particulate material and nutrients in estuarine environments and their impacts on recreational and shellfish waters
  
  Malham, SK, Rajko-Nenow, P, Howlett, E, Tuson, KE, Perkins, TL, Pallett, DW, Wang, H, Jago, CF, Jones, DL & McDonald, JE 2014, 'The interaction of human microbial pathogens, particulate material and nutrients in estuarine environments and their impacts on recreational and shellfish waters' Environmental Science: Processes and Impacts, vol. 16, pp. 2145-2155. DOI: 10.1039/C4EM00031E
• Future oceanic warming and acidification alter immune response and disease status in a commercial shellfish species, Mytilus edulis L.
  
  Mackenzie, C, Lynch, SA, Culloty, SC & Malham, SK 2014, 'Future oceanic warming and acidification alter immune response and disease status in a commercial shellfish species, Mytilus edulis L.' PLoS ONE, vol. 9, no. 6. DOI: 10.1371/journal.pone.0099712
• The potential impact of climate change on the infectious diseases of commercially important shellfish populations in the Irish Sea—a review
  
  Robins, PE, Malham, S, Rowley, AF, Cross, ME, Culloty, SC, Lynch, SA, Mackenzie, CL, Morgan, E, O'Riordan, RM, Robbins, PE, Smith, AL, Thrupp, TJ, Vogan, CL, Wootton, EC & Malham, SK 2014, 'The potential impact of climate change on the infectious diseases of commercially important shellfish populations in the Irish Sea—a review' ICES Journal of Marine Science, vol. 71, no. 4, pp. 741-759. DOI: 10.1093/icesjms/fst234
• The health status of mussels, Mytilus spp., in Ireland and Wales with the molecular identification of a previously undescribed haplosporidian
  
  Lynch, SA, Morgan, E, Carlsson, J, Mackenzie, C, Wooton, EC, Malham, SK & Culloty, SC 2014, 'The health status of mussels, Mytilus spp., in Ireland and Wales with the molecular identification of a previously undescribed haplosporidian' Journal of Invertebrate Pathology, vol. 118, pp. 59-65. DOI: 10.1016/j.jip.2014.02.012
• Ocean Warming, More than Acidification, Reduces Shell Strength in a Commercial Shellfish Species during Food Limitation
  
  Mackenzie, CL, Ormondroyd, GA, Curling, SF, Ball, RJ, Whiteley, NM & Malham, SK 2014, 'Ocean Warming, More than Acidification, Reduces Shell Strength in a Commercial Shellfish Species during Food Limitation' PLoS ONE, vol. 9, no. 1, pp. e86764. DOI: 10.1371/journal.pone.0086764

2013

• Future socio-economic and environmental sustainability of the Irish Sea requires a multi-disciplinary approach with industry and research collaboration, and cross-border partnership
  
  Mackenzie, CL, Bell, MC, Birchenough, SN, Culloty, SC, Sanderson, WG, Whiteley, NM & Malham, SK 2013, 'Future socio-economic and environmental sustainability of the Irish Sea requires a multi-disciplinary approach with industry and research collaboration, and cross-border partnership' Ocean and Coastal Management, vol. 85, no. Part A, pp. 1-6. DOI: 10.1016/j.ocecoaman.2013.08.012
• Epizoic Barnacles Act as Pathogen Reservoirs on Shellfish Beds
  
  Clements, K, Gimenez Noya, L, Jones, D, Wilson, J & Malham, SK 2013, 'Epizoic Barnacles Act as Pathogen Reservoirs on Shellfish Beds' Journal of Shellfish Research, vol. 32, no. 2, pp. 533-538. DOI: 10.2983/035.032.0233
• Review of climate change impacts on marine aquaculture in the UK and Ireland
  
  Callaway, R, Shinn, AP, Grenfell, SE, Bron, JE, Burnell, G, Cook, EJ, Crumlish, M, Culloty, S, Davidson, K, Ellis, RP, Flynn, KJ, Fox, C, Green, DM, Hays, GC, Hughes, A, Jhonston, E, Lowe, CD, Lupatsch, I, Malham, S, Mendzil, AF, Nickell, T, Pickerell, T, Rowley, AF, Stanley, MS, Tocher, DR, Turnbull, JF, Webb, G, Wootton, E & Shields, R 2013, 'Review of climate change impacts on marine aquaculture in the UK and Ireland' Aquatic Conservation: Marine and Freshwater Ecosystems, vol. 22, no. 3, pp. 389-421. DOI: 10.1002/aqc.2247
• Effects of climate change on biomineralization in a commercial shellfish species, Mytilus edulis L.
  
  Mackenzie, CL, Ormondroyd, GA, Curling, SF, Ball, RJ, Whiteley, NM & Malham, SK 2013, 'Effects of climate change on biomineralization in a commercial shellfish species, Mytilus edulis L.' Paper presented at The Future of the Irish Sea: Strategies for Environmental and Economic Sustainability, 3/01/01, .
• Physical and biological controls on larval dispersal and connectivity in a highly energetic shelf sea
  
  Robins, PE, Neill, SP, Gimenez, L, Jenkins, SR & Malham, SK 2013, 'Physical and biological controls on larval dispersal and connectivity in a highly energetic shelf sea' Limnology and Oceanography, vol. 58, no. 2, pp. 505-524. DOI: 10.4319/lo.2013.58.2.0505

2012

• Modelled larval dispersal and measured gene flow: seascape genetics of the common cockle Cerastoderma edule in the southern Irish Sea
  
  Coscia, I, Robins, PE, Porter, JS, Malham, SK & Ironside, JE 2012, 'Modelled larval dispersal and measured gene flow: seascape genetics of the common cockle Cerastoderma edule in the southern Irish Sea' Conservation Genetics. DOI: 10.1007/s10592-012-0404-4

2011

• Spatial variation of waterborne Escherichia coli - implications for routine water quality monitoring
  
  Quilliam, RS, Clements, K, Duce, CE, Cottrill, SB, Malham, SK & Jones, DL 2011, 'Spatial variation of waterborne Escherichia coli - implications for routine water quality monitoring' Journal of Water and Health, vol. 9, no. 4, pp. 734-737. DOI: 10.2166/wh.2011.057
• Unearthing human pathogens at the agricultural–environment interface: A review of current methods for the detection of Escherichia coli O157 in freshwater ecosystems
  
  Quilliam, RS, Williams, AP, Avery, LM, Malham, S & Jones, DL 2011, 'Unearthing human pathogens at the agricultural–environment interface: A review of current methods for the detection of Escherichia coli O157 in freshwater ecosystems' Agriculture, Ecosystems and Environment, vol. 140, no. 3-4, pp. 354-360. DOI: 10.1016/j.agee.2011.01.019

2010

• Summer mortality of the Pacific oyster, Crassostrea gigas, in the Irish Sea: the influence of growth, biochemistry and gametogenesis.
  
  Cotter, E, Malham, S, O'Keefe, S, Lynch, SA, Latchford, JW, King, JW, Beaumont, AR & Culloty, SC 2010, 'Summer mortality of the Pacific oyster, Crassostrea gigas, in the Irish Sea: the influence of growth, biochemistry and gametogenesis.' Aquaculture, vol. 303, no. 1-4, pp. 8-21. DOI: 10.1016/j.aquaculture.2010.02.030

2009

• Summer mortality of the Pacific oyster, Crassostrea gigas, in the Irish Sea: The influence of temperature and nutrients on health and survival.
  
  Malham, S, Cotter, E, O'Keeffe, S, Lynch, S, Culloty, SC, King, JW, Latchford, JW & Beaumont, A 2009, 'Summer mortality of the Pacific oyster, Crassostrea gigas, in the Irish Sea: The influence of temperature and nutrients on health and survival.' Aquaculture, vol. 287, no. 1-2, pp. 128-138. DOI: 10.1016/j.aquaculture.2008.10.006

2008

• Changes in the immune response and metabolic fingerprint of the mussel, Mytilus edulis (Linnaeus) in response to lowered salinity and physical stress.
  
  Bussell, JA, Gidman, EA, Causton, DR, Gwynn-Jones, D, Malham, SK, Jones, ML, Reynolds, B & Seed, R 2008, 'Changes in the immune response and metabolic fingerprint of the mussel, Mytilus edulis (Linnaeus) in response to lowered salinity and physical stress.' Journal of Experimental Marine Biology and Ecology, vol. 358, no. 1, pp. 78-85. DOI: 10.1016/j.jembe.2008.01.018

2007

• A methodology for screening haemolymph of intertidal mussels, Mytilus edulis, using FT-IR spectroscopy as a tool for environmental assesment.
  
  Gidman, EA, Jones, ML, Bussell, JA, Malham, S, Reynolds, B, Seed, R, Causton, DR, Johnson, HE & Gwynn-Jones, D 2007, 'A methodology for screening haemolymph of intertidal mussels, Mytilus edulis, using FT-IR spectroscopy as a tool for environmental assesment.' Metabolomics, vol. 3, no. 4, pp. 465-473. DOI: 10.1007/s11306-007-0060-8

2006

• Growth of Crassostrea gigas spat and juveniles under differing environmental conditions at two sites in Wales
  
  King, JW, Malham, SK, Skov, MW, Cotter, E, Latchford, JW, Culloty, SC & Beaumont, AR 2006, 'Growth of Crassostrea gigas spat and juveniles under differing environmental conditions at two sites in Wales' Aquatic Living Resources, vol. 19, no. 3, pp. 289-297. DOI: 10.1051/alr:2006030
• Fishing for Cephalopods
  
  Pierce, G, Valavanis, V, Pereira, J, Santurtun, M, Robin, JP & Malham, SK 2006, 'Fishing for Cephalopods' ICES CIEM Newsletter, vol. 43, pp. 13-15.
• Immunology of the mussel Mytilus edulis: a toolkit for environmental managers.
  
  Bussell, JA, Oliver, LR, Malham, SK, Jones, ML, Reynolds, B, Gidman, EA, Gwynn-Jones, D & Seed, R 2006, 'Immunology of the mussel Mytilus edulis: a toolkit for environmental managers.' Paper presented at 41st European Marine Biology Symposium, University of Cork, 3/01/01, .
• Testing the response of oysters exposed to chemicals X, Y, and Z
  
  Malham, SK, Walton, MW, Latchford, JW, King, JW & Greenwell, HC 2006, Testing the response of oysters exposed to chemicals X, Y, and Z. 2006 edn, Centre for Applied Marine Sciences.

2005

• Mortality of Pacific oysters in the Irish Sea: Biotic and abiotic influences
  
  Cotter, E, Culloty, SC, O'Keeffe, S, Malham, SK, Latchford, JW, King, JW & Beaumont, AR 2005, 'Mortality of Pacific oysters in the Irish Sea: Biotic and abiotic influences' Journal of Shellfish Research, vol. 24, no. 2, pp. 648.
• Effects of terrestrial agriculture on marine biodiversity.
  
  Bussell, JA, Malham, SK, Jones, ML, Reynolds, B, Gidman, EA, Gwynn-Jones, D & Seed, R 2005, 'Effects of terrestrial agriculture on marine biodiversity.' Paper presented at 39th Meeting of the Estuaries and Coastal Sciences Association, University of Edinburgh., 3/01/01, .

2002

• Stress-induced immune changes in the oyster Crassostrea gigas.
  
  Lacoste, A, Malham, SK, Gelebart, F, Cueff, A & Poulet, SA 2002, 'Stress-induced immune changes in the oyster Crassostrea gigas.' Developmental and Comparative Immunology, vol. 26, no. 1, pp. 1-9. DOI: 10.1016/S0145-305X(01)00067-2

2001

• Noradrenaline reduces the stimulatory effect of interleukin-1 alpha on reactive oxygen species production by oyster immunocytes
  
  Lacoste, A, Malham, SK, Cueff, A & Poulet, SA 2001, 'Noradrenaline reduces the stimulatory effect of interleukin-1 alpha on reactive oxygen species production by oyster immunocytes' Invertebrate Biology, vol. 120, no. 4, pp. 358-364. DOI: 10.1111/j.1744-7410.2001.tb00043.x
• Vibrio splendidus strain is associated with summer mortality of juvenile oysters Crassostrea gigas in the Bay of Morlaix (North Brittany, France)
  
  Lacoste, A, Jalabert, F, Malham, SK, Cueff, A, Gelebart, F, Cordevant, C, Lange, M & Poulet, SA 2001, 'Vibrio splendidus strain is associated with summer mortality of juvenile oysters Crassostrea gigas in the Bay of Morlaix (North Brittany, France)' Diseases of Aquatic Organisms, vol. 46, no. 2, pp. 139-145. DOI: 10.3354/dao046139
• Noradrenaline modulates oyster hemocyte phagocytosis via a beta-adrenergic receptor-cAMP signaling pathway
  
  Lacoste, A, Malham, SK, Cueff, A & Poulet, SA 2001, 'Noradrenaline modulates oyster hemocyte phagocytosis via a beta-adrenergic receptor-cAMP signaling pathway' General and Comparative Endocrinology, vol. 122, no. 3, pp. 252-259. DOI: 10.1006/gcen.2001.7643
• Noradrenaline modulates hemocyte reactive oxygen species production via beta–adrenergic receptors in the oyster Crassostrea gigas.
  
  Lacoste, A, Malham, SK, Cueff, A & Poulet, SA 2001, 'Noradrenaline modulates hemocyte reactive oxygen species production via beta–adrenergic receptors in the oyster Crassostrea gigas.' Developmental and Comparative Immunology, vol. 25, no. 4, pp. 285-289. DOI: 10.1016/S0145-305X(00)00067-7
• Stress and stress-induced neuroendocrine changes increase the susceptibility of juvenile oysters (Crassostrea gigas) to Vibrio splendidus.
  
  Lacoste, A, Jalabert, F, Malham, SK, Cueff, A & Poulet, SA 2001, 'Stress and stress-induced neuroendocrine changes increase the susceptibility of juvenile oysters (Crassostrea gigas) to Vibrio splendidus.' Applied and Environmental Microbiology, vol. 67, no. 5, pp. 2304-2309. DOI: 10.1128/AEM.67.5.2304-2309.2001
• Stress-induced catecholamine changes in the hemolymph of the oyster Crassostrea gigas.
  
  Lacoste, A, Malham, SK, Cueff, A & Poulet, SA 2001, 'Stress-induced catecholamine changes in the hemolymph of the oyster Crassostrea gigas.' General and Comparative Endocrinology, vol. 122, no. 2, pp. 181-188. DOI: 10.1006/gcen.2001.7629
• Evidence for a form of adrenergic response to stress in the oyster Crassostrea giga.
  
  Lacoste, A, Malham, SK, Cueff, A, Jalabert, F, Gelebart, F & Poulet, SA 2001, 'Evidence for a form of adrenergic response to stress in the oyster Crassostrea giga.' Journal of Experimental Biology, vol. 204, no. 7, pp. 1247-1255.