Modiwl MSE-3020:
Drug Development

Ffeithiau’r Modiwl

Rhedir gan School of Medical Sciences

20 Credyd neu 10 Credyd ECTS

Semester 1

Trefnydd: Dr Rachel Hallett

Amcanion cyffredinol

Students successfully completing this third year module should have developed a conceptual understanding of the preclinical and clinical development of drugs including antibiotics, plant-derived drugs, anti-viral drugs, kinase inhibitors, novel compounds and antibodies. They should also acquire an understanding of how drugs interact with the body and how information can be retrieved from biopharmaceutical data bases.

The module is organised around 4 topics:

Topic 1: Drug Development & Pharmacokinetics

Topic 2: Antivirals & antibiotics

Topic 3: Kinase inhibitors and plant-derived drugs

Topic 4: Therapeutic antibodies and the immune system as drug

Cynnwys cwrs

Drug Development teaches students about (i) drug-body interactions (pharmacokinetics, pharmacodynamics), (ii) the preclinical and (iii) the clinical development of drugs.

The module uses case studies to explain how drugs are developed from bench to bedside. Examples are selected from a broad range of drugs including antibiotics, plant-derived products, kinase inhibitors and the immune system.

The content of the module is annually updated to incorporate novel developments.

Meini Prawf

da

Category B (60%-69%):

Knowledge of key areas & principles. The main areas are understood with some minor omissions. Limited evidence of background study. Answers are focused on question, but also with some irrelevant material and weaknesses in structure. Arguments presented but lack sometimes coherence. No original interpretation & ideas. Only major links between topics are described. Answers are based on lecture material. Evidence of problem solving & time management skills. Some weaknesses in presentation and accuracy.

trothwy

Category D (40%-49%):

Knowledge is limited to key areas & principles with gaps. No evidence of background reading. Answers are poorly focused with some irrelevant material and/or repetition. No original interpretation and ideas. Limited problem solving skills, poor time management. Many weaknesses in presentation and accuracy.

C- i C+

Category C (50%-59%):

Knowledge is limited to key areas & principles with gaps. No evidence of background reading. Answers are largely correct but are based on statements of facts without additional explanation and context. No original interpretation and ideas. Limited problem solving skills, poor time management. Many weaknesses in presentation and accuracy.

ardderchog

Category A (70%-100%):

Comprehensive knowledge & detailed understanding with clear evidence of background study. Highly focused answer and well structured and well supported by diagrams & tables. Logically presented and defended arguments. No factual errors. Original interpretation and novel links between topics are developed. Excellent problem solving & time management skills. Very good presentation and accuracy.

To obtain marks in the A+ and A* range, clear evidence of background reading has to be present. Top answers based on the lecture material return low A marks.

Canlyniad dysgu

  1. Develop an effective approach to exam revision by preparing for a final exam consisting of 2 essays (exam training is provided).

  2. Communicate effectively to an educated lay audience, using the recent development of a drug as the subject of an article.

  3. Demonstrate an advanced insight into how drugs are developed (pre- & clinical stages).

  4. Demonstrate a detailed understanding of how drugs interact with the body (pharmacokinetics, pharmacodynamics).

Dulliau asesu

Math Enw Disgrifiad Pwysau
ADDRODDIAD New Scientist Drug Report

Students write a report in the style of a New Scientist article, describing the development and pharmacological characteristics of a drug in therapeutic use.

50
ARHOLIAD Essay examination

Two hour written exam. Students answer 2 essay questions from a choice of 4.

50

Strategaeth addysgu a dysgu

Oriau
Private study

Time to research and prepare the Drug Report and to carry out revision and additional directed reading. Engagement with feedback sessions.

178
Lecture

8 x 2 hour lectures 1 x 2 hour student led session - pharmaceutical company meeting simulation.

18
Tutorial

2 x 2 hour tutorials. Review of the key points & concepts. Exam guidance and small group peer feedback on draft drug reports.

4

Sgiliau Trosglwyddadwy

  • Llythrennedd - Medrusrwydd mewn darllen ac ysgrifennu drwy amrywiaeth o gyfryngau
  • Rhifedd - Medrusrwydd wrth ddefnyddio rhifau ar lefelau priodol o gywirdeb
  • Defnyddio cyfrifiaduron - Medrusrwydd wrth ddefnyddio ystod o feddalwedd cyfrifiadurol
  • Hunanreolaeth - Gallu gweithio mewn ffordd effeithlon, prydlon a threfnus. Gallu edrych ar ganlyniadau tasgau a digwyddiadau, a barnu lefelau o ansawdd a phwysigrwydd
  • Archwilio - Gallu ymchwilio ac ystyried dewisiadau eraill
  • Adalw gwybodaeth - Gallu mynd at wahanol ac amrywiol ffynonellau gwybodaeth
  • Sgiliau Rhyngbersonol - Gallu gofyn cwestiynau, gwrando'n astud ar atebion a'u harchwilio
  • Dadansoddi Beirniadol & Datrys Problem - Gallu dadelfennu a dadansoddi problemau neu sefyllfaoedd cymhleth. Gallu canfod atebion i broblemau drwy ddadansoddiadau ac archwilio posibiliadau
  • Cyflwyniad - Gallu cyflwyno gwybodaeth ac esboniadau yn glir i gynulleidfa. Trwy gyfryngau ysgrifenedig neu ar lafar yn glir a hyderus.
  • Gwaith Tîm - Gallu cydweithio'n adeiladol ag eraill ar dasg gyffredin, ac/neu fod yn rhan o dîm gweithio o ddydd i ddydd
  • Dadl - Gallu cyflwyno, trafod a chyfiawnhau barn neu lwybr gweithredu, naill ai gydag unigolyn neu mewn grwˆp ehangach
  • Hunanymwybyddiaeth & Ystyried - Bod yn ymwybodol o'ch cryfderau, gwendidau, nodau ac amcanion eich hun. Gallu adolygu ,cloriannu a myfyrio'n rheolaidd ar eich perfformiad eich hun ac eraill.

Adnoddau

Goblygiadau o ran adnoddau ar gyfer myfyrwyr

None

Rhestrau Darllen Bangor (Talis)

http://readinglists.bangor.ac.uk/modules/mse-3020.html

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