Module MSE-3015:
Haematology

Module Facts

Run by School of Medical Sciences

10 Credits or 5 ECTS Credits

Semester 2

Organiser: Dr Dylan Jones

Overall aims and purpose

The aim of this module is to develop the knowledge and skills gained in MSE-2015 Yr2 Haematology and Blood transfusion. The morphology and physiology of blood and its constituents and the study of blood coagulation will be developed to include abnormal haematological conditions and diseases. The main haematological diseases will be discussed in depth, including myelodysplasia, leukaemias, lymphomas, and haemoglobinopathies.

During the course of the module students will learn holistically about the role of haematology in patient diagnosis and treatment. Students will be exposed to the latest developments in both diagnosis (including the role of molecular methodologies in health care) and treatment (such as the use of haemopoietic stem cell transplants and monoclonal antibody therapy).

This module is available to International exchange students of The College of Health and Behavioural Sciences

Please note: This module is a core component of the School of Medical Sciences accredited Biomedical Sciences degree programs. As such students without appropriate pre-requisite background knowledge and understanding of human molecular and cellular biology may find the module content and assessments, challenging.

To enhance learning and understanding, lectures, tutorials and practical demonstrations are recorded using the Panopto system where available.

Course content

This module will cover several key aspects of haematological disease and therapeutic options. Lectures and revision sessions will present detailed information and discussion on key issues relating to clinical haematology. Links to cutting edge developments and research will be highlighted and a reflection on how clinical and diagnostic patterns have changed over time. The module will contain lectures on the following topics:

  • Lymphoblastic leukaemia.
  • Myeloid leukaemia.
  • Myelodysplasia.
  • Lymphoma and myeloma.
  • Haemoglobinopathies.
  • Haematology of disease.
  • Stem Cell Transplant.
  • Applied Blood Transfusion.

Practical experience of key haematological tests will be delivered through a case study based practical session. Students will be expected to be able to recognise and diagnose key haematological malignancies and conduct routine blood typing experiments.

Assessment Criteria

C- to C+

Category C (50%-59%):

A C category student should have a correct understanding of the essential facts and key concepts in haematology and blood transfusion presented in this module. Written answers should demonstrate an ability to organise relevant lecture material into a coherent argument. The argument may reveal knowledge gaps. Context and explanation may be missing. No evidence of wider reading.

threshold

Category D (40%-49%):

A threshold student should have a basic knowledge of the essential facts and key concepts in haematology and blood transfusion presented in this module. Written answers should demonstrate an ability to organise relevant lecture material into a coherent argument.

excellent

Category A (70%-100%):

An excellent student should be able to demonstrate the skills necessary for self-managed and lifelong learning (working independently, time management and organisation) and have a detailed in depth knowledge of all aspects of the module. Written answers should have an extremely high standard of presentation, structure and clarity with a very well argued and coverage of accurate and relevant information from lecture notes and significant background reading.

good

Category B (60%-69%):

A good student should have a thorough factual knowledge across all aspects of the module, and be able to detail examples where appropriate. Written answers should demonstrate an ability to critically synthesise lecture material and information from background reading.

Learning outcomes

  1. Critically discuss the role of blood products and haemopoeitic stem cell transplants as therapeutic interventions.

  2. Summarize the most frequently used pathology laboratory tests used in haematology and blood transfusion and their diagnostic significance

  3. Critically discuss the types, causes and diagnosis of anaemias, leukaemias and haemoglobinioipathies.

  4. Critically evaluate the role of molecular diagnostics in haematology.

Assessment Methods

Type Name Description Weight
REPORT Practical Report

A case study based practical containing blood typing and morphology based skills.

30
EXAM Final module exam

An essay based exam in which you choose 2 essays out of 4 potential questions.

70

Teaching and Learning Strategy

Hours
Tutorial

1x 2h Revision for final exam 1x 2h Essay writing Practice

4
Lecture

8x 2h Interactive lectures

16
Practical classes and workshops

Practical session in the C4 (Cat II) Laboratory.

3
Private study

Directed and self directed reading of information around the topics to supplement lecture material. Write the practical report. Revision for the final exam

77

Transferable skills

  • Literacy - Proficiency in reading and writing through a variety of media
  • Numeracy - Proficiency in using numbers at appropriate levels of accuracy
  • Self-Management - Able to work unsupervised in an efficient, punctual and structured manner. To examine the outcomes of tasks and events, and judge levels of quality and importance
  • Exploring - Able to investigate, research and consider alternatives
  • Information retrieval - Able to access different and multiple sources of information
  • Inter-personal - Able to question, actively listen, examine given answers and interact sensitevely with others
  • Critical analysis & Problem Solving - Able to deconstruct and analyse problems or complex situations. To find solutions to problems through analyses and exploration of all possibilities using appropriate methods, rescources and creativity.
  • Safety-Consciousness - Having an awareness of your immediate environment, and confidence in adhering to health and safety regulations
  • Presentation - Able to clearly present information and explanations to an audience. Through the written or oral mode of communication accurately and concisely.
  • Teamwork - Able to constructively cooperate with others on a common task, and/or be part of a day-to-day working team
  • Argument - Able to put forward, debate and justify an opinion or a course of action, with an individual or in a wider group setting
  • Self-awareness & Reflectivity - Having an awareness of your own strengths, weaknesses, aims and objectives. Able to regularly review, evaluate and reflect upon the performance of yourself and others

Subject specific skills

Biomedical Science benchmarks:

The programme aims to give students a comprehension of scientific investigation of haematology. (benchmarks: 5.1; 5.3; 5.5)

On successful completion of the course, students will be able to engage with essential facts, major concepts, principles and theories associated with blood sciences and to understand the biological mechanisms underlying human pathological conditions and the basis of the analytical techniques used to diagnose and monitor these conditions. (benchmark: 6.4)

Graduates will be able to apply their knowledge to a professional, evidence-based approach to research into the pathogenesis and origins of disease processes. (benchmark: 6.2)

Biomedical science graduates are aware of the current laboratory methods to investigate and diagnose human diseases in clinical and research environments. This includes an appreciation of research and the development of new technologies. (benchmark: 6.3)

Biomedical sciences graduates should recognise and apply subject-specific theories, paradigms, concepts or principles to reach evidence-based decisions. (benchmark: 4.2)

To be able to receive and respond to a variety of sources of information (textual, numerical, verbal, graphical), carry out sample selection, produce record scientific records & analyse data within a statistical context (an understanding of statistical significance and statistical power), and to communicate the outcomes to a variety of audiences using a range of formats, media and approaches including the avoidance of plagiarism. (benchmark: 4.4; 4.5)

Graduates should develop the skills necessary for self-managed and lifelong learning, have an appreciation for the role and impact of intellectual property, and identify and work towards targets for personal, academic, professional and career development. (benchmark: 4.7)

Resources

Pre- and Co-requisite Modules