Skip to main content
Home

Information for:

  • Alumni
  • Applicants
  • Current Students
  • Staff
  • Parents
  • Job Vacancies
  • Covid-19
  • Cymraeg
My country:

Main Menu

    • Study Options
      • Study Home
      • Why Study at Bangor?
      • Undergraduate Study
      • Postgraduate Taught Study
      • Postgraduate Research
      • Executive Education
      • Part-time Courses
      • January Start Courses
      • Degree Apprenticeships
      • Study Abroad
      • Work Experience
    • Study Advice
      • Apply
      • Already Applied?
      • Fees and Finances
      • Scholarships and Bursaries
      • Get Ready for University
      • Widening Access
    • Explore Bangor
      • Open Days and Visits
      • Virtual Student Experience
      • Magical Bangor

    Find a Course

    Order a Course Guide

    Open Days

    Clearing

    • Student Life
      • Student Life Home
      • Bangor and the Area
      • Social Life and Entertainment
      • Student Accommodation
      • Clubs and Societies
      • Sport
      • Virtual Student Experience
      • Videos and Vlogs
    • Your Experience at Bangor
      • Student Support
      • Skills and Employability
      • Study or Work Abroad
      • Fees and Finances

    Student Profiles

    Student Videos and Vlogs

    Welcome 2022

    • Choose Bangor
      • International Home
      • Why Bangor?
      • Location
      • Accommodation
      • Student Support
      • Contact Us
      • Bangor University's China website
    • Apply
      • Entry Requirements
      • Tuition Fees and Scholarships
      • How to Apply
      • Already Applied
      • Study Abroad
      • Exchanges
      • Worldwide Partners

    Country Specific Information

    Bangor University International College

    Find a Course

    Clearing 2023

    • Research
      • Research Home
      • About Our Research
      • Research in our Academic Schools
      • Research Institutes and Centres
      • Research Portal
      • Integrated Research and Impact Support (IRIS) Service
      • Energy
      • REF 2021
      • Research News
    • Postgraduate Research Opportunities
      • Postgraduate Research
      • Doctoral School
    • Events and Training Opportunities
      • Researcher Development
    • The University
      • About Us
      • Our Mission
      • Strategy 2030
      • Annual Report & Financial Statements
      • Our Location
      • Academic Schools and Colleges
      • Services and Facilities
      • Vice-Chancellor's Office
      • Working with Business
      • Working with the Community
      • Sustainability
      • Health and Wellbeing
      • Contact Us
    • Working for Us
      • Job Vacancies
    • University Management and Governance
      • Policies and Procedures
      • Slavery and Human Trafficking Statement
      • Management and Governance
    • University and the Community
      • Pontio
      • Sports Facilities
      • Conference Facilities
      • Places to Eat and Drink
      • Public Events
      • Widening Access
      • Services to Schools
    • Business Services
      • Business Services Home
    • Collaboration Hub
      • Collaboration Hub
    • Conferencing and Business Dining
      • Conferencing Facilities
      • Business Dining
    • Intellectual Property (IP) and Commercialisation
      • Intellectual Property (IP) and Commercialisation
    • News
      • Current News
      • Research News
      • Student News
    • Events
      • Events
    • Announcements
      • Flag Announcements
  • Open Days

    • Study Options
      • Study Home
      • Why Study at Bangor?
      • Undergraduate Study
      • Postgraduate Taught Study
      • Postgraduate Research
      • Executive Education
      • Part-time Courses
      • January Start Courses
      • Degree Apprenticeships
      • Study Abroad
      • Work Experience
    • Study Advice
      • Apply
      • Already Applied?
      • Fees and Finances
      • Scholarships and Bursaries
      • Get Ready for University
      • Widening Access
    • Explore Bangor
      • Open Days and Visits
      • Virtual Student Experience
      • Magical Bangor

    Find a Course

    Order a Course Guide

    Open Days

    Clearing

    • Student Life
      • Student Life Home
      • Bangor and the Area
      • Social Life and Entertainment
      • Student Accommodation
      • Clubs and Societies
      • Sport
      • Virtual Student Experience
      • Videos and Vlogs
    • Your Experience at Bangor
      • Student Support
      • Skills and Employability
      • Study or Work Abroad
      • Fees and Finances

    Student Profiles

    Student Videos and Vlogs

    Welcome 2022

    • Choose Bangor
      • International Home
      • Why Bangor?
      • Location
      • Accommodation
      • Student Support
      • Contact Us
      • Bangor University's China website
    • Apply
      • Entry Requirements
      • Tuition Fees and Scholarships
      • How to Apply
      • Already Applied
      • Study Abroad
      • Exchanges
      • Worldwide Partners

    Country Specific Information

    Bangor University International College

    Find a Course

    Clearing 2023

    • Research
      • Research Home
      • About Our Research
      • Research in our Academic Schools
      • Research Institutes and Centres
      • Research Portal
      • Integrated Research and Impact Support (IRIS) Service
      • Energy
      • REF 2021
      • Research News
    • Postgraduate Research Opportunities
      • Postgraduate Research
      • Doctoral School
    • Events and Training Opportunities
      • Researcher Development
    • The University
      • About Us
      • Our Mission
      • Strategy 2030
      • Annual Report & Financial Statements
      • Our Location
      • Academic Schools and Colleges
      • Services and Facilities
      • Vice-Chancellor's Office
      • Working with Business
      • Working with the Community
      • Sustainability
      • Health and Wellbeing
      • Contact Us
    • Working for Us
      • Job Vacancies
    • University Management and Governance
      • Policies and Procedures
      • Slavery and Human Trafficking Statement
      • Management and Governance
    • University and the Community
      • Pontio
      • Sports Facilities
      • Conference Facilities
      • Places to Eat and Drink
      • Public Events
      • Widening Access
      • Services to Schools
    • Business Services
      • Business Services Home
    • Collaboration Hub
      • Collaboration Hub
    • Conferencing and Business Dining
      • Conferencing Facilities
      • Business Dining
    • Intellectual Property (IP) and Commercialisation
      • Intellectual Property (IP) and Commercialisation
    • News
      • Current News
      • Research News
      • Student News
    • Events
      • Events
    • Announcements
      • Flag Announcements
  • Open Days

Information for:

  • Alumni
  • Applicants
  • Current Students
  • Staff
  • Parents
  • Job Vacancies
  • Covid-19
My country:

Search

Close

Breadcrumb

  • Cymraeg

Share this page:
  • Twitter
  • Facebook
  • LinkedIn

Apply Now

Find out how to apply

Open Days

More information

Order a Course Guide

Order Now

Request Information

Get in touch

Chat to our staff and students

Connect through Unibuddy

Module MSE-4081:
OMICS

Omics Techniques and Technologies 2024-25
MSE-4081
2024-25
North Wales Medical School
Module - Semester 1
20 credits
Module Organiser: Andrew Pierce
Overview

This module will explore how information from the transcriptome, metabolome and proteome can be applied to the interpretation of genomic information. This will include: the basis of genotyping and detection of genetic variation; and the strategies employed for evaluating pathogenicity of variants for clinical reporting. Students will be taught; the methodologies employed for whole exome and whole genome sequencing; the methodologies to assess the transcriptome; methodologies to assess the metabolome and proteome. The module will also demonstrate the importance of metabolomics and proteomics for the functional interpretation of genomic data and discovery of disease biomarkers.

Topics will be presented via lectures, seminars, study groups work-based learning and tutorials. The syllabus will include topics such as: • The basis of genotyping and detection of genetic variation. • Whole exome and whole genome sequencing, including library preparation methods, sequencing chemistries and platforms • Genomic testing strategies as: gene focused, multiple genes, or whole genome or exome, and for detection of sequence, copy number or rearrangements • An overview of the methodologies to assess the transcriptome, including RNA expression profiling and sequencing
• A brief introduction into the methodologies employed to assess the metabolome and proteome. • How information from the transcriptome, metabolome and proteome can be applied to the interpretation of genomic information. • Approaches to the evaluation of pathogenicity of variants in the context of an NHS clinical report.

Assessment Strategy

-threshold -Pass (C- to C+) (range 50-59%)Primary criteriaA pass level demonstrates knowledge and comprehension of key areas & principles, with understanding of the main elements of the subject area, although gaps and weaknesses in the argument are evident. No real evidence of background study and wider reading is evident. Answers are focussed on questions but also with some irrelevant material and weaknesses in structure & argument. Answers have several factual/computational errors. Lack of originality and interpretation. No links between topics are described. Limited problem solving skills. Some weaknesses in presentation accuracy & delivery.Secondary CriteriaC+ Good within the class - Exceeds expectations for some primary criteria - Strong factual knowledge with some weaknesses in understanding - Ideas/arguments are limited but are well presentedC Mid-level - Matches all primary criteria - Moderate factual knowledge with some weaknesses in understanding - Ideas/arguments are limited presented with weaknesses in logic/presentationC- Meets requirements of class - Matches most but not all primary criteria - Moderate factual knowledge with several weaknesses in understanding - Ideas/arguments are limited presented with weaknesses in logic/presentation

-good -Merit (B- to B+) (range 60-69%)Primary criteriaGood students demonstrate strong knowledge & understanding of most but not all of the subject area. Limited evidence of background study. The answers are focussed with good structure. Arguments are presented coherently, mostly free of factual/computational errors. Some limited original interpretation. Well know links between topics are described. Problems are addressed by existing methods/approaches. Good presentation with accurate communicationSecondary CriteriaB+ Good - Exceeds expectations for most primary criteria - Command of subject but with gaps in knowledge - Some ideas/arguments originalB Mid-level - Meets all primary criteria - Strong factual knowledge and understanding - Ideas/arguments are well presented by few are originalB- Meets requirements of class - Meets most but not all primary criteria - Strong factual knowledge with minor weaknesses in understanding - Most but not all ideas/arguments are well presented and few are original

-excellent -Distinction (A- to A) (range 70-100%)Primary criteriaComprehensive knowledge & detailed understanding. Clear evidence of extensive background study & originality. Highly focussed, relevant and well structured answers. Arguments logically presented and defended with evidence and examples. Excellent presentation skills with very accurate communication.Secondary CriteriaA Outstanding - Exceeds expectations for most primary criteria - Complete command of subject and other relevant areas - Ideas/arguments are highly originalA+ Excellent - Exceeds expectations for some primary criteria - Complete command of subject - Ideas/arguments are highly originalA Good - Meets all primary criteria - Command of subject but with minor gaps in knowledge areas - Ideas/arguments are mostly originalA- Meets requirements of Class - Meets most but not all primary criteria - Complete command of subject but with some gaps in knowledge - Ideas/arguments are mostly original

Learning Outcomes

  • Critically interpret functional applications of genomic, transcriptome, metabolome and proteome data in pathogenicity and disease biomarker discovery 

  • Demonstrate subject expertise and understanding of methodologies and technologies employed in whole exome and genome library preparation, and transcriptome, metabolome, proteome assessment and analysis

  • Evaluate the pathogenicity of variants in the context of clinical reporting

Assessment method

Exam (Centrally Scheduled)

Assessment type

Summative

Description

The end of module examination will open over a specific time period during the end of semester 1 examination period, within weeks 20-21. An exam will require the completion of two, from a choice of three, essay type answers each with a maximum word length of 1500 words All questions will have an equal weighting, of 30% of the overall module grade. Essay questions will be delivered in electronic format and a word document template with specific formatting must be utilised to complete and submit answers. All completed documents will be submitted to online databases for determination of originality and similarity. Feedback will be supplied via Turnitin, rubrics and text comments

Weighting

60%

Assessment method

Individual Presentation

Assessment type

Summative

Description

Students will be required to choose an example of a pathogen that is the cause of an infectious disease and outline how genomics can be employed to aid treatment

Weighting

40%

Home

Study

  • Undergraduate Study
Home

Follow Us

  • Twitter
  • Facebook
  • Instagram
  • Youtube
  • LinkedIn

Bangor University

Bangor, Gwynedd, LL57 2DG, UK

+44 (0)1248 351151

Contact Us

Visit Us

Maps & Directions

Policy

  • Legal Compliance
  • Modern Slavery Act 2015 Statement
  • Accessibility Statement
  • Privacy and Cookies
  • Welsh Language Policy
Map

Bangor University is a Registered Charity: No. 1141565

© 2020 Bangor University