Module MSE-2016:
Basic Clinical Biochemistry

Module Facts

Run by School of Medical Sciences

10 Credits or 5 ECTS Credits

Semester 1

Organiser: Miss Alyson Moyes

Overall aims and purpose

The aim of this module is to introduce students to the laboratory methods used in Clinical Biochemistry in diagnosis and monitoring of organ functions.

Course content

Investigations on blood and other biological materials to aid the diagnosis of metabolic diseases, and monitoring of therapy. Topics to include Diabetes, Liver function and Clinical Endocrinology. Practical work will include an introduction to the investigative laboratory methods used in Clinical Biochemistry.

Assessment Criteria

C- to C+

Category C (50%-59%):

A less engaged student would have a correct knowledge of clinical biochemistry, but answers lack context and detail. Written answers should demonstrate an ability to organise relevant lecture material into a coherent argument.

excellent

Category A (70%-100%):

Written answers should have an extremely high standard of presentation, structure and clarity with a very well argued and coverage of accurate and relevant information from lecture notes and significant background reading.

Evidence of wider reading & critical thinking is required for A+ and A* marks.

threshold

Category D (40%-49%):

A threshold student should have a basic knowledge of the essential facts and key concepts of Clinical Biochemistry presented in this module. Written answers should demonstrate an ability to organise relevant lecture material into a coherent argument. Answers may reveal knowledge gaps and errors.

good

Category B (60%-69%):

A good student should have a thorough factual knowledge across all aspects of the module, and be able to detail examples where appropriate. Written answers should demonstrate an ability to synthesise lecture material. Limited evidence of background reading.

Learning outcomes

  1. Understand the principles of the most frequently used pathology laboratory tests used in clinical biochemistry and their diagnostic significance

  2. Explain the theory and practical aspects of clinical biochemistry

  3. Demonstrate an understanding of the basic laboratory investigations used in diagnostic clinical biochemistry

Assessment Methods

Type Name Description Weight
EXAM End of module MCQ exam

A summative MCQ paper to test all of the semester 1 taught content.

60
COURSEWORK Lab Practical report

The objective of this practical is to use an enzymatic method for the determination of plasma glucose. An assessment of the accuracy and imprecision of the analytical method is undertaken in addition to analysis of samples taken from two patients who have undergone a glucose tolerance test (GTT) for suspected Diabetes Mellitus.

40

Teaching and Learning Strategy

Hours
Lecture

8 x 2 hour lectures

16
Tutorial

1 x 2 hour revision for end of module exam with mock MCQ exam

2
Private study

Directed and self directed reading around the topic to supplement lecture matereal. Practical report write up. Revision for mid module test and end of module exam.

78
Practical classes and workshops

Laboratory practical session utilising some diagnostic tests used in the Clinical Biochemistry setting.

4

Transferable skills

  • Literacy - Proficiency in reading and writing through a variety of media
  • Numeracy - Proficiency in using numbers at appropriate levels of accuracy
  • Self-Management - Able to work unsupervised in an efficient, punctual and structured manner. To examine the outcomes of tasks and events, and judge levels of quality and importance
  • Exploring - Able to investigate, research and consider alternatives
  • Information retrieval - Able to access different and multiple sources of information
  • Inter-personal - Able to question, actively listen, examine given answers and interact sensitevely with others
  • Critical analysis & Problem Solving - Able to deconstruct and analyse problems or complex situations. To find solutions to problems through analyses and exploration of all possibilities using appropriate methods, rescources and creativity.
  • Safety-Consciousness - Having an awareness of your immediate environment, and confidence in adhering to health and safety regulations
  • Presentation - Able to clearly present information and explanations to an audience. Through the written or oral mode of communication accurately and concisely.
  • Teamwork - Able to constructively cooperate with others on a common task, and/or be part of a day-to-day working team
  • Argument - Able to put forward, debate and justify an opinion or a course of action, with an individual or in a wider group setting
  • Self-awareness & Reflectivity - Having an awareness of your own strengths, weaknesses, aims and objectives. Able to regularly review, evaluate and reflect upon the performance of yourself and others

Subject specific skills

Biomedical Science benchmarks:

The programme aims to give students a comprehension of scientific investigation of blood sciences. (benchmarks: 5.1; 5.3; 5.5)

On successful completion of the course, students will be able to engage with essential facts, major concepts, principles and theories associated with blood sciences, and understand the biological mechanisms underlying human pathological conditions and the basis of the analytical techniques used to diagnose and monitor these conditions. (benchmark: 6.4)

Biomedical Science benchmarks:

The programme aims to give students a comprehension of scientific investigation of Clinical Biochemistry. (benchmarks: 5.1; 5.3; 5.5)

On successful completion of the course, students will be able to engage with essential facts, major concepts, principles and theories associated with clinical biochemistry, and understand the biological mechanisms underlying human pathological conditions and the basis of the analytical techniques used to diagnose and monitor these conditions. (benchmark: 6.4)

Be able to undertake practical investigations in a responsible, safe and ethical manner while paying attention to risk assessment, relevant health and safety regulations, ethical issues, procedures for obtaining ethical permission and informed consent and issues relating to patient welfare. (benchmark: 4.3)

Graduates will be able to apply their knowledge to a professional, evidence-based approach to research into the pathogenesis and origins of disease processes. (benchmark: 6.2)

Biomedical science graduates are aware of the current laboratory methods to investigate and diagnose human diseases in clinical and research environments. This includes an appreciation of research and the development of new technologies. (benchmark: 6.3)

Biomedical sciences graduates should recognise and apply subject-specific theories, paradigms, concepts or principles to reach evidence-based decisions. (benchmark: 4.2)

To be able to receive and respond to a variety of sources of information (textual, numerical, verbal, graphical), carry out sample selection, produce record scientific records & analyse data within a statistical context (an understanding of statistical significance and statistical power), and to communicate the outcomes to a variety of audiences using a range of formats, media and approaches including the avoidance of plagiarism. (benchmark: 4.4; 4.5)

Graduates should develop the skills necessary for self-managed and lifelong learning, have an appreciation for the role and impact of intellectual property, and identify and work towards targets for personal, academic, professional and career development. (benchmark: 4.7)

Graduates will be able to apply their knowledge to a professional, evidence-based approach to research into the pathogenesis and origins of disease processes. (benchmark: 6.2)

Biomedical science graduates are aware of the current laboratory methods to investigate and diagnose human diseases in clinical and research environments. This includes an appreciation of research and the development of new technologies. (benchmark: 6.3)

Biomedical sciences graduates should recognise and apply subject-specific theories, paradigms, concepts or principles to reach evidence-based decisions. (benchmark: 4.2)

To be able to receive and respond to a variety of sources of information (textual, numerical, verbal, graphical), carry out sample selection, produce record scientific records & analyse data within a statistical context (an understanding of statistical significance and statistical power), and to communicate the outcomes to a variety of audiences using a range of formats, media and approaches including the avoidance of plagiarism. (benchmark: 4.4; 4.5)

Graduates should develop the skills necessary for self-managed and lifelong learning, have an appreciation for the role and impact of intellectual property, and identify and work towards targets for personal, academic, professional and career development. (benchmark: 4.7) Additional subject specific skills not listed above.

Resources

Talis Reading list

http://readinglists.bangor.ac.uk/modules/mse-2016.html

Reading list

Clinical biochemistry - Nessar Ahmed c2011 (Book Testyn Craidd - Core Text)

Tietz fundamentals of clinical chemistry and molecular diagnostics - Carl A. Burtis, David E. Bruns, Norbert W. Tietz 2015 (Book Argymhellir ei ddarllen - Recommended Reading)