Module FXX-2208:
Integrated Chemistry Labs

Module Facts

Run by School of Natural Sciences

40 Credits or 20 ECTS Credits

Semester 1 & 2

Organiser: Dr Enlli Harper

Overall aims and purpose

Students should develop quantitative and qualitative laboratory skills; and skills to record and interpret scientific observations. Students should gain an awareness of safe and diligent laboratory practice and foster communication, planning and time management skills. The module will establish and develop problem-solving and critical thinking skills, the ability to use conceptual models to rationalize observations, a capacity to articulate knowledge and understand written presentation. The module is designed to extend the transferable skills desirable in a professional chemist by: 1. Developing essential communication and group working skills for a professional chemist. 2. Developing essential skills for a professional chemist in computational chemistry.

Course content

CORE MODULE. This module is CORE to your degree programme. In order to progress to the next year of study you MUST successfully complete and pass this module. (There are NO resits for practical modules).

The course is divided between five areas, namely analytical chemistry (AAS, UV, GC, NMR, HPLC data analysis), computational chemistry, inorganic chemistry (preparation and analysis of hexamine cobalt(III) chloride, phosphine complexes of nickel(II), characterisation of an iron haem protein: myoglobin, preparation of [BF4-] compounds), organic (glycoside, polymer, sugar and Wittig chemistries and olefin metathesis), and physical chemistry (acetone-iodine reaction kinetics, critical micelle concentration, electrochemistry, absorption spectrum of iodine and silver nanoprisms) with a series of experiments in each discipline, reinforcing chemistry covered in the core chemistry modules.

Course Team: Dr Enlli Harper Teaching & Laboratory Academic (Laboratory Supervision) Introductory Lectures Semester 1 : Dr L Jones, Dr J Al-Dulayymi, Dr E Harper, Dr M Lahmann, Dr C Gwenin, Prof M Beckett, Dr V Thoss, Dr L Murphy Introductory Lectures in Semester 2 : Dr P Murphy, Dr L Jones, Prof M Beckett, Dr J Al-Dulayymi, Dr K Hughes, Dr J Thomas, Dr C Gwenin, Dr H Tai, Dr R Davies

RESOURCE IMPLICATIONS ESSENTIAL READING 1. Experimental Organic Chemistry: Preparative and Microscale. Laurence M. Harwood, Christopher J. Moody, Jonathan M. Percy. 1998 - Wiley RECOMMENDED READING 2. Practical Skills in Chemistry (2nd Edition) 2011 John Dean, Alan M Jones , David Holmes , Rob Reed, Allan Jones, Jonathan Weyers 3. Chemical Analysis - Modern Instrumentation, Methods and Techniques. F. Rouessac and A, Rouessac 2007 4. Spectrometric Identification of Organic Compounds. by Silverstein, Bassler and Morrill (Wiley) Most recent edition of this as it is regularly updated. SPECIFIC RESOURCE IMPLICATIONS FOR STUDENTS - None It is expected that students will purchase or have ready access to the essential text books above

Assessment Criteria

threshold

Threshold (40%). Standard laboratory experiments are usually carried out with reasonable success though significance and limitations of experimental data and/or observations may not be fully recognised; Transferable skills are at a basic level.

good

Good (~60%). Experimental work is carried out in a reliable and efficient manner, with a good appreciation of data analysis shown in write-ups. Performance in transferable skills is sound and shows no significant deficiencies.

excellent

Excellent (>70%). Experimental work are exemplary and show a thorough analysis and appraisal of experimental results, with appropriate suggestions for improvement. Performance in transferable skills is generally very good.

Learning outcomes

  1. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) qualitative analysis skills.

  2. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) quantitative analysis skills.

  3. Students should be able to demonstrate: core communication skills (oral presentation and scientific poster) on a chemistry topic.

  4. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) and develop problem solving and critical thinking skills.

  5. Students should be able to demonstrate extended computational skills.

  6. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) health and safety skills.

  7. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) laboratory manipulative skills

  8. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) recording and interpretation of scientific observations.

  9. Students should be able to demonstrate (in relation to the experiments described in the summary of course content) communication/planning/time management/receiving and comprehending complex information skills.

Assessment Methods

Type Name Description Weight
Daily Caffeine and Vitamin C intake 5.45
Determination of alcohol in beers 2.5
Stereochemistry of a benzoin reduction (LAB) 5.45
Stereochemistry of a benzoin reduction (COMP) 2.5
MINI REPORT: Knoevenagel condensation 5.5
Critical Micelle Concentration 5.45
Kinetics 5.45
Preparation of [BF4]- compounds 5.45
Sugar Chemistry: in lab assignment 2.5
Determination of calcium: EDTA titration and AAS 2.5
POSTER: Haem Chemistry 2.5
Stereochemistry of the Wittig reaction: in lab assignment 2.5
Phosphine complexes of Ni(II): in lab assignment 2.5
Cobalt 5.45
Olefin Metathesis 10.9
Absorption spectrum of iodine 5.45
Silver Nanoprisms: in lab assignment 2.5
MINI REPORT: Sugars (NMR) 5.45
Polymer Chemistry: in lab assignment 2.5
Computational Chemistry 1: in lab assignment 2.5
Computational Chemistry 2: in lab assignment 2.5
PRESENTATION 2.5
Laboratory Skills 10

Teaching and Learning Strategy

Hours
Lecture

Lectures (21 x 1h)

21
Laboratory

19 x (3 x 3h) 2 x (2 x 3h)

183
Workshop

2 x (3 x 3h) 1 x (1 x 3h)

21
Private study 175

Transferable skills

  • Literacy - Proficiency in reading and writing through a variety of media
  • Numeracy - Proficiency in using numbers at appropriate levels of accuracy
  • Critical analysis & Problem Solving - Able to deconstruct and analyse problems or complex situations. To find solutions to problems through analyses and exploration of all possibilities using appropriate methods, rescources and creativity.
  • Safety-Consciousness - Having an awareness of your immediate environment, and confidence in adhering to health and safety regulations
  • Presentation - Able to clearly present information and explanations to an audience. Through the written or oral mode of communication accurately and concisely.
  • Teamwork - Able to constructively cooperate with others on a common task, and/or be part of a day-to-day working team

Subject specific skills

  • CC3 Skills in the practical application of theory using computational methodology and models
  • CC4 The ability to recognise and analyse problems and plan strategies for their solution
  • CC5 Skills in the generation, evaluation, interpretation and synthesis of chemical information and data
  • CC6 Skills in communicating scientific material and arguments
  • CC7 Information technology and data-processing skills, relating to chemical information and data.
  • CC8 The ability to adapt and apply methodology to the solution of unfamiliar problems
  • CP1 An ability to determine hazards associated with carrying out chemical experiments in terms of chemical toxicity, chemical stability and chemical reactivity and be able to find information to enable effective risk assessments to be carried out
  • CP2 Skills to handle chemicals safely and carry out experiments and chemical reactions in asafe manner, based on effective risk assessments
  • CP3 Skills required for the conduct of documented laboratory procedures involved in synthesis and analysis, in relation to both inorganic and organic systems
  • CP4 Skills in the monitoring, by observation and measurement, of chemical properties, events or changes, and the systematic and reliable recording and documentation thereof
  • CP5 Skills in the operation of standard chemical instrumentation
  • CP7 The ability to interpret and explain the limits of accuracy of their own experimental data in terms of significance and underlying theory
  • PS1 Communication skills, covering both written and oral communication with a variety of audiences
  • PS2 Skills in the employment of common conventions and standards in scientific writing, data presentation, and referencing literature
  • PS3 Problem-solving skills, relating to qualitative and quantitative information
  • PS4 Numeracy and mathematical skills, including handling data, algebra, functions, trigonometry, calculus, vectors and complex numbers, alongside error analysis, order-of-magnitude estimations, systematic use of scientific units and different types of data presentation
  • PS5 Information location and retrieval skills, in relation to primary and secondary information sources, and the ability to assess the quality of information accessed
  • PS7 Basic interpersonal skills, relating to the ability to interact with other people and to engage in teamworking
  • PS8 Time management and organisational skills, as evidenced by the ability to plan and implement efficient and effective ways of working
  • PS11 Problem-solving skills including the demonstration of self-direction, initiative and originality
  • SK2 Demonstrate a systematic understanding of fundamental physicochemical principles with the ability to apply that knowledge to the solution of theoretical and practical problems
  • PS16 The ability to work in multi-disciplinary and multi-skilled teams
  • SK4 Demonstrate, with supporting evidence, their understanding of synthesis, including related isolation, purification and characterisation techniques
  • SK5 Demonstrate an understanding of the qualitative and quantitative aspects of chemical metrology and the importance of traceability
  • SK8 Develop an understanding of safe working practice, in terms of managing chemical toxicity, chemical stability andchemical reactivity, through knowledge-based risk assessments
  • SK9 Read and engage with scientific literature
  • CC1 the ability to demonstrate knowledge and understanding of essential facts,concepts,principles and theories relating to theSubject areasCovered in theirProgramme
  • CC2 the ability to applysuch knowledge and understanding to thesolution of qualitative and quantitativeProblems that are mostly of a familiar nature

Resources

Courses including this module